Mutants (Isolated)

tm796

Allele Nametm796
Sequence NameT17E9.2a
CGC Namenmt-1
Worm BaseAllele Name tm796
CGC Name nmt-1
Sequence T17E9.2a
Phenotypehomozygous viable. Dr. M. Nonet: sterile, animals grow up normally. most are sterile and a few lay a few progeny. granddaughters are completely sterile.
Mutation site7324/7325-7817/7819 (493 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(6015..6341, 6395..7188, 7269..7401, 7450..7548))
Map position-1.42
Balancer
Map position of balancer
Sequence of primersExtRev:AATGTTGCGCAGAGAACTGA,ExtFwd:CTTGGCTTCATGTCGGCGCA,IntRev:CTGAAAACGCCAGTTGACAT,IntFwd:GCGCACTTCCAGTTGTACAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Galvin BD, Li Z, Villemaine E, Poole CB, Chapman MS, Pollastri MP, Wyatt PG, Carlow CK.
A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes.
PLoS Negl Trop Dis 2014 8(9) e3145 
[ PubMed ID = 25188325 ] [ RRC reference ]

C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]