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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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J Bacteriol. 1998;180(23):6429-32.
mraY is an essential gene for cell growth in Escherichia coli.
Boyle DS, Donachie WD.
(
9829961
)
|
|
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Deletion
|
OCR30,31-3 (BK2-1 / AK1-1)
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
mraY
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Related strains
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Strains Search
|
Search strains by gene name:
mraY
Search strains by all related name:
mraY b0087 ECK0088 JW0085 murX
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General information (Go to Linear View: )
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Gene Name
|
mraY
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Alternative name
|
b0087,ECK0088,JW0085,murX
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Location, Length
|
96,002 - 97,084
(
+
)
;
2.07
min
;
1083
(bp) ,
360
(aa)
|
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Product
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phospho-N-acetylmuramoyl-pentapeptide transferase
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Operon Name
|
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC
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Note
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phospho-N-acetylmuramoyl-pentapeptide transferase?; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009252 - peptidoglycan biosynthetic process
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Function
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enzyme; Murein sacculus, peptidoglycan
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Gene Ontology
|
GO:0000287
;
magnesium ion binding ( mraY )
GO:0005886
;
plasma membrane ( mraY )
GO:0007047
;
cell wall organization and biogenesis ( mraY )
GO:0007049
;
cell cycle ( mraY )
GO:0008360
;
regulation of cell shape ( mraY )
GO:0008963
;
phospho-N-acetylmuramoyl-pentapeptide-transferase activity ( mraY )
GO:0009252
;
peptidoglycan biosynthetic process ( mraY )
GO:0016020
;
membrane ( mraY )
GO:0016021
;
integral to membrane ( mraY )
GO:0016740
;
transferase activity ( mraY )
GO:0030145
;
manganese ion binding ( mraY )
GO:0051301
;
cell division ( mraY )
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PID
|
1786275
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EC number
(KEGG Pathway)
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2.7.8.13
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
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MRAY_ECOLI
(
P15876
)
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- Protein name
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Phospho-N-acetylmuramoyl-pentapeptide-transferase
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- Synonyms
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EC 2.7.8.13, UDP- MurNAc-pentapeptide phosphotransferase
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- Gene name
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Name=mraY; Synonyms=murX; OrderedLocusNames=b0087, SF0084, S0086;
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Homology Analysis
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BLAST
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|
Bacteria
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GTOP
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mraY
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Phospho-N-acetylmuramoyl-pentapeptide-transferase (UDP-MurNAc-pentapeptide phosphotransferase)
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|
PSI-BLAST
|
Phospho-N-acetylmuramoyl-pentapeptide-transferase
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
phospho-N-acetylmuramoyl-pentapeptide-transferase [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
MYRISTYL
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MMBR References
|
Nucleic Acids Res. 1990;18(4):1058
Nucleotide sequence involving murD and an open reading frame ORF-Y spacing murF and ftsW in Escherichia coli.
Ikeda M, Wachi M, Ishino F, Matsuhashi M.
(
2179861
)
|
J Bacteriol. 1991;173(3):1021-6.
The Escherichia coli mraY gene encoding UDP-N-acetylmuramoyl-pentapeptide: undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide transferase.
Ikeda M, Wachi M, Jung HK, Ishino F, Matsuhashi M.
(
1846850
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MLVWLAEHLV KYYSGFNVFS YLTFRAIVSL LTALFISLWM GPRMIAHLQK LSFGQVVRND GPESHFSKRG
0071 TPTMGGIMIL TAIVISVLLW AYPSNPYVWC VLVVLVGYGV IGFVDDYRKV VRKDTKGLIA RWKYFWMSVI
0141 ALGVAFALYL AGKDTPATQL VVPFFKDVMP QLGLFYILLA YFVIVGTGNA VNLTDGLDGL AIMPTVFVAG
0211 GFALVAWATG NMNFASYLHI PYLRHAGELV IVCTAIVGAG LGFLWFNTYP AQVFMGDVGS LALGGALGII
0281 AVLLRQEFLL VIMGGVFVVE TLSVILQVGS FKLRGQRIFR MAPIHHHYEL KGWPEPRVIV RFWIISLMLV
0351 LIGLATLKVR
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AATTACTGAT TGCTGAGCAA CAGGTAATTA
-070 CGATTTTAGT TAAGGGTTCA CGTAGTGCCG CCATGGAAGA GGTAGTACGC GCTTTACAGG AGAATGGGAC
0001 atgttagttt ggctggccga acatttggtc aaatattatt ccggctttaa cgtcttttcc tatctgacgt
0071 ttcgcgccat cgtcagcctg ctgaccgcgc tgttcatctc attgtggatg ggcccgcgta tgattgctca
0141 tttgcaaaaa ctttcctttg gtcaggtggt gcgtaacgac ggtcctgaat cacacttcag caagcgcggt
0211 acgccgacca tgggcgggat tatgatcctg acggcgattg tgatctccgt actgctgtgg gcttacccgt
0281 ccaatccgta cgtctggtgc gtgttggtgg tgctggtagg ttacggtgtt attggctttg ttgatgatta
0351 tcgcaaagtg gtgcgtaaag acaccaaagg gttgatcgct cgttggaagt atttctggat gtcggtcatt
0421 gcgctgggtg tcgccttcgc cctgtacctt gccggcaaag acacgcccgc aacgcagctg gtggtcccat
0491 tctttaaaga tgtgatgccg cagctggggc tgttctacat tctgctggct tacttcgtca ttgtgggtac
0561 tggcaacgcg gtaaacctga ccgatggtct cgacggcctg gcaattatgc cgaccgtatt tgtcgccggt
0631 ggttttgcgc tggtggcgtg ggcgaccggc aatatgaact ttgccagcta cttgcatata ccgtatctgc
0701 gacacgccgg ggaactggtt attgtctgta ccgcgatagt cggggcagga ctgggcttcc tgtggtttaa
0771 cacctatccg gcgcaggtct ttatgggcga tgtaggttcg ctggcgttag gtggtgcgtt aggcattatc
0841 gccgtactgc tacgtcagga attcctgctg gtgattatgg ggggcgtgtt cgtggtagaa acgctttctg
0911 tcatcctgca ggtcggctcc tttaaactgc gcggacaacg tattttccgc atggcaccga ttcatcacca
0981 ctatgaactg aaaggctggc cggaaccgcg cgtcattgtg cgtttctgga ttatttcgct gatgctggtt
1051 ctgattggtc tggcaacgct gaaggtacgt taaTCATGGC TGATTATCAG GGTAAAAATG TCGTCATTAT
1121 CGGCCTGGGC CTCACCGGGC TTTCCTGCGT GGACTTTTTC CTCGCTCGCG GTGTGACGCC GCG
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