Mutants (Isolated)


Allele Nametm395
Sequence NameK08E3.7
CGC Namepdr-1
Worm BaseAllele Name tm395
CGC Name pdr-1
Sequence K08E3.7
Phenotypehomozygous viable, Dr. C. Rongo: normal GLR-1::GFP expression. Dr. R. Baumeister: Hum. Mol. Genetics 14, 3407 (2005).
Mutation site31601/31602-32081/32082 (480 bp deletion)
Putative gene structurejoin(30814..30882, 30928..31073, 31164..31600, 32013..32217, 32271..32345, 32392..32533)
Map position23.73
Map position of balancer
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Cabello J, Sämann J, Gómez-Orte E, Erazo T, Coppa A, Pujol A, Büssing I, Schulze B, Lizcano JM, Ferrer I, Baumeister R, Dalfo E.
PDR-1/hParkin negatively regulates the phagocytosis of apoptotic cell corpses in Caenorhabditis elegans.
Cell Death Dis 2014 5 e1120 
[ PubMed ID = 24625979 ] [ RRC reference ]

Song MH, Liu Y, Anderson DE, Jahng WJ, O'Connell KF.
Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors.
Dev. Cell 2011 20(4) 563-71 
[ PubMed ID = 21497766 ] [ RRC reference ]

Kramer LB, Shim J, Previtera ML, Isack NR, Lee MC, Firestein BL, Rongo C.
UEV-1 is an ubiquitin-conjugating enzyme variant that regulates glutamate receptor trafficking in C. elegans neurons.
PLoS ONE 2010 5(12) e14291 
[ PubMed ID = 21179194 ] [ RRC reference ]

Schiavi A, Maglioni S, Palikaras K, Shaik A, Strappazzon F, Brinkmann V, Torgovnick A, Castelein N, De Henau S, Braeckman BP, Cecconi F, Tavernarakis N, Ventura N.
Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans.
Curr. Biol. 2015 25(14) 1810-22 
[ PubMed ID = 26144971 ] [ RRC reference ]

Knowlton WM, Hubert T, Wu Z, Chisholm AD, Jin Y.
A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans.
Front Neurosci 2017 11 263 
[ PubMed ID = 28539870 ] [ RRC reference ]

Nyamsuren O, Faggionato D, Loch W, Schulze E, Baumeister R.
A mutation in CHN-1/CHIP suppresses muscle degeneration in Caenorhabditis elegans.
Dev. Biol. 2007 312(1) 193-202 
[ PubMed ID = 17961535 ] [ RRC reference ]

Springer W, Hoppe T, Schmidt E, Baumeister R.
A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress.
Hum. Mol. Genet. 2005 14(22) 3407-23 
[ PubMed ID = 16204351 ] [ RRC reference ]