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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCR63
(D)
|
|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
potC
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Related strains
|
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Strains Search
|
Search strains by gene name:
potC
Search strains by all related name:
potC b1124 ECK1110 JW1110
|
General information (Go to Linear View: )
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Gene Name
|
potC
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|
Alternative name
|
b1124,ECK1110,JW1110
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|
Location, Length
|
1,182,049 - 1,182,843
(
-
)
;
25.48
min
;
795
(bp) ,
264
(aa)
|
|
Product
|
polyamine transporter subunit
|
|
Operon Name
|
potABCD
|
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Note
|
spermidine/putrescine transport system permease; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006596 - polyamine biosynthetic process; GO_process: GO:0009310 - amine catabolic process
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Function
|
transport; Transport of small molecules: Amino acids, amines
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Gene Ontology
|
GO:0005215
;
transporter activity ( potC )
GO:0005886
;
plasma membrane ( potC )
GO:0006810
;
transport ( potC )
GO:0016020
;
membrane ( potC )
GO:0016021
;
integral to membrane ( potC )
|
|
PID
|
1787368
|
EC number
(KEGG Pathway)
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SWISS-PROT
(
Show simple
)
|
Entry name(Acc.no)
|
POTC_ECOLI
(
P23859
)
|
|
- Protein name
|
Spermidine/putrescine transport system permease protein potC.
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- Synonyms
|
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- Gene name
|
Name=potC; OrderedLocusNames=b1124, c1399, z1763, ECs1500;
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- Comments
|
FUNCTION:Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.
SUBCELLULAR LOCATION:Integral membrane protein. Inner membrane (Potential).
SIMILARITY:Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
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Homology Analysis
|
|
BLAST
|
|
Bacteria
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|
GTOP
|
potC
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
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BLAST
|
Spermidine/putrescine transport system permease protein potC
|
|
PSI-BLAST
|
Spermidine/putrescine transport system permease protein potC
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
spermidine/putrescine ABC transporter membrane component [Escherichia coli O157:H7 EDL933]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
BPD_TRANSP_INN_MEMBR
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MMBR References
|
J Biol Chem. 1991;266:20928-20933
Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.
Furuchi, T., K. Kashiwagi, H. Kobayashi, and K. Igarashi.
|
J Biol Chem. 1993;268:19358-19363
Functions of potA and potD proteins in spermidine-preferential uptake system in Escherichia coli.
Kashiwagi, K., S. Miyamoto, E. Nukui, H. Kobayashi, and K. Igarashi.
|
J Bacteriol. 1993;175(23):7745-6.
Physical mapping of the Escherichia coli pepT and potABCD genes.
Lombardo MJ, Miller CG, Rudd KE.
(
8244951
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MIGRLLRGGF MTAIYAYLYI PIIILIVNSF NSSRFGINWQ GFTTKWYSLL MNNDSLLQAA QHSLTMAVFS
0071 ATFATLIGSL TAVALYRYRF RGKPFVSGML FVVMMSPDIV MAISLLVLFM LLGIQLGFWS LLFSHITFCL
0141 PFVVVTVYSR LKGFDVRMLE AAKDLGASEF TILRKIILPL AMPAVAAGWV LSFTLSMDDV VVSSFVTGPS
0211 YEILPLKIYS MVKVGVSPEV NALATILLVL SLVMVIASQL IARDKTKGNT GDVK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttggtgcagc taccagcatt acgctgacta
-070 tcgtaatggg cctgatgttg ctggtttact ggcgcgcttc tcgtttgctg aataagaagg tggaactcga
0001 atgatcggtc gactgcttcg cggcggtttt atgaccgcta tctacgcgta cctgtatatc ccaatcatta
0071 ttttgattgt gaactccttt aacagctcgc gctttggcat caactggcag ggctttacca ccaaatggta
0141 tagcctgctg atgaacaacg acagcctgtt acaggcagcg cagcattcac taacaatggc ggtgttttcg
0211 gcgacgtttg ctacgcttat cggttcactg acggcagttg cgctgtaccg ttatcgcttt cgtggtaagc
0281 cgttcgttag cggaatgctg tttgtggtga tgatgtcacc agatatcgtg atggcgattt cgctgctggt
0351 gctgtttatg ctgctgggta ttcagcttgg cttctggtcg ctgctgttct cgcatatcac cttctgcctg
0421 ccatttgtgg tggtgacggt gtattcgcgc ctgaaaggtt ttgacgtgcg aatgctggaa gcggcgaaag
0491 atctcggtgc cagcgaattt accattctgc gaaaaatcat tctgccactg gcaatgccag cggtggcggc
0561 gggctgggtg ttaagcttta ccctgtcgat ggacgatgtg gtagtttctt cgttcgtcac cggaccaagt
0631 tatgaaattc tgccgttaaa aatttattcg atggtcaaag tcggcgtatc gccggaagtt aacgcgctgg
0701 caaccatatt actggtgctg tcgctggtga tggttattgc cagccagctt attgctcgtg ataaaacgaa
0771 aggtaacaca ggggacgtta aatgaaaaaa tggtcacgcc acctgctcgc ggcgggtgct ctggcactgg
0841 gcatgagcgc cgctcacgcc gatgacaaca acacgctgta tttctacaac tggac
|
