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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCR28
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
caiC
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Related strains
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Strains Search
|
Search strains by gene name:
caiC
Search strains by all related name:
caiC b0037 ECK0038 JW0036 yaaM
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General information (Go to Linear View: )
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Gene Name
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caiC
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Alternative name
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b0037,ECK0038,JW0036,yaaM
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Location, Length
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36,271 - 37,824
(
-
)
;
0.78
min
;
1554
(bp) ,
517
(aa)
|
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Product
|
putative crotonobetaine/carnitine-CoA ligase
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Operon Name
|
caiTABCDE
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Note
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probable crotonobetaine/carnitine-CoA ligase; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009310 - amine catabolic process
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Function
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putative enzyme; Central intermediary metabolism: Pool, multipurpose conversions
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Gene Ontology
|
GO:0003824
;
catalytic activity ( caiC )
GO:0008152
;
metabolic process ( caiC )
GO:0016405
;
CoA-ligase activity ( caiC )
GO:0016874
;
ligase activity ( caiC )
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PID
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221142682
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EC number
(KEGG Pathway)
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6.3.2.-
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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CAIC_ECOLI
(
P31552
)
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- Protein name
|
Probable crotonobetaine/carnitine-CoA ligase
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- Synonyms
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EC 6.3.2.-
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- Gene name
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Name=caiC; OrderedLocusNames=b0037;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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caiC
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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Chain A, Acetyl Coa Synthetase, Acetylated On Lys609
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Probable crotonobetaine/carnitine-CoA ligase
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PSI-BLAST
|
Probable crotonobetaine/carnitine-CoA ligase
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nr
(database updated :
2007.02.20
)
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BLAST
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crotonobetaine/carnitine-CoA ligase [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
AMP_BINDING
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MMBR References
|
Mol Microbiol. 1994;13(5):775-86.
Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.
Eichler K, Bourgis F, Buchet A, Kleber HP, Mandrand-Berthelot MA.
(
7815937
)
|
J Bacteriol. 1998;180:2599-2608
Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.
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| Sequences |
Amino acid
FASTA format
|
0001 MDIIGGQHLR QMWDDLADVY GHKTALICES SGGVVNRYSY LELNQEINRT ANLFYTLGIR KGDKVALHLD
0071 NCPEFIFCWF GLAKIGAIMV PINARLLCEE SAWILQNSQA CLLVTSAQFY PMYQQIQQED ATQLRHICLT
0141 DVALPADDGV SSFTQLKNQQ PATLCYAPPL STDDTAEILF TSGTTSRPKG VVITHYNLRF AGYYSAWQCA
0211 LRDDDVYLTV MPAFHIDCQC TAAMAAFSAG ATFVLVEKYS ARAFWGQVQK YRATVTECIP MMIRTLMVQP
0281 PSANDQQHRL REVMFYLNLS EQEKDAFCER FGVRLLTSYG MTETIVGIIG DRPGDKRRWP SIGRVGFCYE
0351 AEIRDDHNRP LPAGEIGEIC IKGIPGKTIF KEYFLNPQAT AKVLEADGWL HTGDTGYRDE EDFFYFVDRR
0421 CNMIKRGGEN VSCVELENII AAHPKIQDIV VVGIKDSIRD EAIKAFVVLN EGETLSEEEF FRFCEQNMAK
0491 FKVPSYLEIR KDLPRNCSGK IIRKNLK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aaaggtctgg ccaaagttga ggactaaacg
-070 cgtggcgtca gtcggcttgc ctgactagcg cccgcccaat aacaaacgaa caaaaatgga tagaggtgca
0001 atggatatca ttggcggaca acatctacgt caaatgtggg acgatcttgc ggacgtttac ggtcataaaa
0071 cggcgctgat ttgtgaatcc agcggcggag tcgttaaccg gtatagttat cttgagttaa atcaggagat
0141 taaccgcacg gcaaacctgt tttatacgct ggggattcgc aaaggcgaca aggttgcact acatctcgac
0211 aactgcccgg aatttatctt ttgctggttc gggctggcaa aaattggcgc gattatggtg ccgattaacg
0281 cccgcctgtt gtgcgaggaa agcgcgtgga tcctgcaaaa tagccaggcg tgcctgctgg tgaccagtgc
0351 gcaattctat cctatgtatc aacagattca gcaggaagat gccactcaat tgcggcacat ttgcctgaca
0421 gatgtggcac ttcccgctga tgatggcgtg agttcgttta ctcaactgaa aaatcaacaa cctgccacct
0491 tgtgctatgc accgccgcta tcgactgacg atacggcgga aattctcttc acctccggca ccacctcccg
0561 accgaaaggt gtggtgatta cccattacaa cctgcgcttc gctggatatt actccgcctg gcagtgtgca
0631 ctgcgtgacg atgacgtcta cctgacggta atgcctgcgt ttcatatcga ttgccagtgt actgcggcga
0701 tggcggcgtt ttctgccggg gccacctttg tgctggtcga gaaatacagc gcccgcgcct tctggggaca
0771 ggtacagaag taccgcgcca ccgttaccga atgtattccg atgatgatcc gtacgttgat ggtacagccg
0841 ccttcagcga acgatcagca acaccgcctg cgggaagtga tgttttatct caacttgtcg gagcaggaaa
0911 aagatgcgtt ttgtgaacgc ttcggcgttc gcttgctgac gtcttatggg atgacggaaa ccattgtggg
0981 cattatcggc gatcgtcctg gcgataaacg acgctggccg tcgattggtc gggtggggtt ttgctacgaa
1051 gcggagatcc gcgacgatca caatcgcccg ctcccggctg gtgagatcgg tgaaatctgc attaaaggca
1121 tacctgggaa aaccatcttc aaagagtact ttctcaaccc acaagccact gcgaaagtgc tggaagccga
1191 tggctggctg cataccggcg ataccggata ccgcgacgaa gaggactttt tttatttcgt cgatcgccgc
1261 tgcaatatga ttaaacgtgg cggcgagaat gtctcctgcg tggagctgga aaatattatc gccgcgcacc
1331 cgaaaattca ggacatcgtg gttgtgggta ttaaagattc gattcgcgat gaagccatca aagcatttgt
1401 ggtgctgaat gaaggtgaaa cattgagcga agaggaattt ttccgcttct gcgaacaaaa tatggcgaaa
1471 tttaaagtgc cctcttatct ggagatcaga aaagatctgc cacgtaattg ctcggggaaa ataattagaa
1541 agaatctgaa ataaatgaaa cagcagggaa ctaccctgcc agctaataat cacactctaa aacaatatgc
1611 attttttgca gggatgttgt cgtccctgaa aaagcaaaaa tgga
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