Mutants (Isolated)

tm6234

Allele Nametm6234
Sequence NameF35D2.5
CGC Namesyd-1
Worm BaseAllele Name tm6234
CGC Name syd-1
Sequence F35D2.5
Phenotypehomozygous viable.
Mutation site24635/24636-25899/25900 (1264 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(22580..22662, 23204..23354, 23402..23757, 23825..24260, 24314..24792, 25087..25209, 25258..25525, 25677..25794, 25910..26064, 27634..27735, 27781..27859, 27902..28027, 28077..28226, 28271..28385, 28482..28524, 31067..31170, 31333..31408))
Map position0.5
Balancer
Map position of balancer
Sequence of primersExtFwd:GCCCACGTCCTTCGACAATG,IntFwd:AACTGCTCACGCTTAAGCGA,ExtRev:CAGGGACCTTAGCAGCCGTT,IntRev:GTGCCCAAAACGACGCCGTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Edwards SL, Yorks RM, Morrison LM, Hoover CM, Miller KG.
Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans.
Genetics 2015 201(1) 91-116 
[ PubMed ID = 26354975 ] [ RRC reference ]

Edwards SL, Morrison LM, Yorks RM, Hoover CM, Boominathan S, Miller KG.
UNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons.
Genetics 2015 201(1) 117-41 
[ PubMed ID = 26354976 ] [ RRC reference ]

Xu Y, Taru H, Jin Y, Quinn CC.
SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase.
PLoS Genet. 2015 11(4) e1005185 
[ PubMed ID = 25876065 ] [ RRC reference ]