Mutants (Isolated)

tm3659

Allele Nametm3659
Allele TypeNormal
Sequence NameY49E10.20
Gene NameY49E10.20
Worm BaseAllele Name tm3659
Gene Name Y49E10.20
Sequence Y49E10.20
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 86970/86971-87664/87665 (694 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(86322..86411, 86465..86660, 86709..86952, 87032..87413, 87518..87646, 87943..88192, 89068..89255, 89317..89442))
Map position17.88
Balancer
Map position of balancer
Sequence of primersIntFwd:TTCGTCGGATTGTCGCTGTA,ExtRev:AATGGTCTCCGAGGCTCCGT,ExtFwd:CCAGCACAAGACGTCCGTAC,IntRev:GGCTCCGTATATTACGGTAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Fang J, Wang J, Wang Y, Liu X, Chen B, Zou W.
Ribo-On and Ribo-Off tools using a self-cleaving ribozyme allow manipulation of endogenous gene expression in C. elegans.
Commun Biol 2023 6(1) 816 
[ PubMed ID = 37542105 ] [ RRC reference ]

Corrionero A, Horvitz HR.
A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis.
Curr Biol 2018 28(10) 1522-1535.e5 
[ PubMed ID = 29731301 ] [ RRC reference ]

Li Y, Chen B, Zou W, Wang X, Wu Y, Zhao D, Sun Y, Liu Y, Chen L, Miao L, Yang C, Wang X.
The lysosomal membrane protein SCAV-3 maintains lysosome integrity and adult longevity.
J Cell Biol 2016 215(2) 167-185 
[ PubMed ID = 27810910 ] [ RRC reference ]