PEC Original Annotations
|
Essentiality
|
Class
|
non-essential
|
References (PMID)
|
J Biol Chem. 1999;274(20):14006-11.
A mutated PtsG, the glucose transporter, allows uptake of D-ribose.
Oh H, Park Y, Park C.
(
10318813
)
|
|
Deletion
|
OCR01-1
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
rbsR
|
Related strains
|
Strains Search
|
Search strains by gene name:
rbsR
Search strains by all related name:
rbsR b3753 ECK3747 JW3732 o330
|
General information (Go to Linear View:)
|
Gene Name
|
rbsR
|
Alternative name
|
b3753,ECK3747,JW3732,o330
|
Location, Length
|
3,936,250 - 3,937,242
(
+
)
;
84.84
min
;
993
(bp) ,
330
(aa)
|
Product
|
DNA-binding transcriptional repressor of ribose metabolism
|
Operon Name
|
rbsDACBKR
|
Note
|
regulator for rbs operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006350 - transcription
|
Function
|
regulator; Degradation of small molecules: Carbon compounds
|
Gene Ontology
|
GO:0003677
;
DNA binding ( rbsR )
GO:0003700
;
transcription factor activity ( rbsR )
GO:0005515
;
protein binding ( rbsR )
GO:0005622
;
intracellular ( rbsR )
GO:0006350
;
transcription ( rbsR )
GO:0006355
;
regulation of transcription, DNA-dependent ( rbsR )
|
PID
|
1790194
|
EC number
(KEGG Pathway)
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
EcoGene
|
rbsR
(
EG10819
)
|
Number of removed
|
1 aa cleaved
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
RBSR_ECOLI
(
P25551
)
|
- Protein name
|
Ribose operon repressor.
|
- Synonyms
|
|
- Gene name
|
OrderedLocusNames=b3753, c4681, z5254, ECs4695, SF3836, S3931;
|
Homology Analysis
|
BLAST
|
Bacteria
|
GTOP
|
rbsR
(
homologous genes of other bacterias
)
|
PDB
(database updated :
2007.02.20
)
|
PSI-BLAST
|
Chain A, Purine Repressor-Hypoxanthine-Purf-Operator Complex
|
SWISS-PROT
(database updated :
2007.02.20
)
|
BLAST
|
Ribose operon repressor
|
PSI-BLAST
|
HTH-type transcriptional repressor purR (Purine nucleotide synthesis repressor)
|
nr
(database updated :
2007.02.20
)
|
BLAST
|
regulator for rbs operon [Escherichia coli UTI89]
|
Pfam 28.0
(database updated :
2015-05
)
|
Pfam
|
|
PROSITE
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
HTH_LACI_FAMILY
|
MMBR References
|
J Bacteriol. 1984;158(2):665-73.
D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport.
Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR.
(
6327616
)
|
Sequences |
Amino acid
FASTA format
|
0001 MATMKDVARL AGVSTSTVSH VINKDRFVSE AITAKVEAAI KELNYAPSAL ARSLKLNQTH TIGMLITAST
0071 NPFYSELVRG VERSCFERGY SLVLCNTEGD EQRMNRNLET LMQKRVDGLL LLCTETHQPS REIMQRYPTV
0141 PTVMMDWAPF DGDSDLIQDN SLLGGDLATQ YLIDKGHTRI ACITGPLDKT PARLRLEGYR AAMKRAGLNI
0211 PDGYEVTGDF EFNGGFDAMR QLLSHPLRPQ AVFTGNDAMA VGVYQALYQA ELQVPQDIAV IGYDDIELAS
0281 FMTPPLTTIH QPKDELGELA IDVLIHRITQ PTLQQQRLQL TPILMERGSA
|
Nucleotide
FASTA format
View sequence in neighbor 100bp
|
0001 ttggctacaa tgaaagatgt tgcccgcctg gcgggcgttt ctacctcaac agtttctcac gttatcaata
0071 aagatcgctt cgtcagtgaa gcgattaccg ccaaagttga agcggcgatt aaagaactca attacgcgcc
0141 atcagctctg gcgcgtagcc tcaaactcaa tcaaacacat accattggca tgttgatcac tgccagtacc
0211 aatcctttct attcagaact ggtgcgtggc gttgaacgca gctgcttcga acgcggttat agtctcgtcc
0281 tttgcaatac cgaaggcgat gaacagcgga tgaatcgcaa tctggaaacg ctgatgcaaa aacgcgttga
0351 tggcttgctg ttactgtgca ccgaaacgca tcaaccttcg cgtgaaatca tgcaacgtta tccgacagtg
0421 cctactgtga tgatggactg ggctccgttc gatggcgaca gcgatcttat tcaggataac tcgttgctgg
0491 gcggagactt agcaacgcaa tatctgatcg ataaaggtca tacccgtatc gcctgtatta ccggcccgct
0561 ggataaaact ccggcgcgcc tgcggttgga aggttatcgg gcggcgatga aacgtgcggg tctcaacatt
0631 cctgatggct atgaagtcac tggtgatttt gaatttaacg gcgggtttga cgctatgcgc caactgctat
0701 cacatccgct gcgtcctcag gccgtcttta ccggaaatga cgctatggct gttggcgttt accaggcgtt
0771 atatcaggca gagttacagg ttccgcagga tatcgcggtg attggctatg acgatatcga actggcaagc
0841 tttatgacgc caccattaac cactatccac caaccgaaag atgaactggg ggagctggcg attgatgtac
0911 tcatccatcg gataacccag ccgacccttc agcaacaacg attacaactt actccgattc tgatggaacg
0981 cggttcggct tag
|