|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
9-1
(LD)
,
DE(gpt-lac)5
,
DE(argF-lac)169
,
OCR36,37-6 (LD 9C::Ap)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
lacA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
lacA
Search strains by all related name:
lacA b0342 ECK0339 f203 JW0333
|
General information (Go to Linear View: )
|
|
Gene Name
|
lacA
|
|
Alternative name
|
b0342,ECK0339,f203,JW0333
|
|
Location, Length
|
360,473 - 361,084
(
-
)
;
7.77
min
;
612
(bp) ,
203
(aa)
|
|
Product
|
thiogalactoside acetyltransferase
|
|
Operon Name
|
lacZYA
|
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
|
enzyme; Degradation of small molecules: Carbon compounds
|
|
Gene Ontology
|
GO:0005737
;
cytoplasm ( lacA )
GO:0005989
;
lactose biosynthetic process ( lacA )
GO:0008415
;
acyltransferase activity ( lacA )
GO:0008870
;
galactoside O-acetyltransferase activity ( lacA )
GO:0016740
;
transferase activity ( lacA )
|
|
PID
|
1786537
|
EC number
(KEGG Pathway)
|
2.3.1.18
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
lacA
(
EG10524
)
|
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Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
THGA_ECOLI
(
P07464
;
P77862
)
|
|
- Protein name
|
Galactoside O-acetyltransferase
|
|
- Synonyms
|
EC 2.3.1.18, GAT, Thiogalactoside acetyltransferase
|
|
- Gene name
|
Name=lacA; OrderedLocusNames=b0342;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
lacA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Galactoside Acetyltransferase In Complex With Coenzyme A
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Galactoside O-acetyltransferase
|
|
PSI-BLAST
|
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
galactoside O-acetyltransferase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
HEXAPEP_TRANSFERASES
|
|
MMBR References
|
Proc Natl Acad Sci U S A. 1985;82:6414-6418
DNA sequence of the lactose operon: the lacA gene and the transcriptional termination region.
Hediger, M. A., D. F. Johnson, D. P. Nierlich, and I. Zabin.
|
Genetics 1963;48:157-169
The genetic basis of hypersynthesis of beta-galactoside.
Horiuchi, T., S. Horiuchi, and A. Novick.
|
| Sequences |
Amino acid
FASTA format
|
0001 MNMPMTERIR AGKLFTDMCE GLPEKRLRGK TLMYEFNHSH PSEVEKRESL IKEMFATVGE NAWVEPPVYF
0071 SYGSNIHIGR NFYANFNLTI VDDYTVTIGD NVLIAPNVTL SVTGHPVHHE LRKNGEMYSF PITIGNNVWI
0141 GSHVVINPGV TIGDNSVIGA GSIVTKDIPP NVVAAGVPCR VIREINDRDK HYYFKDYKVE SSV
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ccctgctgcg tcgtcaggtg aatgaagtcg
-070 cttaagcaat caatgtcgga tgcggcgcga gcgccttatc cgaccaacat atcataacgg agtgatcgca
0001 ttgaacatgc caatgaccga aagaataaga gcaggcaagc tatttaccga tatgtgcgaa ggcttaccgg
0071 aaaaaagact tcgtgggaaa acgttaatgt atgagtttaa tcactcgcat ccatcagaag ttgaaaaaag
0141 agaaagcctg attaaagaaa tgtttgccac ggtaggggaa aacgcctggg tagaaccgcc tgtctatttc
0211 tcttacggtt ccaacatcca tataggccgc aatttttatg caaatttcaa tttaaccatt gtcgatgact
0281 acacggtaac aatcggtgat aacgtactga ttgcacccaa cgttactctt tccgttacgg gacaccctgt
0351 acaccatgaa ttgagaaaaa acggcgagat gtactctttt ccgataacga ttggcaataa cgtctggatc
0421 ggaagtcatg tggttattaa tccaggcgtc accatcgggg ataattctgt tattggcgcg ggtagtatcg
0491 tcacaaaaga cattccacca aacgtcgtgg cggctggcgt tccttgtcgg gttattcgcg aaataaacga
0561 ccgggataag cactattatt tcaaagatta taaagttgaa tcgtcagttt aaattataaa aattgcctga
0631 tacgctgcgc ttatcaggcc tacaagttca gcgatctaca ttagccgcat ccggcatgaa caaagcgcag
0701 gaacaagcgt cg
|
