Mutants (Isolated)

tm2877

Allele Name

tm2877

Sequence Name

C43H6.9

CGC Name

glr-7

Worm Base

Allele Name

tm2877

CGC Name

glr-7

Sequence

C43H6.9

Phenotype

homozygous viable. Dr. K. Ashrafi: wild-type Nile Red staining. Dr. I. Mori: normal thermotaxix at 20C.

Mutation site

19770/19771-CTCTCTGATGCGCTTCCTT-20253/20254 (483 bp deletion + 19 bp insertion)

Chromosome

Putative gene structure

complement(join(19514..19745, 19798..19930, 19977..20167, 20215..20325, 20383..20521, 21268..21347, 21395..21843, 21892..21954))

Map position

-15.56

Balancer

Map position of balancer

Sequence of primers

IntRev:TTCCGGCCGTTTGGTTGCTG,ExtRev:GGGAGTAAGCTATAGCACTG,IntFwd:TCATCCGATGAGTCAGGGCA,ExtFwd:AACACAGCCTGAGCCCAGTC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Cunningham KA, Hua Z, Srinivasan S, Liu J, Lee BH, Edwards RH, Ashrafi K.
AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans.
Cell Metab. 2012 16(1) 113-21
[ PubMed ID = 22768843 ] [ RRC reference ]

Li Z, Li Y, Yi Y, Huang W, Yang S, Niu W, Zhang L, Xu Z, Qu A, Wu Z, Xu T.
Dissecting a central flip-flop circuit that integrates contradictory sensory cues in C. elegans feeding regulation.
Nat Commun 2012 3 776
[ PubMed ID = 22491324 ] [ RRC reference ]

Bhatla N, Droste R, Sando SR, Huang A, Horvitz HR.
Distinct Neural Circuits Control Rhythm Inhibition and Spitting by the Myogenic Pharynx of C. elegans.
Curr. Biol. 2015 25(16) 2075-89
[ PubMed ID = 26212880 ] [ RRC reference ]

Hardaway JA, Sturgeon SM, Snarrenberg CL, Li Z, Xu XZ, Bermingham DP, Odiase P, Spencer WC, Miller DM 3rd, Carvelli L, Hardie SL, Blakely RD.
Glial Expression of the Caenorhabditis elegans Gene swip-10 Supports Glutamate Dependent Control of Extrasynaptic Dopamine Signaling.
J. Neurosci. 2015 35(25) 9409-23
[ PubMed ID = 26109664 ] [ RRC reference ]