Mutants (Isolated)


Allele Nametm4477
Sequence NameC02F5.6
CGC Namehenn-1
Worm BaseAllele Name tm4477
CGC Name henn-1
Sequence C02F5.6
Phenotypehomozygous viable.
Mutation site7132/7133-7505/7506 (373 bp deletion)
Putative gene structurejoin(6193..6234, 6422..6873, 6928..7086, 7137..7491, 7539..7652, 7726..7863)
Map position-0.36
Map position of balancer
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Alberti C, Manzenreither RA, Sowemimo I, Burkard TR, Wang J, Mahofsky K, Ameres SL, Cochella L.
Cell-type specific sequencing of microRNAs from complex animal tissues.
Nat Methods 2018 15(4) 283-289 
[ PubMed ID = 29481550 ] [ RRC reference ]

Billi AC, Freeberg MA, Day AM, Chun SY, Khivansara V, Kim JK.
A conserved upstream motif orchestrates autonomous, germline-enriched expression of Caenorhabditis elegans piRNAs.
PLoS Genet 2013 9(3) e1003392 
[ PubMed ID = 23516384 ] [ RRC reference ]

Billi AC, Alessi AF, Khivansara V, Han T, Freeberg M, Mitani S, Kim JK.
The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs.
PLoS Genet 2012 8(4) e1002617 
[ PubMed ID = 22548001 ] [ RRC reference ]

Tang W, Tu S, Lee HC, Weng Z, Mello CC.
The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans.
Cell 2016 164(5) 974-84 
[ PubMed ID = 26919432 ] [ RRC reference ]

Kim KW, Tang NH, Andrusiak MG, Wu Z, Chisholm AD, Jin Y.
A Neuronal piRNA Pathway Inhibits Axon Regeneration in C. elegans.
Neuron 2018 97(3) 511-519.e6 
[ PubMed ID = 29395906 ] [ RRC reference ]