MG1655
W3110
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Gene Report : fixX
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Basic Microbiol. 1995;35(4):217-27.
The fix Escherichia coli region contains four genes related to carnitine metabolism.
Eichler K, Buchet A, Bourgis F, Kleber HP, Mandrand-Berthelot MA. ( 7473063 )
     Deletion OCR28 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fixX
Related strains
     Strains Search Search strains by gene name:  fixX   Search strains by all related name:  fixX b0044 ECK0045 JW0043 yaaT

General information  (Go to Linear View:)
 Gene Name fixX  
 Alternative name b0044,ECK0045,JW0043,yaaT  
 Location, Length 45,463 - 45,750 (  +  ) ;   0.98 min ; 288 (bp) ,   95 (aa) Go to Linear View
 Product putative 4Fe-4S ferredoxin-type protein  
 Operon Name fixABCX  
 Note putative ferredoxin; GO_process: GO:0042413 - carnitine catabolic process  
 Function putative carrier; Not classified  
 Gene Ontology GO:0005506 ; iron ion binding ( fixX )
GO:0006118 ; electron transport ( fixX )
GO:0006810 ; transport ( fixX )
GO:0046872 ; metal ion binding ( fixX )
GO:0051536 ; iron-sulfur cluster binding ( fixX )
GO:0051539 ; 4 iron, 4 sulfur cluster binding ( fixX )
 PID 1786228  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) FIXX_ECOLI ( P31576 ; P75627 )
    -  Protein name Ferredoxin-like protein.  
    -  Synonyms  
    -  Gene name Name=fixX; OrderedLocusNames=b0044, c0054, z0050, ECs0047;  
    -  Comments
  • FUNCTION:Could be a 3Fe-4S cluster-containing protein. Probably participates in a redox process with fixA, fixB and fixC.
  • SIMILARITY:Belongs to the bacterial-type ferredoxin family. FixX subfamily.  

  •  Linear View (Whole Mode)
    View Location
       35.0  –  60.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP fixX (  homologous genes of other bacterias  )  
        PDB     (database updated : 2007.02.20 )
             PSI-BLAST Chain B, Formate Dehydrogenase N From E. Coli  
        SWISS-PROT     (database updated : 2007.02.20 )
             BLAST Ferredoxin-like protein fixX  
             PSI-BLAST Ferredoxin-like protein
        nr     (database updated : 2007.02.20 )
             BLAST putative ferredoxin [Escherichia coli O157:H7 EDL933]  
    Pfam 28.0   (database updated : 2015-05 )
        Pfam
    PROSITE
        PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL     

    Other Cross-Reference
        COG COG2440C 
        EcoCyc fixX 

    MMBR References
    J Basic Microbiol. 1995;35(4):217-27.
    The fix Escherichia coli region contains four genes related to carnitine metabolism.
    Eichler K, Buchet A, Bourgis F, Kleber HP, Mandrand-Berthelot MA. ( 7473063 )
    J Bacteriol. 1998;180:2599-2608
    Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
    Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.

    Sequences
    Amino acid
    FASTA format
    0001 MTSPVNVDVK LGVNKFNVDE EHPHIVVKAD ADKQALELLV KACPAGLYKK QDDGSVRFDY AGCLECGTCR 
    0071 ILGLGSALEQ WEYPRGTFGV EFRYG
    
    
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp
    -100                                             GCAGCGCGCC GGAACTGATG CGCAAGAAAA 
    -070 TCCTCCGCCA CGGCAAGAAA GTGGGCTTCA TCAATCTAAT CAAGGATGGC ATGAAAGGAG TGACCGTTTT 
    0001 atgacttctc ccgtcaatgt ggacgtcaaa ctgggcgtca ataaattcaa tgtcgatgaa gagcatccgc 
    0071 acattgttgt gaaggccgat gctgataaac aggcgctgga gctgctggtg aaagcgtgcc ccgcaggtct 
    0141 gtacaagaag caggatgacg gcagtgtgcg cttcgattac gccggatgtc tggagtgcgg cacctgtcgc 
    0211 attctggggc tggggtcggc gctggaacag tgggaatacc cgcgcggcac ctttggtgtg gagttccgtt 
    0281 acggctgaTG TTGGTTTGAT ACGTAACGCC GCACTGACTC TCATTGCAAA AAACAGGAAT AACCATGCAA 
    0351 CCGTCCAGAA ACTTTGACGA TCTCAAATTC TCCTCTAT