Mutants (Isolated)

tm5040

Allele Name

tm5040

Sequence Name

T27F6.4

CGC Name

T27F6.4

Worm Base

Allele Name

CGC Name

Sequence

Phenotype

homozygous viable.

Mutation site

13777/13778-AAAATATAAAATATAT-14506/14507 (729 bp deletion + 16 bp insertion)

Chromosome

Putative gene structure

join(14022..14204, 14852..15130, 15804..15962)

Map position

13.23

Balancer

Map position of balancer

Sequence of primers

IntFwd:CACGCTTTTGCCGTGGGAAT,ExtRev:AAGGGCTTGGGACTGCGAAA,IntRev:GGACTGCGAAAATCAGGCTT,ExtFwd:AGCGCACAGTTTCCCACGCT

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Brenner JL, Schedl T.
Germline Stem Cell Differentiation Entails Regional Control of Cell Fate Regulator GLD-1 in Caenorhabditis elegans.
Genetics 2016 202(3) 1085-103
[ PubMed ID = 26757772 ] [ RRC reference ]

Shin H, Haupt KA, Kershner AM, Kroll-Conner P, Wickens M, Kimble J.
SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans.
PLoS Genet 2017 13(12) e1007121
[ PubMed ID = 29232700 ] [ RRC reference ]

Kershner AM, Shin H, Hansen TJ, Kimble J.
Discovery of two GLP-1/Notch target genes that account for the role of GLP-1/Notch signaling in stem cell maintenance.
Proc Natl Acad Sci U S A 2014 111(10) 3739-44
[ PubMed ID = 24567412 ] [ RRC reference ]