Mutants (Isolated)

tm775

Allele Nametm775
Sequence NameC16C2.2
CGC Nameeat-16
Worm BaseAllele Name tm775
CGC Name eat-16
Sequence C16C2.2
Phenotypelethal or sterile. Dr. E. Jorgensen: pale, thin and hyperactive.
Mutation site10403/10404-11357/11358 (954 bp deletion)
ChromosomeI
Putative gene structurejoin(9906..9926, 9977..10096, 10207..10290, 10355..10448, 10493..10571, 10949..11245, 11383..11496, 11544..12054, 12101..12186, 12504..12519)
Map position3.87
BalancerhT2 [qIs48]
Map position of balancer
Sequence of primersIntFwd:CAGCAATTGATAGCTCTCGT,ExtFwd:CCTCATGCCATCACCGGTCA,ExtRev:ACTTGACCCCATGAGCCTGT,IntRev:TGGCAGCGAGTCGGACGATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hoyt JM, Wilson SK, Kasa M, Rise JS, Topalidou I, Ailion M.
The SEK-1 p38 MAP Kinase Pathway Modulates Gq Signaling in Caenorhabditis elegans.
G3 (Bethesda) 2017 7(9) 2979-2989 
[ PubMed ID = 28696924 ] [ RRC reference ]

Topalidou I, Cooper K, Pereira L, Ailion M.
Dopamine negatively modulates the NCA ion channels in C. elegans.
PLoS Genet. 2017 13(10) e1007032 
[ PubMed ID = 28968387 ] [ RRC reference ]