|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Int J Pept Protein Res. 1979;13(2):146-51.
Soluble di- and aminopeptidases in Escherichia K-12. Dispensible enzymes.
Hermsdorf CL, Simmonds S, Saunders A.
(
372108
)
|
|
|
Deletion
|
OCR05
(D)
,
OCR05-12-1
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
pepQ
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
pepQ
Search strains by all related name:
pepQ b3847 ECK3839 JW3823 o443
|
General information (Go to Linear View: )
|
|
Gene Name
|
pepQ
|
|
Alternative name
|
b3847,ECK3839,JW3823,o443
|
|
Location, Length
|
4,029,184 - 4,030,515
(
+
)
;
86.84
min
;
1332
(bp) ,
443
(aa)
|
|
Product
|
proline dipeptidase
|
|
Operon Name
|
pepQ-yigZ-trkH-hemG
|
|
Note
|
|
|
Function
|
enzyme; Degradation of proteins, peptides, glyco
|
|
Gene Ontology
|
GO:0004251
;
X-Pro dipeptidase activity ( pepQ )
GO:0005515
;
protein binding ( pepQ )
GO:0005737
;
cytoplasm ( pepQ )
GO:0006508
;
proteolysis ( pepQ )
GO:0008233
;
peptidase activity ( pepQ )
GO:0008235
;
metalloexopeptidase activity ( pepQ )
GO:0008237
;
metallopeptidase activity ( pepQ )
GO:0016787
;
hydrolase activity ( pepQ )
GO:0016805
;
dipeptidase activity ( pepQ )
GO:0030145
;
manganese ion binding ( pepQ )
GO:0046872
;
metal ion binding ( pepQ )
|
|
PID
|
1790282
|
EC number
(KEGG Pathway)
|
3.4.13.9
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
PEPQ_ECOLI
(
P21165
;
P21176
)
|
|
- Protein name
|
Xaa-Pro dipeptidase
|
|
- Synonyms
|
EC 3.4.13.9, X-Pro dipeptidase, Proline dipeptidase, Prolidase, Imidodipeptidase
|
|
- Gene name
|
Name=pepQ; OrderedLocusNames=b3847;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
pepQ
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Human Prolidase
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Xaa-Pro dipeptidase
|
|
PSI-BLAST
|
Xaa-Pro dipeptidase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
proline dipeptidase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
PROLINE_PEPTIDASE
|
|
MMBR References
|
Nucleic Acids Res. 1990;18(21):6439
Nucleotide sequence between the fadB gene and the rrnA operon from Escherichia coli.
Nakahigashi K, Inokuchi H.
(
2243799
)
|
Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MESLASLYKN HIATLQERTR DALARFKLDA LLIHSGELFN VFLDDHPYPF KVNPQFKAWV PVTQVPNCWL
0071 LVDGVNKPKL WFYLPVDYWH NVEPLPTSFW TEDVEVIALP KADGIGSLLP AARGNIGYIG PVPERALQLG
0141 IEASNINPKG VIDYLHYYRS FKTEYELACM REAQKMAVNG HRAAEEAFRS GMSEFDINIA YLTATGHRDT
0211 DVPYSNIVAL NEHAAVLHYT KLDHQAPEEM RSFLLDAGAE YNGYAADLTR TWSAKSDNDY AQLVKDVNDE
0281 QLALIATMKA GVSYVDYHIQ FHQRIAKLLR KHQIITDMSE EAMVENDLTG PFMPHGIGHP LGLQVHDVAG
0351 FMQDDSGTHL AAPAKYPYLR CTRILQPGMV LTIEPGIYFI ESLLAPWREG QFSKHFNWQK IEALKPFGGI
0421 RIEDNVVIHE NNVENMTRDL KLA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AAGAAATGCC GATCTGATCA CGCTCGGCAG
-070 AAATCACGCT CTGGATGAAC GATGTGCTAA GATGCGGAGA CTTAAGGTCA AAAAAACAGA AGGGTAAAAA
0001 atggaatcac tggcctcgct ctataaaaat catatagcta ccttacaaga acggactcgc gatgcgctgg
0071 cgcgcttcaa gctggatgcg ttacttattc actccggcga gctgttcaat gtttttctcg acgatcatcc
0141 ctatccgttt aaagtgaacc cgcaattcaa agcgtgggtg ccggtaactc aggtgccaaa ctgctggttg
0211 ctggtggatg gcgtgaacaa gccgaaactg tggttctatc tgccggttga ttactggcac aacgtcgaac
0281 cgctgccgac ctctttctgg actgaagatg tggaagtgat cgcgctgccg aaagccgatg gcattggtag
0351 cctgctgcct gctgcgcgcg gcaatatcgg ttatatcggt ccggtgccgg aacgtgcgct gcaactgggt
0421 attgaggcca gcaacatcaa cccgaaaggg gttatcgact acctgcatta ctatcgctcc ttcaaaactg
0491 agtacgaact ggcctgtatg cgtgaagcgc agaaaatggc ggtcaacggt caccgcgcgg cagaagaagc
0561 gttccgttct ggcatgagcg agttcgatat caacattgcc tatctgaccg cgaccggtca tcgtgatacc
0631 gacgtacctt acagcaacat tgtggcgctt aacgaacacg ctgcggtact gcattacacc aaactggacc
0701 atcaggcacc ggaagagatg cgcagcttcc tgctggatgc cggggcagaa tataacggct atgcggctga
0771 cctgacccgt acctggtcgg caaaaagtga caacgactac gcgcagctgg tgaaggacgt taatgatgaa
0841 caactggcgc tgatcgccac catgaaagca ggcgtcagct atgtggatta ccacatccag ttccatcagc
0911 gcatcgccaa actgctgcgt aaacatcaaa tcatcaccga tatgagtgaa gaagcgatgg tcgaaaacga
0981 tcttaccggg ccgtttatgc cgcatggtat cggccatccg ctgggcctgc aggtgcatga cgtcgctggt
1051 tttatgcagg atgatagcgg tacgcacctc gcggcaccgg caaaatatcc gtacctgcgc tgcacccgta
1121 ttctccagcc gggcatggtg ttaaccatcg aaccgggtat ctacttcatc gaatcgctac tggcaccgtg
1191 gcgtgaaggg cagttcagca agcacttcaa ctggcagaaa attgaagcac tgaaaccgtt cggcggcatt
1261 cgtatcgaag acaacgtggt gatccacgaa aacaacgtgg aaaacatgac ccgggatctg aaactggcgt
1331 gaTGGAAAGC TGGTTAATTC CTGCGGCACC GGTCACGGTC GTTGAAGAGA TCAAAAAGAG CCGCTTCATA
1401 ACGATGTTGG CGCATACCGA TGGCGTTGAG GC
|
