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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Cell. 1989;56(4):641-9.
A division inhibitor and a topological specificity factor coded for by the minicell locus determine proper placement of the division septum in E. coli.
de Boer PA, Crossley RE, Rothfield LI.
(
2645057
)
|
|
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Deletion
|
OCR65
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
minD
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Related strains
|
|
Strains Search
|
Search strains by gene name:
minD
Search strains by all related name:
minD b1175 ECK1163 JW1164 minB
|
General information (Go to Linear View: )
|
|
Gene Name
|
minD
|
|
Alternative name
|
b1175,ECK1163,JW1164,minB
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|
Location, Length
|
1,223,772 - 1,224,584
(
-
)
;
26.38
min
;
813
(bp) ,
270
(aa)
|
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Product
|
membrane ATPase of the MinC-MinD-MinE system
|
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Operon Name
|
minCDE
|
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Note
|
cell division inhibitor, a membrane ATPase, activates minC; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
|
|
Function
|
enzyme; Cell division
|
|
Gene Ontology
|
GO:0000166
;
nucleotide binding ( minD )
GO:0000917
;
barrier septum formation ( minD )
GO:0000918
;
selection of site for barrier septum formation ( minD )
GO:0005524
;
ATP binding ( minD )
GO:0005886
;
plasma membrane ( minD )
GO:0007049
;
cell cycle ( minD )
GO:0009236
;
cobalamin biosynthetic process ( minD )
GO:0016020
;
membrane ( minD )
GO:0016887
;
ATPase activity ( minD )
GO:0042242
;
cobyrinic acid a,c-diamide synthase activity ( minD )
GO:0051301
;
cell division ( minD )
|
|
PID
|
1787423
|
EC number
(KEGG Pathway)
|
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
minD
(
EG10597
)
|
|
Number of removed
|
1 aa cleaved
|
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
MIND_ECOLI
(
P18197
)
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|
- Protein name
|
Septum site-determining protein minD
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- Synonyms
|
Cell division inhibitor minD
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- Gene name
|
OrderedLocusNames=b1175, c1622, z1937, ECs1669, SF1162, S1248;
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MMBR References
|
J Bacteriol. 1990;172(10):5852-5.
Minicell-forming mutants of Escherichia coli: suppression of both DicB- and MinD-dependent division inhibition by inactivation of the minC gene product.
Labie C, Bouche F, Bouche JP.
(
2211516
)
|
J Bacteriol. 1990;172(10):5610-6.
Interaction between the min locus and ftsZ.
Bi E, Lutkenhaus J.
(
2211499
)
|
Cell. 1997;91(5):685-94.
The MinE ring: an FtsZ-independent cell structure required for selection of the correct division site in E. coli.
Raskin DM, de Boer PA.
(
9393861
)
|
J Bacteriol. 1994;176:6143-6145
The min locus, which confers topological specificity to cell division, is not involved in its coupling with nucleoid separation.
Dassain, M., and J. P. Bouche.
|
EMBO J. 1991;10:4371-4380
The MinD protein is a membrane ATPase required for the correct placement of the Escherichia coli division site.
de Boer, P. A., R. E. Crossley, A. R. Hand, and L. I. Rothfield.
|
Cell. 1989;56(4):641-9.
A division inhibitor and a topological specificity factor coded for by the minicell locus determine proper placement of the division septum in E. coli.
de Boer PA, Crossley RE, Rothfield LI.
(
2645057
)
|
J Bacteriol. 1988;170(5):2106-12.
Isolation and properties of minB, a complex genetic locus involved in correct placement of the division site in Escherichia coli.
de Boer PA, Crossley RE, Rothfield LI.
(
2834323
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MARIIVVTSG KGGVGKTTSS AAIATGLAQK GKKTVVIDFD IGLRNLDLIM GCERRVVYDF VNVIQGDATL
0071 NQALIKDKRT ENLYILPASQ TRDKDALTRE GVAKVLDDLK AMDFEFIVCD SPAGIETGAL MALYFADEAI
0141 ITTNPEVSSV RDSDRILGIL ASKSRRAENG EEPIKEHLLL TRYNPGRVSR GDMLSMEDVL EILRIKLVGV
0211 IPEDQSVLRA SNQGEPVILD INADAGKAYA DTVERLLGEE RPFRFIEEEK KGFLKRLFGG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tcccagcaga attttatggc aaagcggcgc
-070 gactgcagtt agtcgaaaac gctttgaccg ttcaaccgtt aaattgatcc ctttttaaca aggaatttct
0001 atggcacgca ttattgttgt tacttcgggc aaagggggtg ttggtaagac aacctccagc gcggccatcg
0071 ccactggttt ggcccagaag ggaaagaaaa ctgtcgtgat agattttgat atcggcctgc gtaatctcga
0141 cctgattatg ggttgtgaac gccgggtcgt ttacgatttc gtcaacgtca ttcagggcga tgcaacgcta
0211 aatcaggcgt taattaaaga taagcgtact gaaaatctct atattctgcc ggcatcgcaa acacgcgata
0281 aagatgccct cacccgtgaa ggggtcgcca aagttcttga tgatctgaaa gcgatggatt ttgaatttat
0351 cgtttgtgac tccccggcag ggattgaaac cggtgcgtta atggcactct attttgcaga cgaagccatt
0421 attaccacca acccggaagt ctcctcagta cgcgactctg accgtatttt aggcattctg gcgtcgaaat
0491 cacgccgcgc agaaaatggc gaagagccta ttaaagagca cctgctgtta acgcgctata acccaggccg
0561 cgtaagcaga ggtgacatgc tgagcatgga agatgtgctg gagatcctgc gcatcaaact cgtcggcgtg
0631 atcccagagg atcaatcagt attgcgcgcc tctaaccagg gtgaaccggt cattctcgac attaacgccg
0701 atgcgggtaa agcctacgca gataccgtag aacgtctgtt gggagaagaa cgtcctttcc gcttcattga
0771 agaagagaag aaaggcttcc tcaaacgctt gttcggagga taagttatgg cattactcga tttctttctc
0841 tcgcggaaga aaaacacagc caacattgca aaagaacggc tgcagattat tgttgctgaa cgccgtcgca
0911 gcg
|
