MG1655
W3110
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Gene Report : dppC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Bacteriol. 1993;175(5):1452-6.
The periplasmic dipeptide permease system transports 5-aminolevulinic acid in Escherichia coli.
Verkamp E, Backman VM, Bjornsson JM, Soll D, Eggertsson G. ( 8444807 )
     Deletion 2-1 (LD)  ,  OCL10,16-3 (LD 2-1'_CRS) (D)  ,  OCL10,16-4 (LD 2-1'_P/O) (D)  ,  OCL13 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  dppC
Related strains
     Strains Search Search strains by gene name:  dppC   Search strains by all related name:  dppC b3542 ECK3529 f300 JW3511

General information  (Go to Linear View:)
 Gene Name dppC  
 Alternative name b3542,ECK3529,f300,JW3511  
 Location, Length 3,701,882 - 3,702,784 (  -  ) ;   79.79 min ; 903 (bp) ,   300 (aa) Go to Linear View
 Product dipeptide/heme transporter  
 Operon Name dppABCDF  
 Note dipeptide transport system permease protein 2; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane  
 Function transport; Protein, peptide secretion  
 Gene Ontology GO:0005215 ; transporter activity ( dppC )
GO:0005886 ; plasma membrane ( dppC )
GO:0006810 ; transport ( dppC )
GO:0006857 ; oligopeptide transport ( dppC )
GO:0015031 ; protein transport ( dppC )
GO:0015198 ; oligopeptide transporter activity ( dppC )
GO:0016020 ; membrane ( dppC )
GO:0016021 ; integral to membrane ( dppC )
 PID 1789964  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) DPPC_ECOLI ( P37315 )
    -  Protein name Dipeptide transport system permease protein dppC.  
    -  Synonyms  
    -  Gene name Name=dppC; OrderedLocusNames=b3542, c4357, z4959, ECs4422;  
    -  Comments
  • FUNCTION:Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane.
  • SUBCELLULAR LOCATION:Integral membrane protein. Inner membrane.
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.  

  •  Linear View (Whole Mode)
    View Location
       3690.0  –  3715.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP dppC (  homologous genes of other bacterias  )  
        PDB     (database updated : 2007.02.20 )
            PSI-BLAST  
        SWISS-PROT     (database updated : 2007.02.20 )
             BLAST Dipeptide transport system permease protein dppC  
             PSI-BLAST Dipeptide transport system permease protein dppC
        nr     (database updated : 2007.02.20 )
             BLAST dipeptide transport system permease protein 2 [Escherichia coli O157:H7 EDL933]  
    Pfam 28.0   (database updated : 2015-05 )
        Pfam
    PROSITE
        PROSITE MYRISTYL    BPD_TRANSP_INN_MEMBR     

    Other Cross-Reference
        COG COG1173EP 
        EcoCyc dppC 

    MMBR References
    Mol Microbiol. 1991;5(5):1035-47.
    Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein.
    Abouhamad WN, Manson M, Gibson MM, Higgins CF. ( 1956284 )
    FEMS Microbiol Lett. 1992;79(1-3):183-90.
    Expression of periplasmic binding proteins for peptide transport is subject to negative regulation by phosphate limitation in Escherichia coli.
    Smith MW, Payne JW. ( 1478454 )
    J Bacteriol. 1993;175:1452-1456
    The periplasmic dipeptide permease system transports 5-aminolevulinic acid in Escherichia coli.
    Verkamp, E., V. M. Backman, J. M. Bjornsson, D. Soll, and G. Eggertsson.

    Sequences
    Amino acid
    FASTA format
    0001 MSQVTENKVI SAPVPMTPLQ EFWHYFKRNK GAVVGLVYVV IVLFIAIFAN WIAPYNPAEQ FRDALLAPPA 
    0071 WQEGGSMAHL LGTDDVGRDV LSRLMYGARL SLLVGCLVVV LSLIMGVILG LIAGYFGGLV DNIIMRVVDI 
    0141 MLALPSLLLA LVLVAIFGPS IGNAALALTF VALPHYVRLT RAAVLVEVNR DYVTASRVAG AGAMRQMFIN 
    0211 IFPNCLAPLI VQASLGFSNA ILDMAALGFL GMGAQPPTPE WGTMLSDVLQ FAQSAWWVVT FPGLAILLTV 
    0281 LAFNLMGDGL RDALDPKLKQ 
    
    
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp
    -100                                             attgctggtg gcgacgatga ttatcctcgt 
    -070 caacttgctg gtcgatctgc tgtacggcgt ggtgaacccg cgtattcgtc ataagaagta aggggacatc 
    0001 atgtcacagg ttactgaaaa taaagtgatt agcgcaccgg tgccgatgac cccgttacag gagttctggc 
    0071 actattttaa acgcaacaaa ggcgcggtcg tcgggctggt ttacgtcgtc atcgtgctgt tcatcgcgat 
    0141 ctttgccaac tggattgcac cctataaccc ggcggaacag ttccgcgatg cactgctcgc cccgccagcc 
    0211 tggcaggaag gcggcagcat ggcgcacttg ctgggcaccg atgacgtagg ccgtgatgtg ctgtcgcgcc 
    0281 tgatgtacgg tgcgcgcctg tcgctgctgg ttggctgtct ggtagttgtg ttatcgctga ttatgggcgt 
    0351 tattctcggc ctgatcgccg gttactttgg cggcctggtc gataacatca ttatgcgcgt ggtcgatatc 
    0421 atgctggcgc tgccaagtct gctgctggcg ctggtgctgg tggcaatttt cggcccgtcg attggtaacg 
    0491 ccgcgctggc actgaccttc gttgccttgc cgcactatgt gcgcttaacc cgcgccgccg tgctggtgga 
    0561 agttaaccgc gattacgtca ccgcgtctcg cgtggcgggt gccggggcga tgcgtcagat gtttattaac 
    0631 atcttcccga actgccttgc gccgctgatt gttcaggcgt cgctcggttt ctctaacgcc attctcgata 
    0701 tggctgctct tggtttcctc ggcatggggg cacagccgcc aacgcctgag tggggcacca tgctctccga 
    0771 cgtgttgcag ttcgcgcaaa gcgcctggtg ggtcgtgacc ttcccgggtc tggcgatcct gctgacggtg 
    0841 ctggcattta acctgatggg tgacggtctg cgtgacgcgc tcgatcccaa actgaagcag taagaggttc 
    0911 gagatggcgt tattaaatgt agataaatta tcggtgcatt tcggcgacga aagcgcgccg ttccgcgccg 
    0981 tagaccgcat cagctacagc gta