Mutants (Isolated)

tm6801

Allele Nametm6801
Allele TypeNormal
Sequence NameC15C8.3
Gene Nameasp-10
Worm BaseAllele Name tm6801
Gene Name asp-10
Sequence C15C8.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 9732/9733-C-9971/9972(239bp deletion + 1 bp insertion)
ChromosomeV
Putative gene structurejoin(9115..9185, 9228..9507, 9555..9631, 9677..9812, 9931..10262, 10314..10427, 10876..11152)
Map position4.62
Balancer
Map position of balancer
Sequence of primersExtRev:GCAAGGCCAAGTCTTCCGCT,IntFwd:GCCAGTCTAAGCATCGGTTC,IntRev:CATGTACGTGGCAATAGGCA,ExtFwd:GAACCACTGACGCTTGCCAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Gaeta AL, Willicott K, Willicott CW, McKay LE, Keogh CM, Altman TJ, Kimble LC, Yarbrough AL, Caldwell KA, Caldwell GA.
Mechanistic impacts of bacterial diet on dopaminergic neurodegeneration in a Caenorhabditis elegans α-synuclein model of Parkinson's disease.
iScience 2023 26(6) 106859 
[ PubMed ID = 37260751 ] [ RRC reference ]

Min H, Lee YU, Shim YH, Kawasaki I.
Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans.
PLoS Genet 2019 15(5) e1008150 
[ PubMed ID = 31125345 ] [ RRC reference ]

Sinclair J, Pinter K, Samuel T, Beardsley S, Yuan X, Zhang J, Meng K, Yun S, Krause M, Hamza I.
Inter-organ signalling by HRG-7 promotes systemic haem homeostasis.
Nat Cell Biol 2017 19(7) 799-807 
[ PubMed ID = 28581477 ] [ RRC reference ]