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Mutants (Isolated)

Allele Name		tm327
Sequence Name		B0303.9
CGC Name		vps-33.1
Worm Base	Allele Name	tm327
	CGC Name	vps-33.1
	Sequence	B0303.9
Phenotype		maternal, embryonic lethal. Dr. G. Hermann: unable to find lethals. Dr. G. Ruvkun: no effect on dauer arrest. Dr. C. Yang: slightly Dpy, cell corpses degradation defects.
Mutation site		21444/21445-22118/22119 (674 bp deletion)
Chromosome		III
Putative gene structure		join(20715..20771, 20828..20950, 21008..21169, 21342..21439, 21533..22043, 22090..22252, 22299..22915)
Map position		-0.11
Balancer		dpy-13 or eT1 IV
Map position of balancer		0
Sequence of primers		ExtRev:CGGATGGATCGATATGCTCT,IntFwd:GACTCGGTGTTTGGGAAGAC,ExtFwd:ATGCTAGAAGGCGCACTGTT,IntRev:GAGTCGGACGACGATTGATT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Gengyo-Ando K, Kage-Nakadai E, Yoshina S, Otori M, Kagawa-Nagamura Y, Nakai J, Mitani S. Distinct roles of the two VPS33 proteins in the endolysosomal system in Caenorhabditis elegans. Traffic 2016 17(11) 1197-1213  [ PubMed ID = 27558849 ] [ RRC reference ] Liu K, Jian Y, Sun X, Yang C, Gao Z, Zhang Z, Liu X, Li Y, Xu J, Jing Y, Mitani S, He S, Yang C. Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion. J Cell Biol 2016 212(2) 181-98  [ PubMed ID = 26783301 ] [ RRC reference ] Xiao H, Chen D, Fang Z, Xu J, Sun X, Song S, Liu J, Yang C. Lysosome biogenesis mediated by vps-18 affects apoptotic cell degradation in Caenorhabditis elegans. Mol Biol Cell 2009 20(1) 21-32  [ PubMed ID = 18923146 ] [ RRC reference ]