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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Mol Microbiol. 1990;4(3):427-37.
Sequence of the fhuE outer-membrane receptor gene of Escherichia coli K12 and properties of mutants.
Sauer M, Hantke K, Braun V.
(
2162465
)
|
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Deletion
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OCR62-1
(D)
,
OCR62-6
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
fhuE
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Related strains
|
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Strains Search
|
Search strains by gene name:
fhuE
Search strains by all related name:
fhuE b1102 ECK1088 JW1088
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General information (Go to Linear View: )
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Gene Name
|
fhuE
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Alternative name
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b1102,ECK1088,JW1088
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Location, Length
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1,158,585 - 1,160,774
(
-
)
;
24.97
min
;
2190
(bp) ,
729
(aa)
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Product
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ferric-rhodotorulic acid outer membrane transporter
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Operon Name
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fhuE
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Note
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outer membrane receptor for ferric iron uptake; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0009279 - cell outer membrane; GO_process: GO:0006826 - iron ion transport
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Function
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transport; Transport of small molecules: Cations
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Gene Ontology
|
GO:0004872
;
receptor activity ( fhuE )
GO:0005215
;
transporter activity ( fhuE )
GO:0005506
;
iron ion binding ( fhuE )
GO:0006810
;
transport ( fhuE )
GO:0006811
;
ion transport ( fhuE )
GO:0006826
;
iron ion transport ( fhuE )
GO:0009279
;
cell outer membrane ( fhuE )
GO:0015343
;
siderophore-iron transmembrane transporter activity ( fhuE )
GO:0015891
;
siderophore transport ( fhuE )
GO:0016020
;
membrane ( fhuE )
GO:0019867
;
outer membrane ( fhuE )
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PID
|
1787344
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EC number
(KEGG Pathway)
|
|
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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fhuE
(
EG10306
)
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Number of removed
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36 aa cleaved
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
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FHUE_ECOLI
(
P16869
;
P77292
)
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- Protein name
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FhuE receptor precursor (Outer-membrane receptor for Fe(III)-coprogen, Fe
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- Synonyms
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III)-ferrioxamine B and Fe(III)-rhodotrulic acid
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- Gene name
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Name=fhuE; OrderedLocusNames=b1102;
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- Comments
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FUNCTION:Required for the uptake of iron(III) via coprogen, ferrioxamine B, and rhodotorulic acid.
SUBCELLULAR LOCATION:Outer membrane.
INDUCTION:For induction, the tonB and the exbB proteins have to be active.
SIMILARITY:Belongs to the tonB-dependent receptor family.
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Entry name(Acc.no)
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Q8CW53
(
Q8CW53
)
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- Protein name
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FhuE receptor.
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- Synonyms
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- Gene name
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Name=fhuE; OrderedLocusNames=c1374;
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- Comments
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SUBCELLULAR LOCATION:Outer membrane (By similarity).
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Entry name(Acc.no)
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Q8X8H4
(
Q8X8H4
)
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- Protein name
|
Outer membrane receptor for ferric iron uptake.
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- Synonyms
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- Gene name
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Name=fhuE; OrderedLocusNames=z1741;
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- Comments
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SUBCELLULAR LOCATION:Outer membrane (By similarity).
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MMBR References
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Mol Gen Genet. 1983;191(2):301-6.
Identification of an iron uptake system specific for coprogen and rhodotorulic acid in Escherichia coli K12.
Hantke K.
(
6353165
)
|
J Bacteriol. 1987;169(5):2044-9.
Ferric-coprogen receptor FhuE of Escherichia coli: processing and sequence common to all TonB-dependent outer membrane receptor proteins.
Sauer M, Hantke K, Braun V.
(
3032906
)
|
Mol Microbiol. 1990;4(3):427-37.
Sequence of the fhuE outer-membrane receptor gene of Escherichia coli K12 and properties of mutants.
Sauer M, Hantke K, Braun V.
(
2162465
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MLSTQFNRDN QYQAITKPSL LAGCIALALL PSAAFAAPAT EETVIVEGSA TAPDDGENDY SVTSTSAGTK
0071 MQMTQRDIPQ SVTIVSQQRM EDQQLQTLGE VMENTLGISK SQADSDRALY YSRGFQIDNY MVDGIPTYFE
0141 SRWNLGDALS DMALFERVEV VRGATGLMTG TGNPSAAINM VRKHATSREF KGDVSAEYGS WNKERYVADL
0211 QSPLTEDGKI RARIVGGYQN NDSWLDRYNS EKTFFSGIVD ADLGDLTTLS AGYEYQRIDV NSPTWGGLPR
0281 WNTDGSSNSY DRARSTAPDW AYNDKEINKV FMTLKQQFAD TWQATLNATH SEVEFDSKMM YVDAYVNKAD
0351 GMLVGPYSNY GPGFDYVGGT GWNSGKRKVD ALDLFADGSY ELFGRQHNLM FGGSYSKQNN RYFSSWANIF
0421 PDEIGSFYNF NGNFPQTDWS PQSLAQDDTT HMKSLYAATR VTLADPLHLI LGARYTNWRV DTLTYSMEKN
0491 HTTPYAGLVF DINDNWSTYA SYTSIFQPQN DRDSSGKYLA PITGNNYELG LKSDWMNSRL TTTLAIFRIE
0561 QDNVAQSTGT PIPGSNGETA YKAVDGTVSK GVEFELNGAI TDNWQLTFGA TRYIAEDNEG NAVNPNLPRT
0631 TVKMFTSYRL PVMPELTVGG GVNWQNRVYT DTVTPYGTFR AEQGSYALVD LFTRYQVTKN FSLQGNVNNL
0701 FDKTYDTNVE GSIVYGTPRN FSITGTYQF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 catttgcatt tacaaacaaa attattcgca
-070 cactaaatat aatcgctcat caccctcctc cggcatgagc ctgacgacaa cataaaccaa gagatttcaa
0001 atgctttcaa cacaatttaa cagggataat caatatcaag ccatcaccaa accgtcacta cttgccggtt
0071 gcatagcact ggcactatta ccttctgccg cttttgctgc accagccact gaagaaacgg tgattgttga
0141 gggttcagcc acagctccag atgatggcga aaatgattac agcgtaacgt ctacctctgc gggtaccaaa
0211 atgcagatga ctcaacgtga tattcctcag tcggtcacta ttgttagcca gcagcggatg gaagatcagc
0281 agttacaaac gctgggcgaa gtgatggaaa acacgctggg gatcagcaaa agtcaggcgg attccgatcg
0351 tgctctttat tattcccgcg gattccagat cgataactat atggttgatg gtatccccac ctattttgaa
0421 tcgcgctgga atctgggcga cgcactttct gatatggcac tctttgaacg cgtagaagta gtgcgtggcg
0491 cgacaggact catgaccggg acgggtaatc catctgcggc aattaatatg gttcgaaaac acgcgaccag
0561 tcgtgaattt aaaggcgatg tctcggcgga atacggtagc tggaacaaag aacggtatgt ggcggattta
0631 caaagcccac tcaccgaaga cggtaaaatc cgcgcgcgaa ttgtcggcgg ctaccagaat aacgactcat
0701 ggctggaccg ctacaacagt gaaaagacct tcttctcggg cattgtcgat gctgatttag gcgatcttac
0771 gacgctttca gccggttacg aatatcagcg cattgatgtt aatagcccta cctggggcgg tttaccgcgc
0841 tggaatactg atggcagcag caacagttac gatcgcgcac gcagtaccgc acctgactgg gcgtacaacg
0911 ataaagagat caacaaggtc tttatgaccc tgaagcagca gtttgctgat acctggcaag cgacactgaa
0981 tgccacccac tctgaagtcg aatttgacag caaaatgatg tatgtcgatg cctatgtaaa caaagcggat
1051 ggtatgctgg ttgggccata cagtaattat ggacctggct ttgattatgt cggcggcacc ggttggaaca
1121 gtggcaaacg taaagttgat gcgctggatt tgttcgctga cggtagttat gaattgtttg gtcgtcagca
1191 caatctaatg tttggtggca gttacagcaa acaaaacaat cgttacttca gttcatgggc caacatcttc
1261 ccggatgaaa ttggcagttt ctacaacttt aatggcaatt tcccacaaac cgactggtca ccacagagcc
1331 tggcgcagga cgataccaca catatgaaat cgttatatgc tgccactcgt gtcacccttg ccgatccgct
1401 gcatctgatc ctcggcgcac gttataccaa ctggcgggtt gatacgctga cttacagcat ggagaaaaac
1471 cacaccacgc cttacgctgg tctggtgttt gacatcaatg acaactggtc gacctacgcc agctatacct
1541 ctattttcca gccgcaaaat gatcgtgaca gttcaggcaa atatctggct ccaatcaccg gtaacaacta
1611 cgagctgggt ctgaaatcgg actggatgaa tagccgtctg accaccacgt tagccatctt ccgtattgag
1681 caggataatg tcgctcagtc caccggtaca cctatccccg gcagcaacgg cgaaaccgcc tataaagcgg
1751 tggatgggac agtcagtaaa ggggtggaat ttgaactcaa cggcgcaatt accgacaact ggcagctgac
1821 atttggcgca acgcgctata ttgcagagga taacgaagga aacgccgtta atcctaatct gccacgcacc
1891 acggttaaaa tgttcaccag ctatcggttg cctgtcatgc cagagttgac ggtcggcggt ggtgttaact
1961 ggcaaaatcg cgtgtatacc gacaccgtga cgccgtatgg caccttccgc gccgagcaag gtagctacgc
2031 gctggtggat ctcttcaccc gctaccaggt gacgaaaaac ttctcgttac aggggaacgt caataacctg
2101 ttcgacaaaa cctacgatac caacgtggaa ggttctatcg tctacggcac accgcgtaat ttcagcatta
2171 ccggcacgta tcaattctga ataacacctg taaaaaaggc agccatctgg ctgccttagt ctccccaacg
2241 tcttacggat tagtggttac ggatgtactc atccatctcg gttttcaggt
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