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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
J Bacteriol. 1987;169(8):3638-46.
Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli.
Ozenberger BA, Nahlik MS, McIntosh MA.
(
2956250
)
|
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Deletion
|
OCR44,45-2 (LD 12-1_P/O)
(D)
,
OCR45
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
fepD
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Related strains
|
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Strains Search
|
Search strains by gene name:
fepD
Search strains by all related name:
fepD b0590 ECK0583 JW0582
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General information (Go to Linear View: )
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Gene Name
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fepD
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Alternative name
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b0590,ECK0583,JW0582
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Location, Length
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620,408 - 621,412
(
-
)
;
13.37
min
;
1005
(bp) ,
334
(aa)
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Product
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iron-enterobactin transporter subunit
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Operon Name
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fepDGC
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Note
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ferric enterobactin (enterochelin) transport; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006826 - iron ion transport
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Function
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transport; Transport of small molecules: Cations
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Gene Ontology
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GO:0005215
;
transporter activity ( fepD )
GO:0005506
;
iron ion binding ( fepD )
GO:0005886
;
plasma membrane ( fepD )
GO:0006810
;
transport ( fepD )
GO:0006811
;
ion transport ( fepD )
GO:0006826
;
iron ion transport ( fepD )
GO:0016020
;
membrane ( fepD )
GO:0016021
;
integral to membrane ( fepD )
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PID
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1786805
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
|
FEPD_ECOLI
(
P23876
;
P77097
)
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- Protein name
|
Ferric enterobactin transport system permease protein fepD.
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- Synonyms
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- Gene name
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Name=fepD; OrderedLocusNames=b0590;
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- Comments
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FUNCTION:Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane.
SUBCELLULAR LOCATION:Integral membrane protein. Inner membrane.
INDUCTION:Controlled in part by the amount of available iron.
SIMILARITY:Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
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Entry name(Acc.no)
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Q8FK21
(
Q8FK21
)
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- Protein name
|
Ferric enterobactin transport system permease protein fepD.
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- Synonyms
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|
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- Gene name
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Name=fepD; OrderedLocusNames=c0677;
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- Comments
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SIMILARITY:Belongs to the ATP-dependent AMP-binding enzyme family.
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Entry name(Acc.no)
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Q8XBV5
(
Q8XBV5
)
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- Protein name
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Ferric enterobactin (Enterochelin) transport.
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- Synonyms
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- Gene name
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Name=fepD; OrderedLocusNames=z0732;
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- Comments
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SIMILARITY:Contains 1 HTH lysR-type DNA-binding domain.
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MMBR References
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J Bacteriol. 1994;176:3944-3955
Promoter and operator determinants for Fur-mediated iron regulation in the bidirectional fepA-fes control region of the Escherichia coli enterobactin gene system.
Hunt, M. D., G. S. Pettis, and M. A. McIntosh.
|
J Bacteriol. 1987;169(8):3638-46.
Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli.
Ozenberger BA, Nahlik MS, McIntosh MA.
(
2956250
)
|
Mol Microbiol. 1991;5(6):1415-28.
Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
Shea CM, McIntosh MA.
(
1838574
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MSGSVAVTRA IAVPGLLLLL IIATALSLLI GAKSLPASVV LEAFSGTCQS ADCTIVLDAR LPRTLAGLLA
0071 GGALGLAGAL MQTLTRNPLA DPGLLGVNAG ASFAIVLGAA LFGYSSAQEQ LAMAFAGALV ASLIVAFTGS
0141 QGGGQLSPVR LTLAGVALAA VLEGLTSGIA LLNPDVYDQL RFWQAGSLDI RNLHTLKVVL IPVLIAGATA
0211 LLLSRALNSL SLGSDTATAL GSRVARTQLI GLLAITVLCG SATAIVGPIA FIGLMMPHMA RWLVGADHRW
0281 SLPVTLLATP ALLLFADIIG RVIVPGELRV SVVSAFIGAP VLIFLVRRKT RGGA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tgccatcaaa tattttaaat acctattctt
-070 aggctgcaca tgctaacata tccaaataag atcgataacg ataattaatt tcattatcat ggaagttcgt
0001 atgtctggtt ctgttgccgt gacacgcgcc attgccgtgc ccggattgct gttattactg attatcgcga
0071 cggcattaag cctgctcatt ggggcaaaat cactccccgc ttccgtagtg ctggaggcct tctccggcac
0141 ctgccagagc gccgactgca ccatcgtgct cgacgcgcgg ctgccgcgta cccttgccgg tttactggca
0211 ggcggcgcgc ttggccttgc cggggcgtta atgcaaaccc tcacccgaaa cccacttgcc gaccccggct
0281 tgcttggcgt gaacgccgga gccagctttg ccattgtgct gggtgcggcg ctgtttggtt actcttccgc
0351 gcaggaacaa ctggcgatgg ccttcgccgg ggcgctggtg gcctcattga ttgttgcctt taccggcagt
0421 cagggcggcg ggcagttaag tccggtgcgt ttaaccctgg cgggcgtggc gctggcggcg gtgctggaag
0491 gactgaccag cggcatcgcc ctgcttaatc ctgacgtcta cgatcagttg cgtttctggc aagccggttc
0561 gctggatatt cgcaatctac ataccttaaa agtggtgctg atcccggtgc tgatcgccgg agcaactgcg
0631 ctattactga gtcgcgcgct gaacagtttg agcctcggca gcgacaccgc gacggcgctg ggcagtcgcg
0701 tggcgcgcac acagttgatt ggtctgctgg cgattaccgt gctttgtggt agtgcgacgg caatagttgg
0771 cccgattgcc tttattggcc tgatgatgcc gcatatggcg cgttggctgg tgggtgccga tcatcgctgg
0841 tcgctgcccg tcacgctact tgctacccct gccctgctgc tgtttgccga tatcatcggg cgggtgattg
0911 tgcccggcga actgcgcgtt tctgtggtca gtgcgtttat tggtgcaccg gtgctgatct tcctcgtgcg
0981 acgtaaaacg cgaggtggtg catgatttac gtctctcgcc gattactcat cacctgtttg ctgctggttt
1051 ccgcctgtgt ggttgcaggt atctggggat tacgcagcgg tgccgtcacg ctgga
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