Mutants (Isolated)

tm3146

Allele Nametm3146
Allele TypeBalanced
Sequence NameF25H8.3
Gene Namegon-1
Worm BaseAllele Name tm3146
Gene Name gon-1
Sequence F25H8.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [T13H10] 4793/4794-CACATGACCCAATTCAT-[T13H10] 5227/5228 (434 bp deletion + 17 bp insertion)
ChromosomeIV
Putative gene structurecomplement(join(28250..29281, 29330..29526, 29624..29760, 29809..29989, 30036..30387, 30434..30607, 31081..31254, 31314..31484, 179..460, 505..663, 715..1200, 1247..1507, 1565..2435, 2487..2928, 3026..3235, 3286..3614, 4003..4151, 4207..4317, 4368..4524, 4574..4668, 4714..5261, 6292..6441, 6486..6552, 6596..6770, 6821..7070, 7118..7180, 7244..7600, 7933..8053, 10883..10951, 14945..14992))
Map position4.45
BalancernT1,nT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:TCCGTCGGCCCATGGCATAT,IntFwd:AGCCCATCTGGCTTCCGTAG,ExtRev:GGGTGTTGTGTAATAGCCCA,IntRev:GTGGGTCCCCTATAGCTAAT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Cornwell A, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
bioRxiv 2023   
[ PubMed ID = 38045350 ] [ RRC reference ]

Yoshina S, Sakaki K, Yonezumi-Hayashi A, Gengyo-Ando K, Inoue H, Iino Y, Mitani S.
Identification of a novel ADAMTS9/GON-1 function for protein transport from the ER to the Golgi.
Mol Biol Cell 2012 23(9) 1728-41 
[ PubMed ID = 22419820 ] [ RRC reference ]

Yoshina S, Mitani S.
Loss of C. elegans GON-1, an ADAMTS9 Homolog, Decreases Secretion Resulting in Altered Lifespan and Dauer Formation.
PLoS One 2015 10(7) e0133966 
[ PubMed ID = 26218657 ] [ RRC reference ]