PEC Original Annotations
|
Essentiality
|
Class
|
non-essential
|
References (PMID)
|
J Bacteriol. 1983;156(1):19-29.
Complementation of argG and hisA mutations of Escherichia coli by DNA cloned from the archaebacterium Methanococcus voltae.
Wood AG, Redborg AH, Cue DR, Whitman WB, Konisky J.
(
6352676
)
|
|
Deletion
|
OCL29,30-6 (AK4-11 / BK5-11)
(D)
,
OCL29-3
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
argG
|
Related strains
|
Strains Search
|
Search strains by gene name:
argG
Search strains by all related name:
argG Arg6 argE b3172 ECK3161 JW3140 o447
|
General information (Go to Linear View:)
|
Gene Name
|
argG
|
Alternative name
|
Arg6,argE,b3172,ECK3161,JW3140,o447
|
Location, Length
|
3,316,659 - 3,318,002
(
+
)
;
71.48
min
;
1344
(bp) ,
447
(aa)
|
Product
|
argininosuccinate synthetase
|
Operon Name
|
argG
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006526 - arginine biosynthetic process
|
Function
|
enzyme; Amino acid biosynthesis: Arginine
|
Gene Ontology
|
GO:0000166
;
nucleotide binding ( argG )
GO:0004055
;
argininosuccinate synthase activity ( argG )
GO:0005515
;
protein binding ( argG )
GO:0005524
;
ATP binding ( argG )
GO:0005737
;
cytoplasm ( argE )
GO:0005737
;
cytoplasm ( argG )
GO:0006508
;
proteolysis ( argE )
GO:0006526
;
arginine biosynthetic process ( argE )
GO:0006526
;
arginine biosynthetic process ( argG )
GO:0008237
;
metallopeptidase activity ( argE )
GO:0008270
;
zinc ion binding ( argE )
GO:0008652
;
amino acid biosynthetic process ( argE )
GO:0008652
;
amino acid biosynthetic process ( argG )
GO:0008777
;
acetylornithine deacetylase activity ( argE )
GO:0016787
;
hydrolase activity ( argE )
GO:0016874
;
ligase activity ( argG )
GO:0046872
;
metal ion binding ( argE )
GO:0046983
;
protein dimerization activity ( argE )
GO:0050897
;
cobalt ion binding ( argE )
|
PID
|
1789563
|
EC number
(KEGG Pathway)
|
6.3.4.5
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
EcoGene
|
argG
(
EG10068
)
|
Number of removed
|
1 aa cleaved
|
SWISS-PROT
(
Show details
[
4
more]
)
|
Entry name(Acc.no)
|
ASSY_ECOLI
(
P22767
)
|
- Protein name
|
Argininosuccinate synthase
|
- Synonyms
|
EC 6.3.4.5, Citrulline--aspartate ligase
|
- Gene name
|
Name=argG; OrderedLocusNames=b3172, c3929;
|
MMBR References
|
J Bacteriol. 1992;174(11):3836-7.
Physical map location of the argFGH operon of Escherichia coli.
Hendrickson W, Rudd KE.
(
1592837
)
|
Gene. 1990;95(1):99-104.
Sequences of the genes encoding argininosuccinate synthetase in Escherichia coli and Saccharomyces cerevisiae: comparison with methanogenic archaebacteria and mammals.
Van Vliet F, Crabeel M, Boyen A, Tricot C, Stalon V, Falmagne P, Nakamura Y, Baumberg S, Glansdorff N.
(
2123815
)
|
Sequences |
Amino acid
FASTA format
|
0001 MTTILKHLPV GQRIGIAFSG GLDTSAALLW MRQKGAVPYA YTANLGQPDE EDYDAIPRRA MEYGAENARL
0071 IDCRKQLVAE GIAAIQCGAF HNTTGGLTYF NTTPLGRAVT GTMLVAAMKE DGVNIWGDGS TYKGNDIERF
0141 YRYGLLTNAE LQIYKPWLDT DFIDELGGRH EMSEFMIACG FDYKMSVEKA YSTDSNMLGA THEAKDLEYL
0211 NSSVKIVNPI MGVKFWDESV KIPAEEVTVR FEQGHPVALN GKTFSDDVEM MLEANRIGGR HGLGMSDQIE
0281 NRIIEAKSRG IYEAPGMALL HIAYERLLTG IHNEDTIEQY HAHGRQLGRL LYQGRWFDSQ ALMLRDSLQR
0351 WVASQITGEV TLELRRGNDY SILNTVSENL TYKPERLTME KGDSVFSPDD RIGQLTMRNL DITDTREKLF
0421 GYAKTGLLSS SAASGVPQVE NLENKGQ
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ATAAAAGATG ATTAAATGAA AACTCATTTA
-070 TTTTGCATAA AAATTCAGTG AGAGCGGAAA TCCAGGCTCA TCATCAGTTA ATTAAGCAGG GTGTTATTTT
0001 atgacgacga ttctcaagca tctcccggta ggtcaacgta ttggtatcgc tttttctggc ggtctggaca
0071 ccagtgccgc actgctgtgg atgcgacaaa agggagcggt tccttatgca tatactgcaa acctgggcca
0141 gccagacgaa gaggattatg atgcgatccc tcgtcgtgcc atggaatacg gcgcggagaa cgcacgtctg
0211 atcgactgcc gcaaacaact ggtggccgaa ggtattgccg ctattcagtg tggcgcattt cataacacca
0281 ccggcggcct gacctatttc aacacgacgc cgctgggccg cgccgtgact ggtaccatgc tggttgctgc
0351 gatgaaagaa gatggcgtga atatctgggg tgacggtagc acctacaaag gaaacgatat cgaacgtttc
0421 tatcgttatg gtctgctgac caatgctgaa ctgcagattt acaaaccgtg gcttgatact gactttattg
0491 atgaactggg cggccgtcat gagatgtctg aatttatgat tgcctgcggt ttcgactaca aaatgtctgt
0561 cgaaaaagcc tactccacag actccaacat gcttggtgca acgcatgaag cgaaggatct ggaatacctc
0631 aactccagcg tcaaaatcgt caacccgatt atgggcgtga aattctggga tgagagcgtg aagatcccgg
0701 cagaagaagt cacagtacgc tttgaacaag gtcatccggt ggcgctgaac ggtaaaacct ttagcgacga
0771 cgtagaaatg atgctggaag ctaaccgcat cggcggtcgt cacggcctgg gcatgagcga ccagattgaa
0841 aaccgtatca tcgaagcgaa aagccgtggt atttacgaag ctccggggat ggcactgctg cacattgcgt
0911 atgaacgcct gttgaccggt attcacaacg aagacaccat tgagcagtat cacgcgcatg gtcgtcagtt
0981 gggccgtctg ctgtaccagg ggcgttggtt tgactcccag gcgctgatgc tgcgtgactc tctgcaacgc
1051 tgggttgcca gccagatcac tggtgaagtt accctggagc tgcgccgtgg gaacgattat tcaatcctga
1121 ataccgtctc agagaacctg acctacaagc cagagcgtct gacgatggaa aaaggcgact cggtgttctc
1191 gccagatgat cgtattggtc aattgaccat gcgtaacctg gatatcactg atacccgcga gaaacttttc
1261 ggttatgcca aaactggcct gctttcctcc tctgccgctt caggcgtgcc gcaggtggag aatctggaaa
1331 acaaaggcca gtaaTTCGAC ATCAACCCTG CCCTTCAGGG GTGGGGTTAC CTTGCTTATC CTCTGTAAAC
1401 TCCTTTCTGA GCATCACATA ATCGAAAACA TCATGGTTTG CATC
|