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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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LD3-18-1
(LD)
,
DE(relA-argA)216
,
OCL44,45-1
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
barA
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Related strains
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Strains Search
|
Search strains by gene name:
barA
Search strains by all related name:
barA airS b2786 ECK2780 gacC JW2757
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General information (Go to Linear View: )
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Gene Name
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barA
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Alternative name
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airS,b2786,ECK2780,gacC,JW2757
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Location, Length
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2,913,079 - 2,915,835
(
+
)
;
62.79
min
;
2757
(bp) ,
918
(aa)
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Product
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hybrid sensory histidine kinase, in two-component regulatory system with UvrY
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Operon Name
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barA
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Note
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sensor-regulator, activates OmpR by phophorylation; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006464 - protein modification process
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Function
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enzyme; Global regulatory functions
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Gene Ontology
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GO:0000155
;
two-component sensor activity ( barA )
GO:0000156
;
two-component response regulator activity ( barA )
GO:0000160
;
two-component signal transduction system (phosphorelay) ( barA )
GO:0004673
;
protein histidine kinase activity ( barA )
GO:0004871
;
signal transducer activity ( barA )
GO:0005524
;
ATP binding ( barA )
GO:0005886
;
plasma membrane ( barA )
GO:0006350
;
transcription ( barA )
GO:0006355
;
regulation of transcription, DNA-dependent ( barA )
GO:0007165
;
signal transduction ( barA )
GO:0016020
;
membrane ( barA )
GO:0016021
;
integral to membrane ( barA )
GO:0016301
;
kinase activity ( barA )
GO:0016310
;
phosphorylation ( barA )
GO:0016740
;
transferase activity ( barA )
GO:0016772
;
transferase activity, transferring phosphorus-containing groups ( barA )
GO:0018106
;
peptidyl-histidine phosphorylation ( barA )
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PID
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1789149
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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BARA_ECOLI
(
P26607
;
P77032
)
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- Protein name
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Sensor protein barA
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- Synonyms
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EC 2.7.3.-
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- Gene name
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Name=barA; OrderedLocusNames=b2786, c3349, z4101, ECs3646;
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MMBR References
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EMBO J. 1994;13:5195-5202
A novel device of bacterial signal transducers.
Ishige, K., S. Nagasawa, S. Tokishita, and T. Mizuno.
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Mol Microbiol. 1992;6(6):799-807.
A novel sensor-regulator protein that belongs to the homologous family of signal-transduction proteins involved in adaptive responses in Escherichia coli.
Nagasawa S, Tokishita S, Aiba H, Mizuno T.
(
1574005
)
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| Sequences |
Amino acid
FASTA format
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0001 MTNYSLRARM MILILAPTVL IGLLLSIFFV VHRYNDLQRQ LEDAGASIIE PLAVSTEYGM SLQNRESIGQ
0071 LISVLHRRHS DIVRAISVYD ENNRLFVTSN FHLDPSSMQL GSNVPFPRQL TVTRDGDIMI LRTPIISESY
0141 SPDESPSSDA KNSQNMLGYI ALELDLKSVR LQQYKEIFIS SVMMLFCIGI ALIFGWRLMR DVTGPIRNMV
0211 NTVDRIRRGQ LDSRVEGFML GELDMLKNGI NSMAMSLAAY HEEMQHNIDQ ATSDLRETLE QMEIQNVELD
0281 LAKKRAQEAA RIKSEFLANM SHELRTPLNG VIGFTRLTLK TELTPTQRDH LNTIERSANN LLAIINDVLD
0351 FSKLEAGKLI LESIPFPLRS TLDEVVTLLA HSSHDKGLEL TLNIKSDVPD NVIGDPLRLQ QIITNLVGNA
0421 IKFTENGNID ILVEKRALSN TKVQIEVQIR DTGIGIPERD QSRLFQAFRQ ADASISRRHG GTGLGLVITQ
0491 KLVNEMGGDI SFHSQPNRGS TFWFHINLDL NPNIIIEGPS TQCLAGKRLA YVEPNSAAAQ CTLDILSETP
0561 LEVVYSPTFS ALPPAHYDMM LLGIAVTFRE PLTMQHERLA KAVSMTDFLM LALPCHAQVN AEKLKQDGIG
0631 ACLLKPLTPT RLLPALTEFC HHKQNTLLPV TDESKLAMTV MAVDDNPANL KLIGALLEDM VQHVELCDSG
0701 HQAVERAKQM PFDLILMDIQ MPDMDGIRAC ELIHQLPHQQ QTPVIAVTAH AMAGQKEKLL GAGMSDYLAK
0771 PIEEERLHNL LLRYKPGSGI SSRVVTPEVN EIVVNPNATL DWQLALRQAA GKTDLARDML QMLLDFLPEV
0841 RNKVEEQLVG ENPEGLVDLI HKLHGSCGYS GVPRMKNLCQ LIEQQLRSGT KEEDLEPELL ELLDEMDNVA
0911 REASKILG
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TGACGCGTCG TCGTGCGTCG TTTTGCAGAG
-070 TAGAATTGCG CCATTGGCGA GACTTTCTCA ATTTAACAGT GTGACCTTAA TTGTCCCATA ACGGAACTCC
0001 atgaccaact acagcctgcg cgcacgcatg atgattctga tcctggcacc gaccgtcctt attggtttat
0071 tgctgagtat ctttttcgtc gtgcatcgct ataacgactt gcagcgtcaa ctggaagatg ccggtgccag
0141 cattattgag ccgcttgcag tttctactga atatggcatg agcctgcaaa atcgcgaatc tatcggtcag
0211 ttaataagcg tactgcatcg tcgccattcc gatattgttc gcgcgatttc ggtttatgat gaaaataacc
0281 gactctttgt cacctccaat tttcatcttg atccctcatc aatgcagctc ggcagcaacg tgccgtttcc
0351 tcgccagctc actgtcactc gtgacggcga tattatgatc ctccgcacgc cgattatttc tgagagttac
0421 tcccccgacg aatcgcccag tagcgatgcc aaaaatagtc aaaatatgtt gggatatatt gcgctggagc
0491 tggatcttaa atcggttcgc ttgcagcaat ataaagagat ctttatttcc agcgtgatga tgctgttttg
0561 tatcggtatt gcgcttattt ttggctggcg cttaatgcgc gatgtaaccg gtccgattcg caacatggtg
0631 aataccgtcg accgcatccg tcgcgggcaa ctcgacagcc gggtggaagg atttatgctc ggcgagctgg
0701 atatgctgaa aaacggtatc aactcgatgg caatgtcgct ggctgcttat cacgaagaga tgcagcacaa
0771 tatcgaccag gcgacgtccg atctgcgtga aacgctggag cagatggaaa ttcagaacgt tgagttagat
0841 ctggcgaaaa agcgcgccca ggaagcggcg cgtattaaat ccgagtttct ggcaaatatg tcacacgagc
0911 tgcgtacacc actgaatggt gttattggct ttacccgcct gacgctgaaa acagaattaa caccaacgca
0981 gcgcgatcac ctgaatacga ttgaacgttc ggcaaataat ttgctggcaa ttattaatga tgttctcgac
1051 ttctcgaaac tggaagcagg taagctgatt ctggaaagta ttccattccc actacgcagc acgctggatg
1121 aagtcgttac tctgctggca cattcttctc acgataaagg gttagaactg acgctcaata ttaaaagcga
1191 cgtgcctgat aacgtgatcg gcgacccgct gcgattacag caaatcatca ctaacctggt ggggaatgca
1261 attaaattca ccgagaatgg caacattgat attctggtag aaaaacgtgc gctgagtaat accaaagtgc
1331 agattgaagt gcagattcgg gataccggca ttggtattcc tgaacgcgat caatcgcgct tattccaggc
1401 cttccgacag gctgatgcca gtatttcccg ccgtcatggt ggcaccgggc tggggctggt gattacacaa
1471 aaactggtta atgaaatggg cggcgatatt tcgttccata gccagccgaa tcgcggttca actttctggt
1541 tccacattaa tctcgatctg aacccgaaca ttattatcga agggccatcc acccagtgcc tcgcaggtaa
1611 gcgcctggcc tatgtcgaac caaactccgc agcagcgcaa tgcacgctgg atattttaag tgaaacgccg
1681 ctggaagtgg tttatagccc aacgttctcc gcgctgcctc ccgcgcatta cgacatgatg ttgttaggca
1751 tcgcggtgac cttccgcgag ccgctaacaa tgcaacatga gcgattagcg aaagcggtat cgatgaccga
1821 tttcctgatg ctggcacttc cttgccatgc acaagtcaat gctgaaaaac tcaagcaaga tggtatcggc
1891 gcgtgtctgc tgaaaccatt aacacctaca cgcctgttgc ctgccctgac ggaattttgt catcacaaac
1961 aaaacacgct tttgcctgta accgatgaaa gtaagctggc aatgacagtc atggcggttg atgacaaccc
2031 cgctaacctg aaacttatcg gcgcattgct ggaagatatg gtgcaacatg tggaactttg cgatagcggg
2101 catcaggcgg ttgaacgggc gaaacagatg ccgttcgatt tgatcttaat ggatattcaa atgccggaca
2171 tggatggcat tcgggcctgc gaactcatcc accaactccc gcatcagcaa caaacgccgg ttatcgcggt
2241 aacggcgcat gcaatggccg ggcaaaaaga gaagctgctt ggcgcaggga tgagcgatta tctggcgaaa
2311 ccgattgaag aagagcgatt gcataatttg ttgttgcgct acaagcctgg cagcggtatt tcctctcgcg
2381 tcgtgacgcc cgaagtcaac gaaattgtgg tgaacccgaa tgcgaccctc gactggcaac tggcactacg
2451 ccaggcagca ggaaaaaccg atttagcgcg cgatatgctg caaatgttac tcgatttcct gcctgaagtt
2521 cgcaacaaag ttgaggaaca gctggttgga gaaaacccgg aaggcctggt tgatttgatt cataaactgc
2591 atggcagttg cggctatagc ggtgtgccac gtatgaagaa tctctgccaa ctgatcgaac aacagctacg
2661 tagcggtact aaagaagaag atttggaacc ggagctgctg gaactgttgg acgagatgga taatgtcgcg
2731 cgcgaagcca gcaaaattct cgggtaaTGG ATGTCTTGTC GAGTAGCAAT CGGCTTTTTA TGACGCTGGT
2801 TTCAGATTGG TGACAAAGTG CCTGTGTTTA TGCCGGATGC GGCGTTAACG CCTTATC
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