|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Nucleic Acids Res. 1997;25(9):1685-93.
DNA binding and DNA bending by the MelR transcription activator protein from Escherichia coli.
Bourgerie SJ, Michan CM, Thomas MS, Busby SJ, Hyde EI.
(
9108148
)
|
|
|
Deletion
|
4
(LD)
,
OCR13,15-3 (LD 4E_CRS)
(D)
,
OCR13,15-4 (LD 4E_P/O)
(D)
,
OCR15
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
melR
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
melR
Search strains by all related name:
melR b4118 ECK4111 f302 JW4079
|
General information (Go to Linear View: )
|
|
Gene Name
|
melR
|
|
Alternative name
|
b4118,ECK4111,f302,JW4079
|
|
Location, Length
|
4,338,743 - 4,339,651
(
-
)
;
93.51
min
;
909
(bp) ,
302
(aa)
|
|
Product
|
DNA-binding transcriptional dual regulator
|
|
Operon Name
|
melR
|
|
Note
|
regulator of melibiose operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription
|
|
Function
|
regulator; Degradation of small molecules: Carbon compounds
|
|
Gene Ontology
|
GO:0003677
;
DNA binding ( melR )
GO:0003700
;
transcription factor activity ( melR )
GO:0005622
;
intracellular ( melR )
GO:0006350
;
transcription ( melR )
GO:0006355
;
regulation of transcription, DNA-dependent ( melR )
GO:0043565
;
sequence-specific DNA binding ( melR )
GO:0045449
;
regulation of transcription ( melR )
|
|
PID
|
1790559
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show simple
)
|
Entry name(Acc.no)
|
MELR_ECOLI
(
P10411
)
|
|
- Protein name
|
Melibiose operon regulatory protein.
|
|
- Synonyms
|
|
|
- Gene name
|
Name=melR; OrderedLocusNames=b4118, c5123;
|
|
- Comments
|
FUNCTION:Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site.
SIMILARITY:Contains 1 HTH araC/xylS-type DNA-binding domain.
|
|
Entry name(Acc.no)
|
Q8XDU2
(
Q8XDU2
)
|
|
- Protein name
|
Regulator of melibiose operon.
|
|
- Synonyms
|
|
|
- Gene name
|
Name=melR; OrderedLocusNames=z5720;
|
|
- Comments
|
SIMILARITY:Contains 1 HTH araC/xylS-type DNA-binding domain.
|
|
MMBR References
|
J Bacteriol. 1957;73(4):544-52.
Genetic control of raffinose utilization in Escherichia coli.
Lester G, Bonner DM.
(
13428689
)
|
Nucleic Acids Res. 1997;25:1685-1693
DNA binding and DNA bending by the MelR transcription activator protein from Escherichia coli.
Bourgerie, S. J., C. M. Michan, M. S. Thomas, S. J. Busby, and E. I. Hyde.
|
Gene. 1987;59(2-3):253-63.
Organisation of the regulatory region of the Escherichia coli melibiose operon.
Webster C, Kempsell K, Booth I, Busby S.
(
2830169
)
|
Biochem J. 1992;287 (Pt 2):493-9.
Overexpression, purification and characterization of the Escherichia coli MelR transcription activator protein.
Caswell R, Williams J, Lyddiatt A, Busby S.
(
1445207
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MNTDTFMCSS DEKQTRSPLS LYSEYQRMEI EFRAPHIMPT SHWHGQVEVN VPFDGDVEYL INNEKVNINQ
0071 GHITLFWACT PHQLTDTGTC QSMAIFNLPM HLFLSWPLDK DLINHVTHGM VIKSLATQQL SPFEVRRWQQ
0141 ELNSPNEQIR QLAIDEIGLM LKRFSLSGWE PILVNKTSRT HKNSVSRHAQ FYVSQMLGFI AENYDQALTI
0211 NDVAEHVKLN ANYAMGIFQR VMQLTMKQYI TAMRINHVRA LLSDTDKSIL DIALTAGFRS SSRFYSTFGK
0281 YVGMSPQQYR KLSQQRRQTF PG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cctcgcccct ctgggaagag ggtgaaaacc
-070 gtgctcccac tcgcagtcat cctccctcac tcctgccata attctgatat tccaggaaag agagccatcc
0001 atgaatacag atacgtttat gtgcagcagc gacgaaaaac agacccgcag cccgctgtcg ctgtattcgg
0071 aataccagcg gatggagatt gagtttcgcg caccgcatat catgcccacc agccactggc atggtcaggt
0141 cgaagtgaat gtgcctttcg atggcgatgt ggaatacctg atcaacaatg aaaaagtgaa tatcaatcag
0211 ggtcatatca cgctgttctg ggcctgtaca ccgcaccaac taacagatac cggaacctgt cagagcatgg
0281 cgatttttaa tctgccgatg catctgtttc tctcctggcc gctggataaa gacctgatta accacgtcac
0351 tcacggcatg gtgatcaaat cactggccac acagcaactt agcccgtttg aagtgcgccg ctggcagcag
0421 gaattaaaca gtccgaacga gcaaattcgc cagctcgcca ttgatgaaat tggcctgatg ctcaagcgat
0491 ttagcctctc tggctgggaa ccgattctgg tcaataaaac ctcgcgcaca cacaaaaaca gcgtctcgcg
0561 ccatgcgcaa ttttatgtta gccagatgct gggctttatt gccgaaaact atgatcaggc gctgaccatc
0631 aacgatgtgg ctgagcacgt caaacttaac gccaactatg caatggggat attccagcgg gtcatgcaat
0701 tgacgatgaa acagtacatt accgcgatgc gcatcaacca cgttcgcgcg ttactgagcg ataccgataa
0771 aagtattctc gatattgccc tgacggcagg ctttcgttca agtagtcgtt tttacagcac gttcggcaaa
0841 tatgtcggca tgtcgccgca acaataccgc aaacttagcc aacagcgccg ccagacgttt cccggctaaa
0911 gacgatatca gtatcagcca aaaaaatagt ttagccgtcg ataataagca gtgaaaataa tttaaaataa
0981 tcacataacg tattgtttat aaaactaaa
|
