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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Nat Cell Biol. 2000;2(4):212-8.
A new ABC transporter mediating the detachment of lipid-modified proteins from membranes.
Yakushi T, Masuda K, Narita S, Matsuyama S, Tokuda H.
(
10783239
)
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Deletion
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OCR62-6
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
lolD
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Related strains
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Strains Search
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Search strains by gene name:
lolD
Search strains by all related name:
lolD b1117 ECK1103 JW5162 o228 o228b ycfV
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General information (Go to Linear View: )
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Gene Name
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lolD
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Alternative name
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b1117,ECK1103,JW5162,o228,o228b,ycfV
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Location, Length
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1,175,842 - 1,176,543
(
+
)
;
25.34
min
;
702
(bp) ,
233
(aa)
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Product
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outer membrane-specific lipoprotein transporter subunit
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Operon Name
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lolCDE
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Note
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putative ATP-binding component of a transport system; GO_component: GO:0005737 - cytoplasm
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Function
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putative transport; Not classified
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Gene Ontology
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GO:0000166
;
nucleotide binding ( lolD )
GO:0005524
;
ATP binding ( lolD )
GO:0005886
;
plasma membrane ( lolD )
GO:0006810
;
transport ( lolD )
GO:0016020
;
membrane ( lolD )
GO:0016787
;
hydrolase activity ( lolD )
GO:0016887
;
ATPase activity ( lolD )
GO:0017111
;
nucleoside-triphosphatase activity ( lolD )
GO:0042953
;
lipoprotein transport ( lolD )
GO:0042954
;
lipoprotein transporter activity ( lolD )
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PID
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87081834
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EC number
(KEGG Pathway)
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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lolD
(
EG13440
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
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LOLD_ECOLI
(
P75957
;
Q9R7N6
)
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- Protein name
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Lipoprotein releasing system ATP-binding protein lolD.
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- Synonyms
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- Gene name
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Name=lolD; OrderedLocusNames=b1117;
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- Comments
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FUNCTION:Part of the ABC transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, lolA. Responsible for the formation of the lolA-lipoprotein complex in an ATP-dependent manner. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of lolA.
SUBUNIT:The complex is composed of two ATP-binding proteins (lolD) and two transmembrane proteins (lolC and lolE).
SUBCELLULAR LOCATION:Inner membrane-associated.
SIMILARITY:Belongs to the ABC transporter family. Lipoprotein translocase (TC 3.A.1.125) subfamily.
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Entry name(Acc.no)
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LOLD_ECOL6
(
Q8FIM7
)
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- Protein name
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Lipoprotein releasing system ATP-binding protein lolD.
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- Synonyms
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- Gene name
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Name=lolD; OrderedLocusNames=c1392;
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- Comments
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FUNCTION:Part of the ABC transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, lolA. Responsible for the formation of the lolA-lipoprotein complex in an ATP-dependent manner (By similarity).
SUBUNIT:The complex is composed of two ATP-binding proteins (lolD) and two transmembrane proteins (lolC and lolE) (Probable).
SUBCELLULAR LOCATION:Inner membrane-associated (By similarity).
SIMILARITY:Belongs to the ABC transporter family. Lipoprotein translocase (TC 3.A.1.125) subfamily.
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Entry name(Acc.no)
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LOLD_ECO57
(
Q8X8E3
)
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- Protein name
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Lipoprotein releasing system ATP-binding protein lolD.
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- Synonyms
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- Gene name
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Name=lolD; OrderedLocusNames=z1758, ECs1495;
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- Comments
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FUNCTION:Part of the ABC transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, lolA. Responsible for the formation of the lolA-lipoprotein complex in an ATP-dependent manner (By similarity).
SUBUNIT:The complex is composed of two ATP-binding proteins (lolD) and two transmembrane proteins (lolC and lolE) (Probable).
SUBCELLULAR LOCATION:Inner membrane-associated (By similarity).
SIMILARITY:Belongs to the ABC transporter family. Lipoprotein translocase (TC 3.A.1.125) subfamily.
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| Sequences |
Amino acid
FASTA format
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0001 MNKILLQCDN LCKRYQEGSV QTDVLHNVSF SVGEGEMMAI VGSSGSGKST LLHLLGGLDT PTSGDVIFNG
0071 QPMSKLSSAA KAELRNQKLG FIYQFHHLLP DFTALENVAM PLLIGKKKPA EINSRALEML KAVGLDHRAN
0141 HRPSELSGGE RQRVAIARAL VNNPRLVLAD EPTGNLDARN ADSIFQLLGE LNRLQGTAFL VVTHDLQLAK
0211 RMSRQLEMRD GRLTAELSLM GAE
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GTCATTGTTA TTGCGCTGGT GGCGATGGCT
-070 ATCGCGCTGC TGTCTACGCT TTACCCTTCA TGGCGCGCTG CCGCCACTCA ACCCGCTGAG GCTTTACGTT
0001 atgaataaga tcctgttgca atgcgacaac ctgtgcaaac gctatcagga aggcagtgtg caaaccgatg
0071 tgctgcacaa tgtcagtttc agcgtcggcg aaggtgaaat gatggcgatc gtcggtagct ctggttccgg
0141 taaaagtacc ttgctgcacc tgctgggcgg gctggatacg ccaacctccg gcgatgtgat ttttaatggt
0211 cagccaatga gcaaactgtc gtcggcagcg aaagctgaac tgcgcaacca gaagctgggc tttatttatc
0281 agtttcacca cctgctgccg gattttaccg ccctggaaaa cgtggctatg ccgctgctga ttggcaagaa
0351 aaagcccgct gaaatcaaca gccgtgcact tgagatgtta aaagcggtgg ggctggatca tcgtgcgaat
0421 caccgcccat ctgaactttc tggcggcgaa cgccagcgtg tggcgattgc ccgtgcgctg gtgaataacc
0491 cgcgcctggt actggcggat gaacctaccg gtaacctcga tgcgcgtaac gccgacagca tcttccagtt
0561 gcttggggaa ttgaatcgct tgcagggcac cgccttcctg gtggttactc acgacctgca actggcgaaa
0631 cgtatgagcc gccagttaga aatgcgtgat ggtcgtctga cggcggaact gagcctgatg ggggcggagt
0701 aaTGGCGATG CCTTTATCGT TATTAATTGG CCTGCGTTTT AGTCGCGGAC GGCGGCGCGG CGGCATGGTG
0771 TCGCTGATCT CCGTTATTTC TACCATTGGC AT
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