Mutants (Isolated)

tm306

Allele Nametm306
Sequence NameF15B9.7
CGC Namefmi-1
Worm BaseAllele Name tm306
CGC Name fmi-1
Sequence F15B9.7
Phenotypehomozygous viable. Dr. A. Colavita: no defects in VC axon guidance or morphology. Dr. G. Garriga: HSN axon normal. Dr. H. Sawa: no Psa phenotype. Dr. M. Herman: minor B cell polarity defect.
Mutation site[W07G4] 9426/9427-GA-[W07G4] 10248/10249 (822 bp deletion)
ChromosomeV
Putative gene structurejoin(31209..31714, 32029..32173, Z78018.1:230..295, Z78018.1:481..615, Z78018.1:2665..3356, Z78018.1:3401..3506, Z78018.1:3575..4138, Z78018.1:4220..4433, Z78018.1:4839..4924, Z78018.1:5216..5370, Z78018.1:5652..5911, Z78018.1:5958..6483, Z78018.1:6530..6652, Z78018.1:7190..7431, Z78018.1:7480..7605, Z78018.1:8210..8435, Z78018.1:8487..8580, Z78018.1:8630..8740, Z78018.1:8822..8922, Z78018.1:9218..10080, Z78018.1:10138..10541, Z78018.1:10589..11153, Z78018.1:11201..11592, Z78018.1:11645..11958, Z78018.1:12262..12514, Z78018.1:12563..13126)
Map position4.81
Balancer
Map position of balancer
Sequence of primersIntRev:AAAAGTTCCCCACCATCCAG,IntFwd:GTTGCGTTCGAGAACACGTA,ExtFwd:CCATGGTGACTGTGATACGC,ExtRev:TTCTTGCACTGACATGCTCC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Wu M, Herman MA.
A novel noncanonical Wnt pathway is involved in the regulation of the asymmetric B cell division in C. elegans.
Dev. Biol. 2006 293(2) 316-29 
[ PubMed ID = 16631156 ] [ RRC reference ]

Huarcaya Najarro E, Ackley BD.
C. elegans fmi-1/flamingo and Wnt pathway components interact genetically to control the anteroposterior neurite growth of the VD GABAergic neurons.
Dev. Biol. 2013 377(1) 224-35 
[ PubMed ID = 23376536 ] [ RRC reference ]

Najarro EH, Wong L, Zhen M, Carpio EP, Goncharov A, Garriga G, Lundquist EA, Jin Y, Ackley BD.
Caenorhabditis elegans flamingo cadherin fmi-1 regulates GABAergic neuronal development.
J. Neurosci. 2012 32(12) 4196-211 
[ PubMed ID = 22442082 ] [ RRC reference ]

Langenhan T, Prömel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, Kohara Y, Avery L, Vakonakis I, Schnabel R, Russ AP.
Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo.
Dev. Cell 2009 17(4) 494-504 
[ PubMed ID = 19853563 ] [ RRC reference ]

Sanchez-Alvarez L, Visanuvimol J, McEwan A, Su A, Imai JH, Colavita A.
VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans.
PLoS Genet. 2011 7(9) e1002257 
[ PubMed ID = 21912529 ] [ RRC reference ]