MG1655
W3110
Search for
Japanese | English
Top Genes Deletions Circular Linear Motif Contigs Reference SequenceCutter Download Strains TEC
Gene Report : fecE
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Bacteriol. 1989;171(5):2626-33.
Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli.
Staudenmaier H, Van Hove B, Yaraghi Z, Braun V. ( 2651410 )
     Deletion 1 (LD)  ,  OCR20,24-1 (LD 1-1_CRS) (D)  ,  OCR20,24-2 (LD 1-1_P/O) (D)  ,  OCR21 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fecE
Related strains
     Strains Search Search strains by gene name:  fecE   Search strains by all related name:  fecE b4287 ECK4277 f255 JW4247

General information  (Go to Linear View:)
 Gene Name fecE  
 Alternative name b4287,ECK4277,f255,JW4247  
 Location, Length 4,508,713 - 4,509,480 (  -  ) ;   97.18 min ; 768 (bp) ,   255 (aa) Go to Linear View
 Product KpLE2 phage-like element; iron-dicitrate transporter subunit  
 Operon Name fecABCDE  
 Note ATP-binding component of citrate-dependent iron(III) transport protein; ATP-binding component of ABC superfamily; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006826 - iron ion transport  
 Function transport; Transport of small molecules: Cations  
 Gene Ontology GO:0000166 ; nucleotide binding ( fecE )
GO:0005506 ; iron ion binding ( fecE )
GO:0005515 ; protein binding ( fecE )
GO:0005524 ; ATP binding ( fecE )
GO:0005886 ; plasma membrane ( fecE )
GO:0006810 ; transport ( fecE )
GO:0006811 ; ion transport ( fecE )
GO:0006826 ; iron ion transport ( fecE )
GO:0016020 ; membrane ( fecE )
GO:0016887 ; ATPase activity ( fecE )
GO:0017111 ; nucleoside-triphosphatase activity ( fecE )
 PID 1790739  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) FECE_ECOLI ( P15031 )
    -  Protein name Iron(III) dicitrate transport ATP-binding protein fecE.  
    -  Synonyms  
    -  Gene name Name=fecE; OrderedLocusNames=b4287;  
    -  Comments
  • FUNCTION:Part of the binding-protein-dependent transport system for citrate-dependent iron(III). Probably responsible for energy coupling to the transport system.
  • SUBCELLULAR LOCATION:Inner membrane-associated.
  • SIMILARITY:Belongs to the ABC transporter family.  

    •  Linear View (Whole Mode)
    View Location
       4500.0  –  4525.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP fecE (  homologous genes of other bacterias  )  
        PDB     (database updated : 2007.02.20 )
             PSI-BLAST Chain A, Structure Of The Atpase Subunit Cysa Of The Putative Sulfate Atp-Binding Cassette (Abc) Transporter From Alicyclobacillus Acidocaldarius  
        SWISS-PROT     (database updated : 2007.02.20 )
             BLAST Iron  
             PSI-BLAST Phosphate import ATP-binding protein pstB
        nr     (database updated : 2007.02.20 )
             BLAST KpLE2 phage-like element; iron-dicitrate transporter subunit [Escherichia coli K12]  
    Pfam 28.0   (database updated : 2015-05 )
        Pfam
    PROSITE
        PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A    ABC_TRANSPORTER    PRENYLATION     

    Other Cross-Reference
        COG COG1120PH 
        EcoCyc fecE 

    MMBR References
    J Bacteriol. 1989;171(5):2626-33.
    Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli.
    Staudenmaier H, Van Hove B, Yaraghi Z, Braun V. ( 2651410 )
    J Bacteriol. 1990;172(12):6749-58.
    Novel two-component transmembrane transcription control: regulation of iron dicitrate transport in Escherichia coli K-12.
    Van Hove B, Staudenmaier H, Braun V. ( 2254251 )
    J Bacteriol. 1992;174(11):3838-9.
    Localization of the entire fec region at 97.3 minutes on the Escherichia coli K-12 chromosome.
    Veitinger S, Braun V. ( 1592838 )

    Sequences
    Amino acid
    FASTA format 
    0001 MTLRTENLTV SYGTDKVLND VSLSLPTGKI TALIGPNGCG KSTLLNCFSR LLMPQSGTVF LGDNPINMLS 
0071 SRQLARRLSL LPQHHLTPEG ITVQELVSYG RNPWLSLWGR LSAEDNARVN VAMNQTRINH LAVRRLTELS 
0141 GGQRQRAFLA MVLAQNTPVV LLDEPTTYLD INHQVDLMRL MGELRTQGKT VVAVLHDLNQ ASRYCDQLVV 
0211 MANGHVMAQG TPEEVMTPGL LRTVFSVEAE IHPEPVSGRP MCLMR
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp 
    -100                                             ggcgagaatt attcatcccc cactggagct 
-070 cccggttggc gtgctgaccg ccattatcgg tgcgccgtgg tttgtctggt tgcttgtgag aatgcgataa 
0001 atgactttac gaactgaaaa tctgacggtc agttacggga cagacaaggt acttaacgac gtttcactct 
0071 cactgccaac ggggaagatc accgccctga tcggtcctaa cggttgcggg aaatcgacgc tgttaaactg 
0141 tttttcgcgg cttttaatgc cgcagtctgg caccgtattt ctcggcgata atcccataaa tatgctctca 
0211 tcgcgccagt tggcccgcag gctttcgctg ctgcctcagc accatttaac gccagagggg atcacagtcc 
0281 aggagctggt ttcgtatggt cgtaatccct ggctgtcact ctgggggcgt ctctccgctg aagacaatgc 
0351 acgagttaat gtcgccatga accagacccg gatcaatcat cttgccgttc gtcggttaac cgagctttcc 
0421 ggcggtcagc gccagcgcgc atttctggca atggtcctgg cccagaatac gcccgttgta ttacttgatg 
0491 agccaaccac ctatcttgat atcaatcacc aggtggacct gatgcggttg atgggcgaac tccggactca 
0561 ggggaaaacg gtggtcgctg tgctgcacga ccttaatcag gctagccggt actgcgatca actggtggta 
0631 atggcaaacg gacatgttat ggcgcaaggc acaccagaag aggtgatgac cccaggattg ctgagaacag 
0701 tattcagcgt ggaagcggaa atacaccccg agccggtatc tggcaggccg atgtgcctaa tgaggtagat 
0771 tgcacaggcc gtaagaacca aaccacgact gaatgaaact ggactggcgc cagcaagcct gttcagactg 
0841 gggctgaact tttccggact ctgaaaga