PEC Original Annotations
|
Essentiality
|
Class
|
non-essential
|
References (PMID)
|
Proc Natl Acad Sci U S A. 1990;87(1):360-3.
Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12.
Lejeune P, Danchin A.
(
2404280
)
|
|
Deletion
|
15
(LD)
,
DE(pgl-grxA)502
,
15+dps
(LD)
,
OCR48,49-5
(D)
,
OCR48,50-8 (LD 15D::Cm)
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
moaA
|
Related strains
|
Strains Search
|
Search strains by gene name:
moaA
Search strains by all related name:
moaA b0781 bisA chlA ECK0770 JW0764 narA
|
General information (Go to Linear View:)
|
Gene Name
|
moaA
|
Alternative name
|
b0781,bisA,chlA,ECK0770,JW0764,narA
|
Location, Length
|
816,267 - 817,256
(
+
)
;
17.59
min
;
990
(bp) ,
329
(aa)
|
Product
|
molybdopterin biosynthesis protein A
|
Operon Name
|
moaABCDE
|
Note
|
molybdopterin biosynthesis, protein A; GO_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process
|
Function
|
enzyme; Biosynthesis of cofactors, carriers: Molybdopterin
|
Gene Ontology
|
GO:0000166
;
nucleotide binding ( moaA )
GO:0003824
;
catalytic activity ( moaA )
GO:0005506
;
iron ion binding ( moaA )
GO:0005525
;
GTP binding ( moaA )
GO:0006777
;
Mo-molybdopterin cofactor biosynthetic process ( moaA )
GO:0008152
;
metabolic process ( moaA )
GO:0019008
;
molybdopterin synthase complex ( moaA )
GO:0046872
;
metal ion binding ( moaA )
GO:0051536
;
iron-sulfur cluster binding ( moaA )
GO:0051539
;
4 iron, 4 sulfur cluster binding ( moaA )
|
PID
|
1786999
|
EC number
(KEGG Pathway)
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
EcoGene
|
moaA
(
EG11595
)
|
Number of removed
|
0 aa cleaved
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
MOAA_ECOLI
(
P30745
)
|
- Protein name
|
Molybdenum cofactor biosynthesis protein A.
|
- Synonyms
|
|
- Gene name
|
Name=moaA; Synonyms=chlA1, chlA, narA, bisA; OrderedLocusNames=b0781;
|
MMBR References
|
J Bacteriol. 1982;149(2):469-78.
Molybdenum cofactor requirement for biotin sulfoxide reduction in Escherichia coli.
del Campillo-Campbell A, Campbell A.
(
6460021
)
|
J Bacteriol. 1979;138(3):726-30.
Use of chlC-lac fusions to determine regulation of gene chlC in Escherichia coli K-12.
Fimmel AL, Haddock BA.
(
110766
)
|
Mol Gen Genet. 1972;116(1):1-10.
Comparison of nitrate reductase mutants of Escherichia coli selected by alternative procedures.
Glaser JH, DeMoss JA.
(
4558444
)
|
Proc Natl Acad Sci U S A. 1968;61(3):956-62.
A deletion analysis of prophage lambda and adjacent genetic regions.
Adhya S, Cleary P, Campbell A.
(
5246560
)
|
Microbiol. Rev. 1983;47:180-230.
Linkage map of Escherichia coli K-12, edition 7.
Bachmann, B. J.
|
J Bacteriol. 1987;169(1):117-25.
Involvement of chlA, E, M, and N loci in Escherichia coli molybdopterin biosynthesis.
Johnson ME, Rajagopalan KV.
(
2947896
)
|
Mol Microbiol. 1991;5(4):901-7.
Regulation of the chlA locus of Escherichia coli K12: involvement of molybdenum cofactor.
Baker KP, Boxer DH.
(
1906967
)
|
J Gen Microbiol. 1976;93(1):173-6.
A novel method for isolating chlorate-resistant mutants of Escherichia coli K12 by anaerobic selection on a lactate plus fumarate medium.
Lambdren PR, Guest JR.
(
772165
)
|
Mol Gen Genet. 1987;206(2):352-5.
Cloning of seven differently complementing DNA fragments with chl functions from Escherichia coli K12.
Reiss J, Kleinhofs A, Klingmuller W.
(
3035339
)
|
Mol Microbiol. 1992;6(22):3452-4.
Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium.
Shanmugam KT, Stewart V, Gunsalus RP, Boxer DH, Cole JA, Chippaux M, DeMoss JA, Giordano G, Lin EC, Rajagopalan KV.
(
1484496
)
|
Mol Gen Genet. 1968;103(2):127-40.
Transduction of nitrate reductase loci of Escherichia coli by phages P-1 and lambda.
Venables WA, Guest JR.
(
4890160
)
|
J Bacteriol. 1975;121(1):259-66.
Positive selection of mutants with deletions of the gal-chl region of the Salmonella chromosome as a screening procedure for mutagens that cause deletions.
Alper MD, Ames BN.
(
1090571
)
|
Sequences |
Amino acid
FASTA format
|
0001 MASQLTDAFA RKFYYLRLSI TDVCNFRCTY CLPDGYKPSG VTNKGFLTVD EIRRVTRAFA RLGTEKVRLT
0071 GGEPSLRRDF TDIIAAVREN DAIRQIAVTT NGYRLERDVA SWRDAGLTGI NVSVDSLDAR QFHAITGQDK
0141 FNQVMAGIDA AFEAGFEKVK VNTVLMRDVN HHQLDTFLNW IQHRPIQLRF IELMETGEGS ELFRKHHISG
0211 QVLRDELLRR GWIHQLRQRS DGPAQVFCHP DYAGEIGLIM PYEKDFCATC NRLRVSSIGK LHLCLFGEGG
0281 VNLRDLLEDD TQQQALEARI SAALREKKQT HFLHQNNTGI TQNLSYIGG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GGTCAACTGA TACGGTGCTT TGGCCGTGAC
-070 AATGCTCGTA AAGATTGCCA CCAGGGCGAA GGAAGAAATG ACTTCGCCTC CCGTATCTGG AAAGGTGTAC
0001 atggcttcac aactgactga tgcatttgcg cgtaagtttt actacttgcg cctgtcgatt accgatgtgt
0071 gtaactttcg ttgcacctac tgcctgccgg atggctacaa accgagcggc gtcaccaata aaggctttct
0141 taccgtcgat gaaattcgcc gggttacgcg cgccttcgcc agactgggca ccgaaaaagt gcgcctgaca
0211 ggaggagagc cgtctttacg ccgcgacttt accgatatca tcgccgctgt gcgggaaaac gacgctatcc
0281 gccagattgc ggtcacaacc aatggttacc gtctggaacg cgatgtggcg agctggcgcg atgcgggact
0351 tactggcatt aacgtcagtg tcgacagtct ggacgcccgc cagtttcacg ctattaccgg gcaggataaa
0421 ttcaaccagg tcatggcagg gattgatgct gcatttgagg ccggttttga gaaggtcaaa gtcaataccg
0491 tgctgatgcg tgatgttaat catcaccagc tcgacacctt tctgaactgg atccagcatc gccctatcca
0561 gctgcgtttc atcgaactga tggaaacggg cgagggcagc gagctcttcc gtaagcatca catctctggt
0631 caggttctgc gtgacgagct actgcgtcgc ggctggatcc accaattacg tcaacgcagc gacggtcccg
0701 cgcaagtctt ttgccatcca gattacgccg gagagattgg ccttatcatg ccgtatgaaa aagacttctg
0771 cgccacttgc aaccgcctgc gcgtttcctc cattggtaaa ctccatctct gcctgtttgg tgaaggcggc
0841 gttaacctgc gcgatctgct ggaagacgat acccagcaac aggcgctgga agcgcgtatt tcagcggcgc
0911 tgcgggagaa gaaacagacc catttcctgc atcaaaacaa caccggtatt acgcaaaact tatcgtacat
0981 tggcggctaa AACGTCAAAA GGAGAGATCA GATGAGTCAG GTAAGCACTG AATTTATCCC GACCCGTATT
1051 GCTATTCTTA CGGTTTCTAA TCGTCGCGGT GAAGAAGACG
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