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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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DE(bioH-asd)29
,
OCL18,19-3
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
glpR
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Related strains
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Strains Search
|
Search strains by gene name:
glpR
Search strains by all related name:
glpR b3423 ECK3409 f252 JW3386
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General information (Go to Linear View: )
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Gene Name
|
glpR
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Alternative name
|
b3423,ECK3409,f252,JW3386
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Location, Length
|
3,557,870 - 3,558,628
(
-
)
;
76.68
min
;
759
(bp) ,
252
(aa)
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Product
|
DNA-binding transcriptional repressor
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Operon Name
|
glpEGR
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Note
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repressor of the glp operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0009061 - anaerobic respiration; GO_process: GO:0006350 - transcription
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Function
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regulator; Energy metabolism, carbon: Anaerobic respiration
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Gene Ontology
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GO:0003677
;
DNA binding ( glpR )
GO:0003700
;
transcription factor activity ( glpR )
GO:0005515
;
protein binding ( glpR )
GO:0005622
;
intracellular ( glpR )
GO:0006071
;
glycerol metabolic process ( glpR )
GO:0006350
;
transcription ( glpR )
GO:0006355
;
regulation of transcription, DNA-dependent ( glpR )
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PID
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1789829
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EC number
(KEGG Pathway)
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
|
glpR
(
EG10400
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
|
GLPR_ECOLI
(
P09392
)
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- Protein name
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Glycerol-3-phosphate regulon repressor.
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- Synonyms
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- Gene name
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Name=glpR; OrderedLocusNames=b3423, SF3445, S4319;
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- Comments
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FUNCTION:Repressor of the glycerol-3-phosphate regulon.
SIMILARITY:Contains 1 HTH deoR-type DNA-binding domain.
CAUTION:Ref.2 sequence differs from that shown due to frameshifts.
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Entry name(Acc.no)
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Q8FCS6
(
Q8FCS6
)
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- Protein name
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Glycerol-3-phosphate regulon repressor.
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- Synonyms
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- Gene name
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Name=glpR; OrderedLocusNames=c4200;
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- Comments
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SIMILARITY:Contains 1 HTH deoR-type DNA-binding domain.
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Entry name(Acc.no)
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Q8X4P4
(
Q8X4P4
)
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- Protein name
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Repressor of the glp operon.
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- Synonyms
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- Gene name
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Name=glpR; OrderedLocusNames=z4781;
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- Comments
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SIMILARITY:Contains 1 HTH deoR-type DNA-binding domain.
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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glpR
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
|
Chain A, Smc Head Domain From Thermotoga Maritima
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Glycerol-3-phosphate regulon repressor
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PSI-BLAST
|
Glycerol-3-phosphate regulon repressor
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nr
(database updated :
2007.02.20
)
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BLAST
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COG1349: Transcriptional regulators of sugar metabolism [Shigella dysenteriae 1012]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
HTH_DEOR_FAMILY
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MMBR References
|
J Bacteriol. 1966;92(4):1083-9.
Location of the maltose A and B loci on the genetic map of Escherichia coli.
Schwartz M.
(
5332865
)
|
Mol Gen Genet. 1986;202(3):488-92.
Physical and genetic structure of the glpD-malT interval of the Escherichia coli K-12 chromosome. Identification of two new structural genes of the glp-regulon.
Schweizer H, Sweet G, Larson TJ.
(
3012272
)
|
J Bacteriol. 1985;161(2):563-6.
Repressor for the sn-glycerol-3-phosphate regulon of Escherichia coli K-12: cloning of the glpR gene and identification of its product.
Schweizer H, Boos W, Larson TJ.
(
3881401
)
|
J Bacteriol. 1996;178:7080-7089
Repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K-12: primary structure and identification of the DNA-binding domain.
Zeng, G., S. Ye, and T. J. Larson.
|
Nucleic Acids Res. 1988;16(15):7732
Nucleotide sequence of the glpR gene encoding the repressor for the glycerol-3-phosphate regulon of Escherichia coli K12.
Choi YL, Kawase S, Nishida T, Sakai H, Komano T, Kawamukai M, Utsumi R, Kohara Y, Akiyama K.
(
3045764
)
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| Sequences |
Amino acid
FASTA format
|
0001 MKQTQRHNGI IELVKQQGYV STEELVEHFS VSPQTIRRDL NELAEQNLIL RHHGGAALPS SSVNTPWHDR
0071 KATQTEEKER IARKVAEQIP NGSTLFIDIG TTPEAVAHAL LNHSNLRIVT NNLNVANTLM VKEDFRIILA
0141 GGELRSRDGG IIGEATLDFI SQFRLDFGIL GISGIDSDGS LLEFDYHEVR TKRAIIENSR HVMLVVDHSK
0211 FGRNAMVNMG SISMVDAVYT DAPPPVSVMQ VLTDHHIQLE LC
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gcgaacggag cacacatcgc cgggttagcc
-070 gtgggtttag cgatggcttt tgttgattcg ctcaatgcgc gaaaacgaaa ataattccag ggatttataa
0001 atgaaacaaa cacaacgtca caacggtatt atcgaactgg ttaaacagca gggttatgtc agtaccgaag
0071 agctggtaga gcatttctcc gtcagcccgc agactattcg ccgcgacctc aatgagctgg cggagcaaaa
0141 cctgatcctg cgccatcatg gcggtgcggc gctgccttcc agttcggtta acacgccgtg gcacgatcgc
0211 aaggccaccc agaccgaaga aaaagagcgc atcgcccgca aagtggcgga gcaaatcccc aatggctcga
0281 cgctgtttat cgatatcggc accacgccgg aagcggtagc gcacgcactg ctcaatcaca gcaatttgcg
0351 cattgtcacc aacaatctca acgttgctaa cacgttgatg gtaaaagaag attttcgcat cattctcgcc
0421 ggtggcgaat tacgcagccg cgatggcggg atcattggcg aagcgacgct cgattttatc tcccagttcc
0491 gccttgattt cggcattctg gggataagcg gcatcgatag cgacggctcg ctgctggagt tcgattacca
0561 cgaagttcgc accaaacgcg ccattattga gaactcgcgc cacgttatgc tggttgtcga tcactcgaaa
0631 tttggccgta acgcgatggt caatatgggc agcatcagca tggtagatgc cgtctacacc gacgccccgc
0701 cgccagtaag cgtgatgcag gtgctgacgg accaccatat tcaactggag ctgtgctgat cctgcacggc
0771 ttcccacgtc agaccaaaac gcgccaggta tttgcgtagc cgatccgcgt cattgacgct ggctttgccc
0841 tggcgcgaaa cgtcaaaaa
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