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Mutants (Isolated)

Allele Name		tm935
Sequence Name		F29G9.3
CGC Name		aps-1
Worm Base	Allele Name	tm935
	CGC Name	aps-1
	Sequence	F29G9.3
Phenotype		lethal or sterile. Dr. G. Hermann: WT gut granules. Dr. S. L'Hernault: could not recover. Dr. O. Blacque: could not assess Dyf. Dr. G. Michaux: L1 Lvl.
Mutation site		17718/17719-TCAT-18023/18024 (305 bp deletion + 4 bp insertion)
Chromosome		V
Putative gene structure		join(17476..17553, 17602..17705, 17960..18251)
Map position		-0.42
Balancer		nT1 [qIs51]
Map position of balancer
Sequence of primers		IntRev:CGTCTCGGAGTTGTGATAAT,ExtRev:CCCCTGTTCGTGTTTTACAC,IntFwd:CGTAGTATTCAGGATGAGTC,ExtFwd:CAGTACCAGGACAACCGTAT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Shafaq-Zadah M, Brocard L, Solari F, Michaux G. AP-1 is required for the maintenance of apico-basal polarity in the C. elegans intestine. Development 2012 139(11) 2061-70  [ PubMed ID = 22535414 ] [ RRC reference ] Zhang H, Kim A, Abraham N, Khan LA, Hall DH, Fleming JT, Gobel V. Clathrin and AP-1 regulate apical polarity and lumen formation during C. elegans tubulogenesis. Development 2012 139(11) 2071-83  [ PubMed ID = 22535410 ] [ RRC reference ] Hermann GJ, Schroeder LK, Hieb CA, Kershner AM, Rabbitts BM, Fonarev P, Grant BD, Priess JR. Genetic analysis of lysosomal trafficking in Caenorhabditis elegans. Mol. Biol. Cell 2005 16(7) 3273-88  [ PubMed ID = 15843430 ] [ RRC reference ]