Mutants (Isolated)

tm6234

Allele Nametm6234
Allele TypeNormal
Sequence NameF35D2.5
Gene Namesyd-1
Worm BaseAllele Name tm6234
Gene Name syd-1
Sequence F35D2.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 24635/24636-25899/25900 (1264 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(22580..22662, 23204..23354, 23402..23757, 23825..24260, 24314..24792, 25087..25209, 25258..25525, 25677..25794, 25910..26064, 27634..27735, 27781..27859, 27902..28027, 28077..28226, 28271..28385, 28482..28524, 31067..31170, 31333..31408))
Map position0.5
Balancer
Map position of balancer
Sequence of primersExtFwd:GCCCACGTCCTTCGACAATG,IntFwd:AACTGCTCACGCTTAAGCGA,ExtRev:CAGGGACCTTAGCAGCCGTT,IntRev:GTGCCCAAAACGACGCCGTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Nørgaard S, Deng S, Cao W, Pocock R.
Distinct CED-10/Rac1 domains confer context-specific functions in development.
PLoS Genet 2018 14(9) e1007670 
[ PubMed ID = 30265669 ] [ RRC reference ]

Xu Y, Taru H, Jin Y, Quinn CC.
SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase.
PLoS Genet 2015 11(4) e1005185 
[ PubMed ID = 25876065 ] [ RRC reference ]

Edwards SL, Yorks RM, Morrison LM, Hoover CM, Miller KG.
Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans.
Genetics 2015 201(1) 91-116 
[ PubMed ID = 26354975 ] [ RRC reference ]

Edwards SL, Morrison LM, Yorks RM, Hoover CM, Boominathan S, Miller KG.
UNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons.
Genetics 2015 201(1) 117-41 
[ PubMed ID = 26354976 ] [ RRC reference ]