MG1655
W3110
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Gene Report : sapB
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion 20 (LD)  ,  OCR70 (D)  ,  OCR70,L90-5 (LD 20-1_P/O) (D)  ,  OCR70,L90-6 (LD 20-1_P/O & 20-2TC) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  sapB
Related strains
     Strains Search Search strains by gene name:  sapB   Search strains by all related name:  sapB b1293 ECK1288 f321 JW1286

General information  (Go to Linear View:)
 Gene Name sapB  
 Alternative name b1293,ECK1288,f321,JW1286  
 Location, Length 1,352,529 - 1,353,494 (  -  ) ;   29.15 min ; 966 (bp) ,   321 (aa) Go to Linear View
 Product antimicrobial peptide transport ABC transporter permease  
 Operon Name sapABCDF  
 Note homolog of Salmonella peptide transport permease protein; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane  
 Function putative transport; Not classified  
 Gene Ontology GO:0005215 ; transporter activity ( sapB )
GO:0005886 ; plasma membrane ( sapB )
GO:0006810 ; transport ( sapB )
GO:0006857 ; oligopeptide transport ( sapB )
GO:0015031 ; protein transport ( sapB )
GO:0015198 ; oligopeptide transporter activity ( sapB )
GO:0016020 ; membrane ( sapB )
GO:0016021 ; integral to membrane ( sapB )
 PID 1787550  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) SAPB_ECOLI ( Q47623 ; P76838 )
    -  Protein name Peptide transport system permease protein sapB.  
    -  Synonyms  
    -  Gene name Name=sapB; OrderedLocusNames=b1293, z2496, ECs1870;  
    -  Comments
  • FUNCTION:Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
  • SUBCELLULAR LOCATION:Integral membrane protein. Inner membrane (Potential).
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.  
    •   botton Entry name(Acc.no) Q8FHS8 ( Q8FHS8 )
        -  Protein name Peptide transport system permease protein sapB.  
        -  Synonyms  
        -  Gene name Name=sapB; OrderedLocusNames=c1770;  
        -  Comments
  • FUNCTION:Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity).
  • SUBCELLULAR LOCATION:Integral membrane protein (By similarity).
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family.  

    •  Linear View (Whole Mode)
    View Location
       1340.0  –  1365.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP sapB (  homologous genes of other bacterias  )  
        PDB     (database updated : 2007.02.20 )
            PSI-BLAST  
        SWISS-PROT     (database updated : 2007.02.20 )
             BLAST Peptide transport system permease protein sapB  
             PSI-BLAST Peptide transport system permease protein sapB
        nr     (database updated : 2007.02.20 )
             BLAST homolog of Salmonella peptide transport permease protein [Escherichia coli O157:H7 EDL933]  
    Pfam 28.0   (database updated : 2015-05 )
        Pfam
    PROSITE
        PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL     

    Other Cross-Reference
        COG COG4168V 
        EcoCyc sapB 

    MMBR References
    GenBank submission U08190. 1994

    Bergler, H., et al.
    Personal communication.

    Wu, H. C., and K. Rudd.

    Sequences
    Amino acid
    FASTA format 
    0001 MIIFTLRRIL LLIVTLFLLT FVGFSLSYFT PHAPLQGASL WNAWVFWFNG LIHWDFGVSS INGQPIAEQL 
0071 KEVFPATMEL CILAFGFALI VGIPVGMIAG ITRHKWQDNL INAIALLGFS IPVFWLALLL TLFCSLTLGW 
0141 LPVSGRFDLL YEVKPITGFA LIDAWLSDSP WRDEMIMSAI RHMILPVITL SVAPTTEVIR LMRISTIEVY 
0211 DQNYVKAAAT RGLSRFTILR RHVLHNALPP VIPRLGLQFS TMLTLAMITE MVFSWPGLGR WLINAIRQQD 
0281 YAAISAGVMV CGSLVIIVNV ISDILGAMAN PLKHKEWYAL R
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp 
    -100                                             aggcctatcg gtacgatatc aaaggtctgg 
-070 tacttagccc gtttggtaac gcctcctttg ctggggtgta tcgcgagaaa caggatgagg tgaaaaaacc 
0001 atgattatct tcaccttacg ccgcattttg ttattgattg tcaccttgtt cctgctgacc ttcgttggct 
0071 tcagcttgag ctatttcacc cctcatgcgc cgttacaagg cgcgtcactg tggaatgcct gggtgttctg 
0141 gtttaacggc ctgatccact gggattttgg tgtttccagc attaacggtc aaccgattgc cgaacagtta 
0211 aaagaggtct tcccggcgac gatggaactg tgcatcctcg ccttcggttt tgcgctgatt gttggcatcc 
0281 ccgtggggat gattgccggg attacgcgcc ataagtggca ggataacttg atcaacgcca tcgccttact 
0351 gggcttttca atcccggtgt tctggctggc gcttctgttg acgctgtttt gttcactcac gctaggttgg 
0421 ttgcccgttt cagggcgttt cgatctgctc tacgaagtga aaccgattac cggttttgcg ttgattgatg 
0491 cctggctttc ggactcacca tggcgggatg aaatgatcat gagcgcaatc cgccatatga tattgcccgt 
0561 gatcaccctg tcggttgcgc caacaactga agtgatccgc ctgatgcgta tcagcactat cgaagtgtat 
0631 gaccagaact atgtaaaagc ggcggcgacc cgcggtttgt cgcgctttac tattttgcgt cgccacgttc 
0701 tgcataacgc gttaccgccg gttattcctc gcctgggctt acagttttcc accatgctga cgctggcgat 
0771 gatcaccgaa atggttttta gctggccggg tttagggcgc tggttaatta acgccatccg ccagcaggat 
0841 tacgcagcca tttccgccgg agtgatggtg tgtggctcac tggtcattat tgttaacgtg atttctgata 
0911 ttttgggtgc catggctaac cctctgaaac ataaggaatg gtatgcctta cgatagcgta tacagcgaaa 
0981 agcgcccgcc gggcacgctg cgtaccgcct ggcgcaaatt ttatagtgac gcctctgcga tggtcggcct 
1051 gtacggctgc gcgggg