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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCL82
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
manZ
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Related strains
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Strains Search
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Search strains by gene name:
manZ
Search strains by all related name:
manZ b1819 ECK1817 gptB JW1808 mpt ptsM ptsX
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General information (Go to Linear View: )
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Gene Name
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manZ
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Alternative name
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b1819,ECK1817,gptB,JW1808,mpt,ptsM,ptsX
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Location, Length
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1,901,919 - 1,902,770
(
+
)
;
40.99
min
;
852
(bp) ,
283
(aa)
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Product
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mannose-specific enzyme IID component of PTS
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Operon Name
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manXYZ
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Note
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PTS enzyme IID, mannose-specific; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
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transport; Transport of small molecules: Carbohydrates, organic acids, alcohols
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Gene Ontology
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GO:0005351
;
sugar:hydrogen ion symporter activity ( manZ )
GO:0005886
;
plasma membrane ( manZ )
GO:0006810
;
transport ( manZ )
GO:0008643
;
carbohydrate transport ( manZ )
GO:0009401
;
phosphoenolpyruvate-dependent sugar phosphotransferase system ( manZ )
GO:0016020
;
membrane ( manZ )
GO:0016021
;
integral to membrane ( manZ )
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PID
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345297175
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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PTND_ECOLI
(
P08188
)
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- Protein name
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PTS system, mannose-specific IID component
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- Synonyms
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EIID-Man, Mannose- permease IID component, Phosphotransferase enzyme II, D component, EII-M-Man
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- Gene name
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OrderedLocusNames=b1819, c2226, z2862, ECs2529;
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MMBR References
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Eur J Biochem. 1996;239:810-817
Membrane topology of the mannose transporter of Escherichia coli K12.
Huber, F., and B. Erni.
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Mol Gen Genet. 1985;199(3):427-33.
Gene fusions to the ptsM/pel locus of Escherichia coli.
Palva ET, Saris P, Silhavy TJ.
(
3162078
)
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Proc Natl Acad Sci U S A. 1986;83:8934-8938
Pel, the protein that permits lambda DNA penetration of Escherichia coli, is encoded by a gene in ptsM and is required for mannose utilization by the phosphotransferase system.
Williams, N., D. K. Fox, C. Shea, and S. Roseman.
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J Bacteriol. 1975;122(3):1189-99.
Phosphorylation of D-glucose in Escherichia coli mutants defective in glucosephosphotransferase, mannosephosphotransferase, and glucokinase.
Curtis SJ, Epstein W.
(
1097393
)
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| Sequences |
Amino acid
FASTA format
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0001 MVDTTQTTTE KKLTQSDIRG VFLRSNLFQG SWNFERMQAL GFCFSMVPAI RRLYPENNEA RKQAIRRHLE
0071 FFNTQPFVAA PILGVTLALE EQRANGAEID DGAINGIKVG LMGPLAGVGD PIFWGTVRPV FAALGAGIAM
0141 SGSLLGPLLF FILFNLVRLA TRYYGVAYGY SKGIDIVKDM GGGFLQKLTE GASILGLFVM GALVNKWTHV
0211 NIPLVVSRIT DQTGKEHVTT VQTILDQLMP GLVPLLLTFA CMWLLRKKVN PLWIIVGFFV IGIAGYACGL
0281 LGL
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 CATCCAACTT AGCCCGAAAT ACAACCGCGT
-070 AGCCGGTGCG CCTGCTCAGG CAGCTGGTAA CAACGATCTC GATAACGAAC TGGACTAACA GGTGAGCGAA
0001 atggttgata caactcaaac taccaccgag aaaaaactca ctcaaagtga tattcgtggc gtcttcctgc
0071 gttctaacct cttccagggt tcatggaact tcgaacgtat gcaggcactg ggtttctgct tctctatggt
0141 accggcaatt cgtcgcctct accctgagaa caacgaagct cgtaaacaag ctattcgccg tcacctggag
0211 ttctttaaca cccagccgtt cgtggctgcg ccgattctcg gcgtaaccct ggcgctggaa gaacagcgtg
0281 ctaatggcgc agagatcgac gacggtgcta tcaacggtat caaagtcggt ttgatggggc cactggctgg
0351 tgtaggcgac ccgatcttct ggggaaccgt acgtccggta tttgcagcac tgggtgccgg tatcgcgatg
0421 agcggcagcc tgttaggtcc gctgctgttc ttcatcctgt ttaacctggt gcgtctggca acccgttact
0491 acggcgtagc gtatggttac tccaaaggta tcgatatcgt taaagatatg ggtggtggct tcctgcaaaa
0561 actgacggaa ggggcgtcta tcctcggcct gtttgtcatg ggggcattgg ttaacaagtg gacacatgtc
0631 aacatcccgc tggttgtctc tcgcattact gaccagacgg gcaaagaaca cgttactact gtccagacta
0701 ttctggacca gttaatgcca ggcctggtac cactgctgct gacctttgct tgtatgtggc tactgcgcaa
0771 aaaagttaac ccgctgtgga tcatcgttgg cttcttcgtc atcggtatcg ctggttacgc ttgcggcctg
0841 ctgggactgt aaGACTGTTG TACACTACCG GGGCCTTTTG GCCCCGTTTT TTTATCTGGA GGATTAATGA
0911 CAATCACGGA CCTGGTACTG ATTCTTTTCA TCGCCGCACT CC
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