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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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16-1-2
(LD)
,
DE(sbcB-rfb)202
,
OCL74-2,75-5 (LD 16-1-2_CRS)
(D)
,
OCL74-2,75-6 (LD 16-1-2_P/O)
(D)
,
OCL74-3
(D)
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Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
udk
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Related strains
|
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Strains Search
|
Search strains by gene name:
udk
Search strains by all related name:
udk b2066 ECK2060 JW2051
|
General information (Go to Linear View: )
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Gene Name
|
udk
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Alternative name
|
b2066,ECK2060,JW2051
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Location, Length
|
2,140,331 - 2,140,972
(
-
)
;
46.13
min
;
642
(bp) ,
213
(aa)
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Product
|
uridine/cytidine kinase
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Operon Name
|
udk-dcd
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Note
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GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion
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Function
|
enzyme; Central intermediary metabolism: Nucleotide interconversions
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Gene Ontology
|
GO:0000166
;
nucleotide binding ( udk )
GO:0004849
;
uridine kinase activity ( udk )
GO:0005524
;
ATP binding ( udk )
GO:0005737
;
cytoplasm ( udk )
GO:0008152
;
metabolic process ( udk )
GO:0008655
;
pyrimidine salvage ( udk )
GO:0016301
;
kinase activity ( udk )
GO:0016740
;
transferase activity ( udk )
GO:0016773
;
phosphotransferase activity, alcohol group as acceptor ( udk )
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PID
|
87082034
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EC number
(KEGG Pathway)
|
2.7.1.48
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SWISS-PROT
(
Show simple
)
|
Entry name(Acc.no)
|
URK_ECOLI
(
P31218
;
P78085; Q8X7L3
)
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- Protein name
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Uridine kinase
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- Synonyms
|
EC 2.7.1.48, Uridine monophosphokinase, Cytidine monophosphokinase
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- Gene name
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OrderedLocusNames=b2066, c2593, z3234, ECs2873, SF2130, S2254;
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- Comments
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CATALYTIC ACTIVITY:ATP + uridine = ADP + UMP.
CATALYTIC ACTIVITY:ATP + cytidine = ADP + CMP.
PATHWAY:Pyrimidine salvage pathway.
SUBUNIT:Homotetramer.
SUBCELLULAR LOCATION:Cytoplasmic.
SIMILARITY:Belongs to the uridine kinase family.
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MMBR References
|
J Bacteriol. 1983;154(1):72-5.
Mapping of the gene for cytidine deaminase (cdd) in Escherichia coli K-12.
Josephsen J, Hammer-Jespersen K, Hansen TD.
(
6339482
)
|
J Bacteriol. 1976;126(2):999-1001.
Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene.
Neuhard J, Thomassen E.
(
177407
)
|
J Bacteriol. 1993;175(17):5742-3.
Location of the udk gene on the physical map of Escherichia coli.
Neuhard J, Tarpo L.
(
8366067
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MTDQSHQCVI IGIAGASASG KSLIASTLYR ELREQVGDEH IGVIPEDCYY KDQSHLSMEE RVKTNYDHPS
0071 AMDHSLLLEH LQALKRGSAI DLPVYSYVEH TRMKETVTVE PKKVIILEGI LLLTDARLRD ELNFSIFVDT
0141 PLDICLMRRI KRDVNERGRS MDSVMAQYQK TVRPMFLQFI EPSKQYADII VPRGGKNRIA IDILKAKISQ
0211 FFE
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ctattcgact ggtatcagac ggatgaaatc
-070 cctataattg ccgcgtttgg cgcttcgtcg cccccttcct aacatccagg ttaatcaggt cgctaaatat
0001 atgactgatc agtctcatca gtgcgtcatt atcggtatcg ctggcgcatc ggcttccggc aagagtctta
0071 ttgccagtac cctttatcgt gaattgcgtg agcaagtcgg tgatgaacac atcggcgtaa ttcccgaaga
0141 ctgctattac aaagatcaaa gccatctgtc gatggaagaa cgcgttaaga ccaactacga ccatcccagc
0211 gcgatggatc acagtctgct gcttgagcat ttacaagcgt tgaaacgcgg ctcggcaatt gacctgccgg
0281 tttacagcta tgttgaacat acgcgtatga aagaaacggt gacggttgag ccgaagaagg tcatcattct
0351 cgaaggcatt ttgttgctga cggatgcgcg tttgcgtgac gaacttaact tctccatttt cgttgatacc
0421 ccgctggata tctgcctgat gcgccgcatc aagcgtgacg ttaacgagcg tgggcgttca atggattcag
0491 tgatggcgca atatcaaaaa accgtgcgcc cgatgttcct gcaattcatt gagccttcta aacaatatgc
0561 ggacattatc gtgccgcgcg gcgggaaaaa ccgcatcgcg atcgatatat tgaaagcgaa aataagtcag
0631 ttctttgaat aagcttgata aattgtgtac cgttcagtga taacctagta tgcccttgac gtaattggcg
0701 ttaagggagt gatgcgcgaa aggagaaaat gccatgcgtc tg
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