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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
OCR26
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
deoB
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Related strains
|
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Strains Search
|
Search strains by gene name:
deoB
Search strains by all related name:
deoB b4383 drm ECK4375 JW4346 thyR tlr trl
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General information (Go to Linear View: )
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Gene Name
|
deoB
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Alternative name
|
b4383,drm,ECK4375,JW4346,thyR,tlr,trl
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Location, Length
|
4,617,626 - 4,618,849
(
+
)
;
99.52
min
;
1224
(bp) ,
407
(aa)
|
|
Product
|
phosphopentomutase
|
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Operon Name
|
deoCABD
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Note
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GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion
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Function
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enzyme; Salvage of nucleosides and nucleotides
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Gene Ontology
|
GO:0000287
;
magnesium ion binding ( deoB )
GO:0003824
;
catalytic activity ( deoB )
GO:0005737
;
cytoplasm ( deoB )
GO:0008973
;
phosphopentomutase activity ( deoB )
GO:0009117
;
nucleotide metabolic process ( deoB )
GO:0009166
;
nucleotide catabolic process ( deoB )
GO:0009264
;
deoxyribonucleotide catabolic process ( deoB )
GO:0016853
;
isomerase activity ( deoB )
GO:0030145
;
manganese ion binding ( deoB )
GO:0043094
;
metabolic compound salvage ( deoB )
GO:0046872
;
metal ion binding ( deoB )
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|
PID
|
1790843
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EC number
(KEGG Pathway)
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5.4.2.7
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
DEOC_ECOLI
(
P00882
)
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- Protein name
|
Deoxyribose-phosphate aldolase
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- Synonyms
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EC 4.1.2.4, Phosphodeoxyriboaldolase, Deoxyriboaldolase, DERA
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- Gene name
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Name=deoC; Synonyms=dra, thyR; OrderedLocusNames=b4381, c5465;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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deoB
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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Chain A, Crystal Structure Of Putative Phosphopentomutase From Streptococcus Mutans
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Phosphopentomutase (Phosphodeoxyribomutase)
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PSI-BLAST
|
Phosphopentomutase (Phosphodeoxyribomutase)
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nr
(database updated :
2007.02.20
)
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BLAST
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phosphopentomutase [Escherichia coli O157:H7 EDL933]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMIDATION
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MMBR References
|
Gene. 1982;17(3):291-8.
The cloning of the Escherichia coli K-12 deoxyribonucleoside operon.
Fischer M, Short SA.
(
6286410
)
|
Mol Gen Genet. 1969;104(4):351-9.
A map of four genes specifying enzymes involved in catabolism of nucleosides and deoxynucleosides in Escherichia coli.
Ahmad SI, Pritchard RH.
(
4904508
)
|
J Bacteriol. 1968;96(2):501-14.
Characteristics of the deo operon: role in thymine utilization and sensitivity to deoxyribonucleosides.
Lomax MS, Greenberg GR.
(
4877128
)
|
Mol Gen Genet. 1979;176(3):361-8.
Cloning the trpR gene.
Roeder W, Somerville RL.
(
160491
)
|
Eur J Biochem. 1982;125:561-566
The primary structure of Escherichia coli K12 2-deoxyribose 5-phosphate aldolase. Nucleotide sequence of the deoC gene and the amino acid sequence of the enzyme.
Valentin-Hansen, P., F. Boetius, K. Hammer-Jespersen, and I. Svendsen.
|
Nucleic Acids Res. 1984;12:5211-5224
The internal regulated promoter of the deo operon of Escherichia coli K-12.
Valentin-Hansen, P., K. Hammer, E. L. Larsen, and I. Svendsen.
|
J Mol Biol. 1979;133(1):1-17.
Evidence for the existence of three promoters for the deo operon of Escherichia coli K12 in vitro.
Valentin-Hansen P, Hammer-Jespersen K, Buxton RS.
(
231107
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKRAFIMVLD SFGIGATEDA ERFGDVGADT LGHIAEACAK GEADNGRKGP LNLPNLTRLG LAKAHEGSTG
0071 FIPAGMDGNA EVIGAYAWAH EMSSGKDTPS GHWEIAGVPV LFEWGYFSDH ENSFPQELLD KLVERANLPG
0141 YLGNCHSSGT VILDQLGEEH MKTGKPIFYT SADSVFQIAC HEETFGLDKL YELCEIAREE LTNGGYNIGR
0211 VIARPFIGDK AGNFQRTGNR HDLAVEPPAP TVLQKLVDEK HGQVVSVGKI ADIYANCGIT KKVKATGLDA
0281 LFDATIKEMK EAGDNTIVFT NFVDFDSSWG HRRDVAGYAA GLELFDRRLP ELMSLLRDDD ILILTADHGC
0351 DPTWTGTDHT REHIPVLVYG PKVKPGSLGH RETFADIGQT LAKYFGTSDM EYGKAMF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TAAAGCACCG GAAAGCACAC CAACTGTCTA
-070 TCGCCGTATC AGCGAATAAC GGTATACTGA TCTGATCATT TAAATTTGAA GCACTGAGTA CGGAGAACAT
0001 atgaaacgtg catttattat ggtgctggac tcattcggca tcggcgctac agaagatgca gaacgctttg
0071 gtgacgtcgg ggctgacacc ctgggtcata tcgcagaagc ttgtgccaaa ggcgaagctg ataacggtcg
0141 taaaggcccg ctcaatctgc caaatctgac ccgtctgggg ctggcgaaag cacacgaagg ttctaccggt
0211 ttcattccgg cgggaatgga cggcaacgct gaagttatcg gcgcgtacgc atgggcgcac gaaatgtcat
0281 ccggtaaaga taccccgtct ggtcactggg aaattgccgg tgtcccggtt ctgtttgagt ggggatattt
0351 ctccgatcac gaaaacagct tcccgcaaga gctgctggat aaactggtcg aacgcgctaa tctgccgggt
0421 tacctcggta actgccactc ttccggtacg gtcattctgg atcaactggg cgaagagcac atgaaaaccg
0491 gcaagccgat tttctatacc tccgctgact ccgtgttcca gattgcctgc catgaagaaa ctttcggtct
0561 ggataaactc tacgaactgt gcgaaatcgc ccgtgaagag ctgaccaacg gcggctacaa tatcggtcgt
0631 gttatcgctc gtccgtttat cggcgacaaa gccggtaact tccagcgtac cggtaaccgt cacgacctgg
0701 ctgttgagcc gccagcaccg accgtgctgc agaaactggt tgatgaaaaa cacggccagg tggtttctgt
0771 cggtaaaatt gcggacatct acgccaactg cggtatcacc aaaaaagtga aagcgactgg cctggacgcg
0841 ctgtttgacg ccaccatcaa agagatgaaa gaagcgggtg ataacaccat cgtcttcacc aacttcgttg
0911 acttcgactc ttcctggggc caccgtcgcg acgtcgccgg ttatgccgcg ggtctggaac tgttcgaccg
0981 ccgtctgccg gagctgatgt ctctgctgcg cgatgacgac atcctgatcc tcaccgctga ccacggttgc
1051 gatccgacct ggaccggtac tgaccacacg cgtgaacaca ttccggtact ggtatatggc ccgaaagtaa
1121 aaccgggctc actgggtcat cgtgaaacct tcgcggatat cggccagact ctggcaaaat attttggtac
1191 ttctgatatg gaatatggca aagccatgtt ctgaTGGATT TGGGCGGAGC GTTGACTCCG CCTTTGTTAT
1261 GTCACAAAAA GGATAAAACA ATGGCTACCC CACACATTAA TGCAGAAATG GGCGATTTCG CTGA
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