|
PEC Original Annotations
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|
Essentiality
|
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Class
|
non-essential
|
|
References (PMID)
|
J Bacteriol. 1978;136(3):839-43.
Isolation of Escherichia coli mutants with changed regulation of uracil uptake.
Fast R.
(
363695
)
|
|
|
Deletion
|
OCR19
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
argI
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
argI
Search strains by all related name:
argI b4254 ECK4247 JW4211
|
General information (Go to Linear View: )
|
|
Gene Name
|
argI
|
|
Alternative name
|
b4254,ECK4247,JW4211
|
|
Location, Length
|
4,475,330 - 4,476,334
(
-
)
;
96.46
min
;
1005
(bp) ,
334
(aa)
|
|
Product
|
ornithine carbamoyltransferase 1
|
|
Operon Name
|
argI
|
|
Note
|
GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006526 - arginine biosynthetic process
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Function
|
enzyme; Amino acid biosynthesis: Arginine
|
|
Gene Ontology
|
GO:0004585
;
ornithine carbamoyltransferase activity ( argI )
GO:0005737
;
cytoplasm ( argI )
GO:0006520
;
amino acid metabolic process ( argI )
GO:0006526
;
arginine biosynthetic process ( argI )
GO:0008652
;
amino acid biosynthetic process ( argI )
GO:0009348
;
ornithine carbamoyltransferase complex ( argI )
GO:0016597
;
amino acid binding ( argI )
GO:0016740
;
transferase activity ( argI )
GO:0016743
;
carboxyl- or carbamoyltransferase activity ( argI )
|
|
PID
|
1790703
|
EC number
(KEGG Pathway)
|
2.1.3.3
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
argI
(
EG10069
)
|
|
Number of removed
|
1 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
OTC1_ECOLI
(
P04391
)
|
|
- Protein name
|
Ornithine carbamoyltransferase chain I
|
|
- Synonyms
|
EC 2.1.3.3, OTCase-1
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- Gene name
|
Name=argI; OrderedLocusNames=b4254;
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Homology Analysis
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BLAST
|
|
Bacteria
|
|
GTOP
|
argI
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Ornithine Transcarbamylase From Escherichia Coli
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Ornithine carbamoyltransferase chain I
|
|
PSI-BLAST
|
Ornithine carbamoyltransferase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
ornithine carbamoyltransferase 1 [Escherichia coli K12]
|
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Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
AMIDATION
CARBAMOYLTRANSFERASE
|
|
MMBR References
|
Nucleic Acids Res. 1983;11:8509-8518
The DNA sequence of argI from Escherichia coli K12.
Bencini, D. A., J. E. Houghton, T. A. Hoover, K. F. Folterman, J. R. Wild, and G. A. O'Donovan.
|
EMBO J. 1982;1(7):853-7.
Homologous control sites and DNA transcription starts in the related argF and argI genes of Escherichia coli K12.
Piette J, Cunin R, Van Vliet F, Charlier D, Crabeel M, Ota Y, Glansdorff N.
(
6329710
)
|
Mol Gen Genet. 1982;187(3):391-400.
The organization and regulation of the pyrBI operon in E. coli includes a rho-independent attenuator sequence.
Roof WD, Foltermann KF, Wild JR.
(
6294470
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MSGFYHKHFL KLLDFTPAEL NSLLQLAAKL KADKKSGKEE AKLTGKNIAL IFEKDSTRTR CSFEVAAYDQ
0071 GARVTYLGPS GSQIGHKESI KDTARVLGRM YDGIQYRGYG QEIVETLAEY ASVPVWNGLT NEFHPTQLLA
0141 DLLTMQEHLP GKAFNEMTLV YAGDARNNMG NSMLEAAALT GLDLRLVAPQ ACWPEAALVT ECRALAQQNG
0211 GNITLTEDVA KGVEGADFIY TDVWVSMGEA KEKWAERIAL LREYQVNSKM MQLTGNPEVK FLHCLPAFHD
0281 DQTTLGKKMA EEFGLHGGME VTDEVFESAA SIVFDQAENR MHTIKAVMVA TLSK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cacctttgtg acaaagattt atgctttaga
-070 cttgcaaatg aataatcatc catataaatt gaattttaat tcattgaggc gttagccaca ggagggatct
0001 atgtccgggt tttatcataa gcatttcctg aaattactcg atttcacgcc agctgaactc aacagcctgc
0071 tgcagttagc cgcgaagctg aaagccgata agaaaagcgg taaagaagaa gccaaactca ctggtaaaaa
0141 catcgcgctc atcttcgaaa aagactcgac tcgtacccga tgctctttcg aagttgccgc atatgaccag
0211 ggtgctcgcg ttacttatct cggcccaagc ggcagccaga ttggtcataa agagtcgatt aaagacactg
0281 cccgcgtgct tggtcgcatg tatgacggta ttcagtatcg cggctatggt caggagattg tcgaaacact
0351 ggcggaatac gctagcgtgc cggtatggaa tggcctgacc aatgagttcc atcccacgca gctgctggcg
0421 gatcttctca ccatgcagga gcatttgccc ggcaaagcgt tcaacgaaat gacgctggtc tatgcaggtg
0491 acgcgcgtaa caacatgggc aattcgatgc tcgaagctgc ggcgcttacc ggtctggatt tgcgtctggt
0561 cgcgccacaa gcgtgctggc cggaagctgc gctggttacg gaatgccgcg ccctggcaca gcaaaatggt
0631 gggaatatta cgctgactga agatgtcgcg aagggagttg aaggtgctga ctttatctat accgatgtgt
0701 gggtgtcgat gggggaagca aaagagaaat gggcggaacg gattgcattg ctgcgtgaat atcaggtgaa
0771 cagcaagatg atgcagttga ccggtaaccc ggaggtcaaa ttcctccact gcctgcccgc gtttcatgac
0841 gaccaaacga cgcttggcaa gaaaatggcg gaagaatttg gcctacatgg cggtatggaa gtcactgatg
0911 aggtcttcga atctgccgcc agcattgttt ttgatcaggc ggaaaaccgt atgcatacta tcaaagcggt
0981 gatggtcgcg acgctcagta aataattgct atcgctataa agatgccggg aaatacaaac catcccggca
1051 tcacattatt ttatgcagtg ataggtctat tcttccaccc aaagtgttct attgc
|
