Mutants (Isolated)


Allele Nametm458
Sequence NameF31A3.2
CGC Namehlh-28
Worm BaseAllele Name tm458
CGC Name hlh-28
Sequence F31A3.2
Phenotypehomozygous viable. Dr. R. Lin, Dr. M. Maduro: normal cell division during 8-30 cell stage. Dr. P. Sengupta: normal dye-filling into sensory neurons. Dr. J. Priess: Dev. Cell 8, 867-879 (2005). Dr. C.M. Johnson: BBA 1769, 5 (2007).
Mutation site19745/19746-21019/21020 (1274 bp deletion)
Putative gene structurejoin(18012..18080, 19345..19514, 19567..19791, 19841..20165)
Map position24.35
Map position of balancer
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Lanjuin A, Claggett J, Shibuya M, Hunter CP, Sengupta P.
Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1.
Dev. Biol. 2006 290(1) 139-51 
[ PubMed ID = 16376329 ] [ RRC reference ]

McMiller TL, Sims D, Lee T, Williams T, Johnson CM.
Molecular characterization of the Caenorhabditis elegans REF-1 family member, hlh-29/hlh-28.
Biochim. Biophys. Acta 2007 1769(1) 5-19 
[ PubMed ID = 17258327 ] [ RRC reference ]

Neves A, Priess JR.
The REF-1 family of bHLH transcription factors pattern C. elegans embryos through Notch-dependent and Notch-independent pathways.
Dev. Cell 2005 8(6) 867-79 
[ PubMed ID = 15935776 ] [ RRC reference ]