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PEC Original Annotations
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Essentiality
|
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
22
(LD)
,
OCL49,51-3 (LD 22B_CRS)
(D)
,
OCL49,51-4 (LD 22B_P/O)
(D)
,
OCL49-1
(D)
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|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
proX
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
proX
Search strains by all related name:
proX b2679 ECK2673 JW2654 osrA proU
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General information (Go to Linear View: )
|
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Gene Name
|
proX
|
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Alternative name
|
b2679,ECK2673,JW2654,osrA,proU
|
|
Location, Length
|
2,805,154 - 2,806,146
(
+
)
;
60.46
min
;
993
(bp) ,
330
(aa)
|
|
Product
|
glycine betaine transporter subunit
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Operon Name
|
proVWX
|
|
Note
|
high-affinity transport system for glycine betaine and proline; periplasmic-binding component of ABC superfamily; GO_component: GO:0042597 - periplasmic space;GO_function: GO:0015596 - glycine betaine/proline porter activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006561 - proline biosynthetic process; GO_process: GO:0006545 - glycine biosynthetic process; GO_process: GO:0006578 - betaine biosynthetic process; GO_process: GO:0006970 - response to osmotic stress
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Function
|
transport; Osmotic adaptation
|
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Gene Ontology
|
GO:0005215
;
transporter activity ( proX )
GO:0005488
;
binding ( proX )
GO:0005515
;
protein binding ( proX )
GO:0006810
;
transport ( proX )
GO:0006865
;
amino acid transport ( proX )
GO:0042597
;
periplasmic space ( proX )
|
|
PID
|
1789034
|
EC number
(KEGG Pathway)
|
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
proX
(
EG10773
)
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Number of removed
|
21 aa cleaved
|
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
PROX_ECOLI
(
P14177
)
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- Protein name
|
Glycine betaine-binding periplasmic protein precursor.
|
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- Synonyms
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- Gene name
|
Name=proX; Synonyms=proU; OrderedLocusNames=b2679, z3981, ECs3542;
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MMBR References
|
J Bacteriol. 1986;166(1):253-9.
Proline transport and osmotic stress response in Escherichia coli K-12.
Grothe S, Krogsrud RL, McClellan DJ, Milner JL, Wood JM.
(
3514577
)
|
Mol Microbiol. 1989;3(8):1025-38.
Molecular characterization of the proU loci of Salmonella typhimurium and Escherichia coli encoding osmoregulated glycine betaine transport systems.
Stirling DA, Hulton CS, Waddell L, Park SF, Stewart GS, Booth IR, Higgins CF.
(
2691838
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MRHSVLFATA FATLISTQTF AADLPGKGIT VNPVQSTITE ETFQTLLVSR ALEKLGYTVN KPSEVDYNVG
0071 YTSLASGDAT FTAVNWTPLH DNMYEAAGGD KKFYREGVFV NGAAQGYLID KKTADQYKIT NIAQLKDPKI
0141 AKLFDTNGDG KADLTGCNPG WGCEGAINHQ LAAYELTNTV THNQGNYAAM MADTISRYKE GKPVFYYTWT
0211 PYWVSNELKP GKDVVWLQVP FSALPGDKNA DTKLPNGANY GFPVSTMHIV ANKAWAEKNP AAAKLFAIMQ
0281 LPVADINAQN AIMHDGKASE GDIQGHVDGW IKAHQQQFDG WVNEALAAQK
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CACTGGCCCT GTTGGTCTGC TGACCCGCCC
-070 ATTCATTAAG TAACTCTGCA CTTGCCCGGT GACGCCGGGC ATTATCACCC TGCCAAAAAA AGGAATAACA
0001 atgcgacata gcgtactttt tgcgacagcg tttgccacgc ttatctctac acaaactttt gctgccgatc
0071 tgccgggcaa aggcattact gttaatccag ttcagagcac catcactgaa gaaaccttcc agacgctgct
0141 ggtcagtcgt gcgctggaga aattaggtta taccgtcaac aaacccagcg aagtagatta caacgttggc
0211 tacacctcgc ttgcttccgg cgatgcaacc ttcaccgccg tgaactggac gccactgcat gacaacatgt
0281 acgaagctgc cggtggcgat aagaaatttt atcgtgaagg ggtatttgtt aacggcgcgg cacagggtta
0351 cctgatcgat aagaaaaccg ccgaccagta caaaatcacc aacatcgcac aactgaaaga tccgaagatc
0421 gccaaactgt tcgataccaa cggcgacgga aaagcggatt taaccggttg taaccctggc tggggctgcg
0491 aaggtgcgat caaccaccag cttgccgcgt atgaactgac caacaccgtg acgcataatc aggggaacta
0561 cgcagcgatg atggccgaca ccatcagtcg ctacaaagag ggcaaaccgg tgttttatta cacctggacg
0631 ccgtactggg tgagtaacga actgaagccg ggcaaagatg tcgtctggtt gcaggtgccg ttctccgcac
0701 tgccgggcga taaaaacgcc gataccaaac tgccgaatgg tgcgaattat ggcttcccgg tcagcaccat
0771 gcatatcgtt gccaacaaag cctgggccga gaaaaacccg gcagcagcga aactgtttgc cattatgcag
0841 ttgccagtgg cagatattaa cgcccagaac gccattatgc atgacggcaa agcctcagaa ggcgatattc
0911 agggacacgt tgatggttgg atcaaagccc accagcagca gttcgatggc tgggtgaatg aggcgctggc
0981 agcgcagaag taaTTTTTAT TCGGGCGGAT AAGGCGTTTT TGCCGCATCC GCCGTTCTGT GCACAATGCC
1051 TGATGCGACG CTGGCGCGTC TTATCATGCC TACAAACCAC ATC
|
