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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR10
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
argH
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Related strains
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Strains Search
|
Search strains by gene name:
argH
Search strains by all related name:
argH b3960 ECK3951 JW3932
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General information (Go to Linear View: )
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Gene Name
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argH
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Alternative name
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b3960,ECK3951,JW3932
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Location, Length
|
4,154,873 - 4,156,246
(
+
)
;
89.55
min
;
1374
(bp) ,
457
(aa)
|
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Product
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argininosuccinate lyase
|
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Operon Name
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argCBH
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Note
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GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006526 - arginine biosynthetic process
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Function
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enzyme; Amino acid biosynthesis: Arginine
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Gene Ontology
|
GO:0003824
;
catalytic activity ( argH )
GO:0004056
;
argininosuccinate lyase activity ( argH )
GO:0005737
;
cytoplasm ( argH )
GO:0006526
;
arginine biosynthetic process ( argH )
GO:0008652
;
amino acid biosynthetic process ( argH )
GO:0016829
;
lyase activity ( argH )
GO:0042450
;
arginine biosynthetic process via ornithine ( argH )
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PID
|
1790398
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EC number
(KEGG Pathway)
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4.3.2.1
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
ARLY_ECOLI
(
P11447
;
Q47060
)
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- Protein name
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Argininosuccinate lyase
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- Synonyms
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EC 4.3.2.1, Arginosuccinase, ASAL
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- Gene name
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Name=argH; OrderedLocusNames=b3960;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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argH
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
|
Chain A, Crystal Structure Of S283a Duck Delta 2 Crystallin Mutant
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Argininosuccinate lyase
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PSI-BLAST
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Argininosuccinate lyase
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nr
(database updated :
2007.02.20
)
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BLAST
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argininosuccinate lyase [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMIDATION
ATP_GTP_A
FUMARATE_LYASES
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MMBR References
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J Bacteriol. 1992;174(11):3836-7.
Physical map location of the argFGH operon of Escherichia coli.
Hendrickson W, Rudd KE.
(
1592837
)
|
In K. D. MacDonald (ed.), Proceedings of the Second International Symposium on Genetics and Industrial Microorganisms. Academic Press, London, United Kingdom. 1976:369-389
Genetic control of arginine metabolism in prokaryotes.
Baumberg, S.
|
Gene. 1979;8(1):25-34.
Clustered arg genes on a BamHI segment of the Escherichia coli chromosome.
Moran MC, Mazaitis AJ, Vogel RH, Vogel HJ.
(
231541
)
|
Gene. 1979;5(3):207-31.
Cloning and endonuclease restriction analysis of argF and of the control region of the argECBH bipolar operon in Escherichia coli.
Crabeel M, Charlier D, Cunin R, Glansdorff N.
(
381103
)
|
| Sequences |
Amino acid
FASTA format
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0001 MALWGGRFTQ AADQRFKQFN DSLRFDYRLA EQDIVGSVAW SKALVTVGVL TAEEQAQLEE ALNVLLEDVR
0071 ARPQQILESD AEDIHSWVEG KLIDKVGQLG KKLHTGRSRN DQVATDLKLW CKDTVSELLT ANRQLQSALV
0141 ETAQNNQDAV MPGYTHLQRA QPVTFAHWCL AYVEMLARDE SRLQDALKRL DVSPLGCGAL AGTAYEIDRE
0211 QLAGWLGFAS ATRNSLDSVS DRDHVLELLS AAAIGMVHLS RFAEDLIFFN TGEAGFVELS DRVTSGSSLM
0281 PQKKNPDALE LIRGKCGRVQ GALTGMMMTL KGLPLAYNKD MQEDKEGLFD ALDTWLDCLH MAALVLDGIQ
0351 VKRPRCQEAA QQGYANATEL ADYLVAKGVP FREAHHIVGE AVVEAIRQGK PLEDLPLSEL QKFSQVIDED
0421 VYPILSLQSC LDKRAAKGGV SPQQVAQAIA FAQARLG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GTTTAACGGT ATGCCGATGG GTACGCGGAT
-070 TTTAGCTTAA GTTTTGTTGG CCGGAGGCGC AGCTTTCCGG CATTGAATTT CAAAATAAGG AAACAGAGTT
0001 atggcacttt ggggcgggcg ttttacccag gcagcagatc aacggttcaa acaattcaac gactcactgc
0071 gctttgatta ccgtctggcg gagcaggata ttgttggctc tgtggcctgg tccaaagccc tggtcacggt
0141 aggcgtgtta accgcagaag agcaggcgca actggaagag gcgctgaacg tgttgctgga agatgttcgc
0211 gccaggccac aacaaatcct tgaaagcgac gccgaagata tccatagctg ggtggaaggc aaactgatcg
0281 acaaagtggg ccagttaggc aaaaagctgc ataccgggcg tagccgtaat gatcaggtag cgactgacct
0351 gaaactgtgg tgcaaagata ccgttagcga gttactgacg gctaaccggc agctgcaatc ggcgctggtg
0421 gaaaccgcac aaaacaatca ggacgcggta atgccaggtt acactcacct gcaacgcgcc cagccggtga
0491 cgttcgcgca ctggtgcctg gcctatgttg agatgctggc gcgtgatgaa agccgtttgc aggatgcgct
0561 taagcgtctg gatgtcagcc cgctaggctg tggcgcgctg gcgggaacgg cctatgaaat cgaccgtgaa
0631 cagttagcag gctggctggg ctttgcttcg gcgacccgta acagtctcga cagcgtttct gaccgtgacc
0701 atgtgttgga actgctttct gctgccgcta tcggcatggt gcatctgtcg cgttttgctg aagatctgat
0771 tttctttaac accggcgaag cggggtttgt ggagctttct gaccgcgtga cttccggttc atcattaatg
0841 ccgcagaaga aaaacccgga tgcgctggag ctgattcgcg gtaaatgcgg ccgggtgcag ggggcgttaa
0911 ccggcatgat gatgacgctg aaaggtttgc cgctggctta caacaaagat atgcaggaag acaaagaagg
0981 tctgttcgac gcgctcgata cctggctgga ctgcctgcat atggcggcgc tggtgctgga cggcattcag
1051 gtgaaacgtc cacgttgcca ggaagcggct cagcagggtt acgccaacgc caccgaactg gcggattatc
1121 tggtggcgaa aggcgtaccg ttccgcgagg cgcaccatat tgttggtgaa gcggtggtgg aagccattcg
1191 tcagggcaaa ccgctggaag atctgccgct cagtgagttg cagaaattca gtcaggtgat tgacgaagat
1261 gtctatccga ttctgtcgct gcaatcgtgc ctcgacaagc gtgcggcaaa aggcggcgtc tcaccgcagc
1331 aggtggcgca ggcgattgct tttgcgcagg ctcggttagg gtaaGAACAT TTATATGTAT AAATTTGAGC
1401 CTGGCTTATC GCCGGGCTTT TTTATGGCAA AAAAAAGCGG ATCCTGGAGA TCCGCAAAAG TTCACGTTGG
1471 CTTT
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