Mutants (Isolated)


Allele Nametm2912
Sequence NameF02E8.3
CGC Nameaps-2
Worm BaseAllele Name tm2912
CGC Name aps-2
Sequence F02E8.3
Phenotypelethal or sterile. Dr. O. Blacque: could not assess Dyf phenotype due to lethality.
Mutation site11246/11247-11440/11441 (194 bp deletion)
Putative gene structurejoin(10598..10684, 10736..10915, 11285..11446)
Map position-7.58
BalancerNot Yet Balanced
Map position of balancer
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Wang L, Audhya A.
In vivo imaging of C. elegans endocytosis.
Methods 2014 68(3) 518-28 
[ PubMed ID = 24704355 ] [ RRC reference ]

Hollopeter G, Lange JJ, Zhang Y, Vu TN, Gu M, Ailion M, Lambie EJ, Slaughter BD, Unruh JR, Florens L, Jorgensen EM.
The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex.
Elife 2014 3  
[ PubMed ID = 25303366 ] [ RRC reference ]

Garafalo SD, Luth ES, Moss BJ, Monteiro MI, Malkin E, Juo P.
The AP2 clathrin adaptor protein complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of Caenorhabditis elegans.
Mol Biol Cell 2015 26(10) 1887-900 
[ PubMed ID = 25788288 ] [ RRC reference ]

Kuwahara T, Koyama A, Koyama S, Yoshina S, Ren CH, Kato T, Mitani S, Iwatsubo T.
A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans.
Hum Mol Genet 2008 17(19) 2997-3009 
[ PubMed ID = 18617532 ] [ RRC reference ]