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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Mol Gen Genet. 1986;203(3):435-44.
Relationship between pseudo-HPr and the PEP: fructose phosphotransferase system in Salmonella typhimurium and Escherichia coli.
Geerse RH, Ruig CR, Schuitema AR, Postma PW.
(
3528748
)
|
|
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Deletion
|
OCL73-1
(D)
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|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
fruA
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Related strains
|
|
Strains Search
|
Search strains by gene name:
fruA
Search strains by all related name:
fruA b2167 ECK2160 JW2154 ptsF
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General information (Go to Linear View: )
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Gene Name
|
fruA
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Alternative name
|
b2167,ECK2160,JW2154,ptsF
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Location, Length
|
2,257,741 - 2,259,432
(
-
)
;
48.66
min
;
1692
(bp) ,
563
(aa)
|
|
Product
|
fused fructose-specific PTS enzymes:IIBcomponent/IIC components
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Operon Name
|
fruBKA
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Note
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PTS system, fructose-specific transport protein; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process
|
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Function
|
regulator; Degradation of small molecules: Carbon compounds
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Gene Ontology
|
GO:0005351
;
sugar:hydrogen ion symporter activity ( fruA )
GO:0005886
;
plasma membrane ( fruA )
GO:0006810
;
transport ( fruA )
GO:0008643
;
carbohydrate transport ( fruA )
GO:0008982
;
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity ( fruA )
GO:0009401
;
phosphoenolpyruvate-dependent sugar phosphotransferase system ( fruA )
GO:0016020
;
membrane ( fruA )
GO:0016021
;
integral to membrane ( fruA )
GO:0016301
;
kinase activity ( fruA )
GO:0016740
;
transferase activity ( fruA )
|
|
PID
|
1788492
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EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
PTFB_ECOLI
(
P20966
)
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- Protein name
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PTS system, fructose-specific IIBC component
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- Synonyms
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EIIBC-Fru, Fructose- permease IIBC component, Phosphotransferase enzyme II, BC component, EC 2.7.1.69, EII-Fru
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- Gene name
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Name=fruA; Synonyms=ptsF; OrderedLocusNames=b2167;
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Homology Analysis
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BLAST
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Bacteria
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|
GTOP
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fruA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
|
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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PTS system fructose-specific EIIBC component
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PSI-BLAST
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PTS system fructose-specific EIIBC component
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nr
(database updated :
2007.02.20
)
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BLAST
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fused fructose-specific PTS enzymes: IIBcomponent/IIC components [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
LEUCINE_ZIPPER
PTS_EIIA_2
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MMBR References
|
Mol Gen Genet. 1986;203(3):435-44.
Relationship between pseudo-HPr and the PEP: fructose phosphotransferase system in Salmonella typhimurium and Escherichia coli.
Geerse RH, Ruig CR, Schuitema AR, Postma PW.
(
3528748
)
|
J Gen Microbiol. 1988;134(10):2757-68.
Nucleotide sequence of fruA, the gene specifying enzyme IIfru of the phosphoenolpyruvate-dependent sugar phosphotransferase system in Escherichia coli K12.
Prior TI, Kornberg HL.
(
3076173
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKTLLIIDAN LGQARAYMAK TLLGAAARKA KLEIIDNPND AEMAIVLGDS IPNDSALNGK NVWLGDISRA
0071 VAHPELFLSE AKGHAKPYTA PVAATAPVAA SGPKRVVAVT ACPTGVAHTF MAAEAIETEA KKRGWWVKVE
0141 TRGSVGAGNA ITPEEVAAAD LVIVAADIEV DLAKFAGKPM YRTSTGLALK KTAQELDKAV AEATPYEPAG
0211 KAQTATTESK KESAGAYRHL LTGVSYMLPM VVAGGLCIAL SFAFGIEAFK EPGTLAAALM QIGGGSAFAL
0281 MVPVLAGYIA FSIADRPGLT PGLIGGMLAV STGSGFIGGI IAGFLAGYIA KLISTQLKLP QSMEALKPIL
0351 IIPLISSLVV GLAMIYLIGK PVAGILEGLT HWLQTMGTAN AVLLGAILGG MMCTDMGGPV NKAAYAFGVG
0421 LLSTQTYGPM AAIMAAGMVP PLAMGLATMV ARRKFDKAQQ EGGKAALVLG LCFISEGAIP FAARDPMRVL
0491 PCCIVGGALT GAISMAIGAK LMAPHGGLFV LLIPGAITPV LGYLVAIIAG TLVAGLAYAF LKRPEVDAVA
0561 KAA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gtaagtcaaa gcaatgtggg tattaccgat
-070 cgtccgcagt tggccgcaat gatggcgcgc gtcgacttac aaccttttaa ctgacagcag gagaggcata
0001 atgaaaacgc tgctgattat tgacgctaat ctcggtcagg cacgcgccta tatggcgaag accctgctgg
0071 gcgcggcggc gcgaaaagca aaactggaaa tcatcgacaa tccgaacgac gctgaaatgg cgattgttct
0141 cggtgattcc atcccgaacg acagcgcgct gaacggtaaa aatgtctggc tgggcgatat ttcccgggca
0211 gttgcgcacc ctgagctgtt cctgagtgaa gccaaaggcc atgcgaaacc ttacactgcg ccggtcgctg
0281 cgacagcacc agttgccgcc agcggtccga aacgcgtagt tgcggtgact gcttgcccga ctggcgtagc
0351 acacaccttt atggcggctg aagccattga aaccgaagcg aaaaaacgtg gctggtgggt gaaagttgaa
0421 acccgtggtt ctgttggcgc gggtaatgca atcactcccg aagaagtcgc agcagcggat ctggtgattg
0491 tggcggcaga tatcgaagtg gatctggcga aatttgctgg taaaccgatg tatcgtacct ctaccggtct
0561 ggcgctgaag aaaaccgcgc aggaactgga taaagcggtt gctgaagcaa cgccgtatga accggcgggc
0631 aaagctcaaa cggcgaccac tgaaagtaag aaagagagtg caggcgcata ccgtcacttg ctgacgggcg
0701 tttcttacat gctgccgatg gtcgttgcag gtggtctgtg tatcgcgctt tcttttgctt ttggtatcga
0771 agcgtttaaa gagccgggta cgttggctgc ggcgctgatg cagattggtg gtggttcagc ctttgcgctg
0841 atggtgccgg tactggcagg ttatattgcc ttttccattg ccgatcgtcc gggcctcact ccgggtctga
0911 ttggcggtat gctggcggtc agcaccggtt ctggcttcat tggtggtatt attgcgggct tcctggctgg
0981 ttacattgcg aagttaatca gtacgcaatt gaaactgcca cagagtatgg aggcgctgaa accgatcctg
1051 atcattccgc taatttccag tctggtggtc ggtctggcga tgatctacct gatcggtaaa ccagttgctg
1121 gcattctcga agggctgact cactggctgc agaccatggg gactgcgaat gcggttctgc tgggggcgat
1191 cctcggtggc atgatgtgta ctgacatggg cggtccggta aacaaagcag cgtacgcatt cggtgtgggt
1261 ctgctgagta ctcaaaccta tggcccgatg gcggcgatta tggcggcagg tatggtgcca ccgctggcaa
1331 tgggtctggc aacaatggtg gcgcgtcgca aattcgacaa agcgcagcag gaaggtggca aagccgctct
1401 ggtattggga ctgtgcttca tttcggaagg tgcaattccg tttgctgctc gtgatccgat gcgtgtgctg
1471 ccgtgctgta tcgtgggtgg ggcgctgact ggcgcaatct caatggcgat tggtgcgaaa ctgatggcac
1541 cgcacggtgg tctgtttgtt ctgctgatcc ctggcgctat tacgccggta ttgggttacc tggtagcaat
1611 tattgccggt acgctggtgg cgggtttggc ctatgccttc ctgaaacgtc cggaagtgga cgcagtagcg
1681 aaagcagcgt aataaaaggt gtgttacagg gcagaaattt cctgtcctgt aacatttgat gagcgcaaag
1751 agaatgaccg gtttgtgaat gtaattttat gaatttaaat gg
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