Mutants (Isolated)

tm5210

Allele Nametm5210
Allele TypeBalanced
Sequence NameF52C9.1
Gene NameF52C9.1
Worm BaseAllele Name tm5210
Gene Name F52C9.1
Sequence F52C9.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26089/26090-CA-27278/27279 (1189 bp deletion + 2 bp insertion)
ChromosomeIII
Putative gene structurejoin(24821..24996, 25411..26136, 26408..26625, 26715..26863, 26964..27137, 27189..27269, 27487..27624, 27671..28004, 28049..28551, 28718..29068, 29289..29447, 29718..30067, 30124..30246, 30292..30653, 30777..30883, 31370..31539, 31586..31733)
Map position-1.83
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:ATCCCGCTCCACTGAACTAA,IntFwd:TCAACACCTCATTCGACCCT,ExtRev:CGCAAGAGATGATCGTGATC,IntRev:GAACGGATCGGATCATGTAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Liu X, Yin L, Li T, Lin L, Zhang J, Li Y.
Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
PLoS Genet 2021 17(3) e1009415 
[ PubMed ID = 33730050 ] [ RRC reference ]

Liu K, Jian Y, Sun X, Yang C, Gao Z, Zhang Z, Liu X, Li Y, Xu J, Jing Y, Mitani S, He S, Yang C.
Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
J Cell Biol 2016 212(2) 181-98 
[ PubMed ID = 26783301 ] [ RRC reference ]