Mutants (Isolated)

tm3802

Allele Nametm3802
Allele TypeNormal
Sequence NameC38H2.1
Gene Nametbc-8
Worm BaseAllele Name tm3802
Gene Name tbc-8
Sequence C38H2.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 13064/13065-AAA-13442/13443 (378 bp deletion + 3 bp insertion)
ChromosomeIII
Putative gene structurejoin(7589..7713, 8272..8389, 8942..9267, 9433..9506, 11248..11375, 11850..11886, 12258..12611, 12817..12982, 13230..13283, 13332..13533, 13696..13863, 13953..14081, 14129..14271, 14318..14415, 14461..14570, 14794..14890, 15240..15410, 15455..15546)
Map position2.47
Balancer
Map position of balancer
Sequence of primersExtFwd:CCCTTTTTGTGCCTAGCAAC,IntFwd:ACTCCCCGAGCAGCTGATAT,ExtRev:GTAAGCAGGGTTACTGTATG,IntRev:TGGTTGCCTCTCTCACCTGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hannemann M, Sasidharan N, Hegermann J, Kutscher LM, Koenig S, Eimer S.
TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.
PLoS Genet 2012 8(5) e1002722 
[ PubMed ID = 22654674 ] [ RRC reference ]