Mutants (Isolated)

tm797

Allele Nametm797
Allele TypeNormal
Sequence NameF11D5.3
Gene NameF11D5.3
Worm BaseAllele Name tm797
Gene Name F11D5.3
Sequence F11D5.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. T. Schedl: fertile, normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 19813/19814-20162/20163 (349 bp deletion)
ChromosomeX
Putative gene structurejoin(13790..13856, 16299..16404, 17621..17718, 17768..17901, 19471..19618, 19728..20017, 20062..20374, 20428..20695, 20915..20986, 21035..21261, 21311..21440, 21488..21565, 21894..22200, 22251..22406)
Map position-10.56
Balancer
Map position of balancer
Sequence of primersIntFwd:CGACATCTTGACCGGGCAAT,ExtFwd:GCTAATAATGACACGGAGCA,IntRev:CTTTCGAGCTACAGGTAAAG,ExtRev:GGAGCACTGGGAGTCTAGGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Park K, Jayadev R, Payne SG, Kenny-Ganzert IW, Chi Q, Costa DS, Ramos-Lewis W, Thendral SB, Sherwood DR.
Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues.
Elife 2023 12  
[ PubMed ID = 37405383 ] [ RRC reference ]

Shimizu T, Kato Y, Sakai Y, Hisamoto N, Matsumoto K.
N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans.
Genetics 2019 213(2) 491-500 
[ PubMed ID = 31371405 ] [ RRC reference ]

Hisamoto N, Nagamori Y, Shimizu T, Pastuhov SI, Matsumoto K.
The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon Regeneration.
PLoS Genet 2016 12(12) e1006475 
[ PubMed ID = 27984580 ] [ RRC reference ]

Unsoeld T, Park JO, Hutter H.
Discoidin domain receptors guide axons along longitudinal tracts in C. elegans.
Dev Biol 2013 374(1) 142-52 
[ PubMed ID = 23147028 ] [ RRC reference ]