Mutants (Isolated)

tm935

Allele Name

tm935

Sequence Name

F29G9.3

CGC Name

aps-1

Worm Base

Allele Name

tm935

CGC Name

aps-1

Sequence

F29G9.3

Phenotype

lethal or sterile. Dr. G. Hermann: WT gut granules. Dr. S. L'Hernault: could not recover. Dr. O. Blacque: could not assess Dyf. Dr. G. Michaux: L1 Lvl.

Mutation site

17718/17719-TCAT-18023/18024 (305 bp deletion + 4 bp insertion)

Chromosome

Putative gene structure

join(17476..17553, 17602..17705, 17960..18251)

Map position

-0.42

Balancer

nT1 [qIs51]

Map position of balancer

Sequence of primers

IntRev:CGTCTCGGAGTTGTGATAAT,ExtRev:CCCCTGTTCGTGTTTTACAC,IntFwd:CGTAGTATTCAGGATGAGTC,ExtFwd:CAGTACCAGGACAACCGTAT

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Zhang H, Kim A, Abraham N, Khan LA, Hall DH, Fleming JT, Gobel V.
Clathrin and AP-1 regulate apical polarity and lumen formation during C. elegans tubulogenesis.
Development 2012 139(11) 2071-83
[ PubMed ID = 22535410 ] [ RRC reference ]

Shafaq-Zadah M, Brocard L, Solari F, Michaux G.
AP-1 is required for the maintenance of apico-basal polarity in the C. elegans intestine.
Development 2012 139(11) 2061-70
[ PubMed ID = 22535414 ] [ RRC reference ]

Hermann GJ, Schroeder LK, Hieb CA, Kershner AM, Rabbitts BM, Fonarev P, Grant BD, Priess JR.
Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.
Mol Biol Cell 2005 16(7) 3273-88
[ PubMed ID = 15843430 ] [ RRC reference ]