MG1655
W3110
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Gene Report : potH
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion 15 (LD)  ,  15+dps (LD)  ,  OCR48,50-8 (LD 15D::Cm) (D)  ,  OCR49 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  potH
Related strains
     Strains Search Search strains by gene name:  potH   Search strains by all related name:  potH b0856 ECK0847 JW0840

General information  (Go to Linear View:)
 Gene Name potH  
 Alternative name b0856,ECK0847,JW0840  
 Location, Length 895,357 - 896,310 (  +  ) ;   19.30 min ; 954 (bp) ,   317 (aa) Go to Linear View
 Product putrescine transporter subunit: membrane component of ABC superfamily  
 Operon Name potFGHI  
 Note putrescine transport protein; permease; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006596 - polyamine biosynthetic process; GO_process: GO:0009310 - amine catabolic process; GO_process: GO:0015847 - putrescine transport  
 Function transport; Transport of small molecules: Amino acids, amines  
 Gene Ontology GO:0005215 ; transporter activity ( potH )
GO:0005886 ; plasma membrane ( potH )
GO:0006810 ; transport ( potH )
GO:0016020 ; membrane ( potH )
GO:0016021 ; integral to membrane ( potH )
 PID 1787080  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) POTH_ECOLI ( P31135 )
    -  Protein name Putrescine transport system permease protein potH.  
    -  Synonyms  
    -  Gene name Name=potH; OrderedLocusNames=b0856;  
    -  Comments
  • FUNCTION:Required for the activity of the bacterial periplasmic transport system of putrescine.
  • SUBCELLULAR LOCATION:Integral membrane protein. Inner membrane (Potential).
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.  
    •   botton Entry name(Acc.no) Q8FJE8 ( Q8FJE8 )
        -  Protein name Putrescine transport system permease protein potH.  
        -  Synonyms  
        -  Gene name Name=potH; OrderedLocusNames=c0989;  
        -  Comments
  • FUNCTION:Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity).
  • SUBCELLULAR LOCATION:Integral membrane protein (By similarity).
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family.  
    •   botton Entry name(Acc.no) Q8X6Q9 ( Q8X6Q9 )
        -  Protein name Putrescine transport protein; permease.  
        -  Synonyms  
        -  Gene name Name=potH; OrderedLocusNames=z1083;  
        -  Comments
  • FUNCTION:Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity).
  • SUBCELLULAR LOCATION:Integral membrane protein (By similarity).
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family.  

    •  Linear View (Whole Mode)
    View Location
       885.0  –  910.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP potH (  homologous genes of other bacterias  )  
        PDB     (database updated : 2007.02.20 )
            PSI-BLAST  
        SWISS-PROT     (database updated : 2007.02.20 )
             BLAST Putrescine transport system permease protein potH  
             PSI-BLAST Putrescine transport system permease protein potH
        nr     (database updated : 2007.02.20 )
             BLAST putrescine transporter subunit: membrane component of ABC superfamily [Escherichia coli K12]  
    Pfam 28.0   (database updated : 2015-05 )
        Pfam
    PROSITE
        PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION    LEUCINE_ZIPPER    CARBOXYPEPT_ZN_2    BPD_TRANSP_INN_MEMBR     

    Other Cross-Reference
        COG COG1176E 
        EcoCyc potH 

    MMBR References
    J Biol Chem. 1993;268:146-152
    Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome.
    Pistocchi, R., K. Kashiwagi, S. Miyamoto, E. Nukui, H. Kobayashi, and K. Igarashi.

    Sequences
    Amino acid
    FASTA format 
    0001 MSTLEPAAQS KPPGGFKLWL SQLQMKHGRK LVIALPYIWL ILLFLLPFLI VFKISLAEMA RAIPPYTELM 
0071 EWADGQLSIT LNLGNFLQLT DDPLYFDAYL QSLQVAAIST FCCLLIGYPL AWAVAHSKPS TRNILLLLVI 
0141 LPSWTSFLIR VYAWMGILKN NGVLNNFLLW LGVIDQPLTI LHTNLAVYIG IVYAYVPFMV LPIYTALIRI 
0211 DYSLVEAALD LGARPLKTFF TVIVPLTKGG IIAGSMLVFI PAVGEFVIPE LLGGPDSIMI GRVLWQEFFN 
0281 NRDWPVASAV AIIMLLLLIV PIMWFHKHQQ KSVGEHG
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp 
    -100                                             CGCCCATCGT CATCGTAAAG GGTTACCGAC 
-070 CTGGGGCGAC GAAGTGCGTT TGTGCTGGGA AGTGGACAGC TGTGTGGTGC TGACGGTTTA AGGAGCAAAG 
0001 atgagtacac ttgaacctgc tgcccagtcg aaaccgccgg gcggatttaa gctgtggttg tcgcagctgc 
0071 aaatgaagca tgggcgcaaa ctggtcattg cgttgccata tatctggttg atcttgctgt ttctgctgcc 
0141 atttctgatt gtctttaaaa taagcctggc ggagatggcg cgcgctattc caccttatac cgaactgatg 
0211 gagtgggctg acgggcaact gtccatcact cttaatctcg gtaattttct gcaactgacc gacgatccgc 
0281 tctatttcga tgcttatctc cagtcgctac aggtggctgc gatttcgaca ttttgctgtt tactgatcgg 
0351 ctatccgctg gcgtgggcgg tggcgcacag taagccttcg acccgtaata ttttattact actggtgatc 
0421 ctgccgtcgt ggacctcgtt tctgatccgc gtttatgcct ggatgggaat attaaaaaac aacggtgtgc 
0491 tgaataattt tctgctgtgg ctgggggtta tcgatcaacc gctgaccatt ctgcatacca atctggccgt 
0561 ttatatcggc attgtttacg cttacgtgcc gtttatggta ctgccgattt ataccgcgtt gattcgtatt 
0631 gattattcgc tggtggaagc agcgctggat ctcggtgcac gaccgctgaa aacgttcttt actgtgatcg 
0701 tgccgctgac taaaggtggg attattgccg gatcgatgct ggtgtttatc ccggctgtgg gcgagtttgt 
0771 gatcccggaa ctgctcggtg gcccggacag catcatgatc gggcgcgtgc tatggcaaga gtttttcaat 
0841 aaccgcgact ggccggtggc ctcggcggta gcgatcatca tgttgctgct gctaattgtg ccgataatgt 
0911 ggttccacaa acaccagcaa aaaagcgtgg gagaacacgg atgaATAATT TACCGGTAGT TCGTTCGCCC 
0981 TGGCGGATTG TGATTTTGCT GCTGGGCTTT ACCTTTCTCT ACGCGCCAAT GCTGATGCTG GTTATCTATT 
1051 CGTT