MG1655
W3110
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Gene Report : lsrA
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion 20 (LD)  ,  DE(PLK1608)  ,  OCR70,L90-6 (LD 20-1_P/O & 20-2TC) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  lsrA
Related strains
     Strains Search Search strains by gene name:  lsrA   Search strains by all related name:  lsrA b1513 ECK1506 ego JW1506 lsrA o511 o511a ydeX

General information  (Go to Linear View:)
 Gene Name lsrA  
 Alternative name b1513,ECK1506,ego,JW1506,lsrA,o511,o511a,ydeX  
 Location, Length 1,599,514 - 1,601,049 (  +  ) ;   34.47 min ; 1536 (bp) ,   511 (aa) Go to Linear View
 Product autoinducer 2 import ATP-binding protein  
 Operon Name lsrACDBFG-tam  
 Note autoinducer-2 (AI-2)-transporting ATPase; GO_component: GO:0005737 - cytoplasm  
 Function hydrolyzes ATP to provide energy for the uptake of autoinducer-2 (AI-2) (organism: Escherichia coli MG1655)  
 Gene Ontology GO:0000166 ; nucleotide binding ( ego )
GO:0005515 ; protein binding ( ego )
GO:0005524 ; ATP binding ( ego )
GO:0006810 ; transport ( ego )
GO:0016887 ; ATPase activity ( ego )
GO:0017111 ; nucleoside-triphosphatase activity ( ego )
 PID 1787792  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) EGO_ECOLI ( P77257 ; P76879 )
    -  Protein name Putative ABC transporter ATP-binding protein ego  
    -  Synonyms EGO10A  
    -  Gene name Name=ego; OrderedLocusNames=b1513;  
    -  Comments
  • FUNCTION:Probably part of a binding-protein-dependent transport system ego/ydeYZ. Probably responsible for energy coupling to the transport system. This protein is essential for aerobic growth.
  • SIMILARITY:Belongs to the ABC transporter family. MglA subfamily.  

    •  Linear View (Whole Mode)
    View Location
       1590.0  –  1615.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP lsrA (  homologous genes of other bacterias  )  
        PDB     (database updated : 2007.02.20 )
             PSI-BLAST Chain A, Rnase-L Inhibitor  
        SWISS-PROT     (database updated : 2007.02.20 )
             BLAST Putative ABC transporter ATP-binding protein ego  
             PSI-BLAST Putative ribose/galactose/methyl galactoside import ATP-binding protein
        nr     (database updated : 2007.02.20 )
             BLAST fused AI2 transporter subunits of ABC superfamily: ATP-binding components [Escherichia coli K12]  
    Pfam 28.0   (database updated : 2015-05 )
        Pfam
    PROSITE
        PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A    ABC_TRANSPORTER     

    Other Cross-Reference
        COG COG1129G 
        EcoCyc lsrA 

    Sequences
    Amino acid
    FASTA format 
    0001 MQTSDTRALP LLCARSVYKQ YSGVNVLKGI DFTLHQGEVH ALLGGNGAGK STLMKIIAGI TPADSGTLEI 
0071 EGNNYVRLTP VHAHQLGIYL VPQEPLLFPS LSIKENILFG LAKKQLSMQK MKNLLAALGC QFDLHSLAGS 
0141 LDVADRQMVE ILRGLMRDSR ILILDEPTAS LTPAETERLF SRLQELLATG VGIVFISHKL PEIRQIADRI 
0211 SVMRDGTIAL SGKTSELSTD DIIQAITPAV REKSLSASQK LWLELPGNRP QHAAGTPVLT LENLTGEGFR 
0281 NVSLTLNAGE ILGLAGLVGA GRTELAETLY GLRTLRGGRI MLNGKEINKL STGERLLRGL VYLPEDRQSS 
0351 GLNLDASLAW NVCALTHNLR GFWAKTAKDN ATLERYRRAL NIKFNQPEQA ARTLSGGNQQ KILIAKCLEA 
0421 SPQVLIVDEP TRGVDVSARN DIYQLLRSIA AQNVAVLLIS SDLEEIELMA DRVYVMHQGE ITHSALTERD 
0491 INVETIMRVA FGDSQRQEAS C
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp 
    -100                                             TTCGTCGGAA ATATGTGCAA TGTCCACCTA 
-070 AGGTTATGAA CAAATTAAAA GCAGAAATAC ATTTGTTCAA AACTCACCTG CAAAACTGAA CGGGGGAAAT 
0001 atgcaaacga gtgatacccg cgcgttaccg ctactttgcg cccgctcggt ttataaacag tattcagggg 
0071 tcaatgtcct gaaaggcatc gattttacgt tgcatcaggg ggaggtccac gccctgctcg gcggcaatgg 
0141 tgccggtaaa tcgacgttaa tgaagattat tgccggtatt acccctgctg atagcggtac gctggagatt 
0211 gagggcaaca actacgtcag attaacgcca gttcatgctc atcagctggg tatttatctc gttccccagg 
0281 aaccgctgct tttcccaagc ctgtcgataa aagaaaacat cctgtttggg ctggcaaaaa aacagctctc 
0351 catgcagaaa atgaagaact tgctggcggc gctgggctgc cagtttgatc tgcatagtct ggcaggatcg 
0421 ctggatgtcg ccgatcgcca aatggtggaa atcctccgcg ggctgatgcg cgactcgcgg attctgatcc 
0491 tcgatgaacc taccgcctcg cttacccctg cggaaaccga acgcttgttt agtcgcttgc aagagctgct 
0561 tgctactggc gtgggtattg tttttatctc gcataagctg ccggaaattc gccagattgc cgatcgaatt 
0631 agcgtgatgc gcgacggaac catcgcctta agcggcaaaa ccagcgaact gtctaccgac gacattattc 
0701 aggccatcac cccagcggta cgggaaaaat cgctctctgc cagccaaaaa ttatggctgg agttacctgg 
0771 taaccgccca caacatgccg ccggaacgcc ggtgctgaca ctggaaaatc tgaccggcga aggtttcagg 
0841 aatgtcagcc tgacgctcaa tgccggagaa attctgggcc tggctgggct ggtgggggcc ggacgcacag 
0911 aactggccga gacgctctat ggtctgcgta ctttgcgtgg cggacgcatt atgctgaatg gtaaagagat 
0981 caataaatta tccactggag aacgtttact gcgcggtctg gtttatctgc cggaagatcg ccagtcatcc 
1051 ggactgaatc tcgatgcttc gctggcctgg aacgtctgcg cccttactca taaccttcgt ggattctggg 
1121 cgaaaaccgc gaaagataat gccaccctgg aacgttatcg tcgggcgctg aatattaaat tcaaccaacc 
1191 ggaacaagct gcacggacat tatccggtgg caaccagcaa aaaatcctca ttgccaaatg cttggaagct 
1261 tcgccgcaag tattgattgt cgatgagccg acgcgcggcg tggatgtctc ggcccgtaat gatatctacc 
1331 agctgttgcg cagcatcgcc gcacaaaatg tggctgtgct gcttatctcc tccgacctgg aagagatcga 
1401 actgatggca gatcgtgtgt atgtgatgca tcagggcgaa attacccact ctgcactgac cgagcgcgat 
1471 attaatgtcg agactattat gcgcgttgcc ttcggcgata gtcagcgtca ggaggcgtca tgctgaAGTT 
1541 TATTCAGAAC AACCGTGAAA TCACGGCACT GCTGGCGGTG GTGCTGCTGT TTGTATTACC CGGTTTTCTC 
1611 GACCGCCAGT ATTTAAGTGT GCAAAC