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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCL85,86-8 (AK4-4 / BK6-4)
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
ihfA
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Related strains
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Strains Search
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Search strains by gene name:
ihfA
Search strains by all related name:
ihfA b1712 ECK1710 hid himA JW1702
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General information (Go to Linear View: )
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Gene Name
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ihfA
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Alternative name
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b1712,ECK1710,hid,himA,JW1702
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Location, Length
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1,793,277 - 1,793,576
(
-
)
;
38.65
min
;
300
(bp) ,
99
(aa)
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Product
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integration host factor (IHF), DNA-binding protein, alpha subunit
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Operon Name
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thrS-infC-rpmI-rplT-pheMST-ihfA
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Note
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integration host factor (IHF), alpha subunit; site specific recombination; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006310 - DNA recombination
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Function
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factor; DNA - replication, repair,restriction/modification
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Gene Ontology
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GO:0003677
;
DNA binding ( ihfA )
GO:0005694
;
chromosome ( ihfA )
GO:0006310
;
DNA recombination ( ihfA )
GO:0006350
;
transcription ( ihfA )
GO:0006355
;
regulation of transcription, DNA-dependent ( ihfA )
GO:0006417
;
regulation of translation ( ihfA )
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PID
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1788005
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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IHFA_ECOLI
(
P06984
)
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- Protein name
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Integration host factor alpha-subunit
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- Synonyms
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IHF-alpha
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- Gene name
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OrderedLocusNames=b1712, c2109, z2741, ECs2419, SF1519, S1636;
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MMBR References
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Nucleic Acids Res. 1995;23:2959-2965
In vivo interaction of the Escherichia coli integration host factor with its specific binding sites
Engelhorn, M., F. Boccard, C. Murtin, P. Prentki, and J. Geiselmann.
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Nucleic Acids Res. 1996;24:1780-1786
Examining the contribution of a dA+dT element to the conformation of Escherichia coli integration host factor-DNA complexes.
Hales, L. M., R. I. Gumport, and J. F. Gardner.
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EMBO J. 1992;11:305-313
The isolation and characterization of mutants of the integration host factor (IHF) of Escherichia coli with altered, expanded DNA-binding specificities.
Lee, E. C., L. M. Hales, R. I. Gumport, and J. F. Gardner.
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J Bacteriol. 1985;163(2):787-91.
Sequence of the Escherichia coli pheST operon and identification of the himA gene.
Mechulam Y, Fayat G, Blanquet S.
(
2991205
)
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J Mol Biol. 1987;197(3):453-70.
Dual level control of the Escherichia coli pheST-himA operon expression. tRNA(Phe)-dependent attenuation and transcriptional operator-repressor control by himA and the SOS network.
Mechulam Y, Blanquet S, Fayat G.
(
3326947
)
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J Bacteriol. 1991;173(5):1670-6.
HU and integration host factor function as auxiliary proteins in cleavage of phage lambda cohesive ends by terminase.
Mendelson I, Gottesman M, Oppenheim AB.
(
1825651
)
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Cold Spring Harbor Symp. Quant. Biol. 1984;49:691-8.
Primary structure of the himA gene of Escherichia coli: homology with DNA-binding protein HU and association with the phenylalanyl-tRNA synthetase operon.
Miller HI.
(
6397321
)
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Cold Spring Harbor Symp. Quant. Biol. 1977;42:349-356.
Isolation of Escherichia coli mutants unable to support lambda integrative recombination.
Miller, H. I., and D. I. Friedman.
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Cell. 1980;20(3):711-9.
An E. coli gene product required for lambda site-specific recombination.
Miller HI, Friedman DI.
(
6251971
)
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Nature. 1981;290(5806):523-6.
Direct role of the himA gene product in phage lambda integration.
Miller HI, Nash HA.
(
6261146
)
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Proc Natl Acad Sci U S A. 1981;78:6754-6758
SOS induction and autoregulation of the himA gene for site-specific recombination in Escherichia coli.
Miller, H. I., M. Kirk, and H. Echols.
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Cold Spring Harbor Symp. Quant. Biol. 1978;43:1121-1126.
Site-specific recombination of bacteriophage lambda : the role of host gene products.
Miller, H. I., Y. Kikuchi, H. A. Nash, R. Weisberg, and D. I. Friedman.
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J Bacteriol. 1995;177:5707-5710
Glucose starvation stimulon of Escherichia coli: role of integration host factor in starvation survival and growth phase-dependent protein synthesis.
Nystrom, T.
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Annu Rev Physiol. 1997;59:633-57.
Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities.
Sukharev SI, Blount P, Martinac B, Kung C.
(
9074781
)
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Mol Gen Genet. 1993;237(1-2):273-86.
Integration host factor (IHF) modulates the expression of the pyrimidine-specific promoter of the carAB operons of Escherichia coli K12 and Salmonella typhimurium LT2.
Charlier D, Roovers M, Gigot D, Huysveld N, Pierard A, Glansdorff N.
(
8455562
)
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J Bacteriol. 1981;146(1):269-74.
Gene organization around the phenylalanyl-transfer ribonucleic acid synthetase locus in Escherichia coli.
Comer MM.
(
7012115
)
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| Sequences |
Amino acid
FASTA format
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0001 MALTKAEMSE YLFDKLGLSK RDAKELVELF FEEIRRALEN GEQVKLSGFG NFDLRDKNQR PGRNPKTGED
0071 IPITARRVVT FRPGQKLKSR VENASPKDE
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 accagccgta cactcgaaga agaggagatt
-070 gccgctaccg tcgccaaatg tgtagaggca ttaaaagagc gattccaggc atcattgagg gattgaacct
0001 atggcgctta caaaagctga aatgtcagaa tatctgtttg ataagcttgg gcttagcaag cgggatgcca
0071 aagaactggt tgaactgttt ttcgaagaga tccgtcgcgc tctggaaaac ggcgaacagg tgaaactctc
0141 tggttttggt aacttcgatc tgcgtgataa gaatcaacgc ccgggacgta acccgaaaac gggcgaggat
0211 attcccatta cagcacggcg cgtggtgacc ttcagacccg ggcagaagtt aaaaagccgg gtcgaaaacg
0281 cttcgcccaa agacgagtaa tctgatctaa ctaaaaaggc cgctctgcgg ccttttttct tttcactgtc
0351 gaagagtcac cgtaaaatca acgccatgac acttcagcag aacggatacc
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