Mutants (Isolated)

tm2760

Allele Nametm2760
Allele TypeBalanced
Sequence NameY53G8AR.3
Gene Nameral-1
Worm BaseAllele Name tm2760
Gene Name ral-1
Sequence Y53G8AR.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 31342/31343-31661/31662 (319 bp deletion)
ChromosomeIII
Putative gene structurejoin(31144..31200, 31276..31341, 32350..32471, 32777..32863, 34473..34650, 35947..36078)
Map position-7.29
BalancerqC1 [e1259 q339 qIs26]
Map position of balancer
Sequence of primersIntFwd:TGCAGGTTATTATGGTCGGA,ExtRev:CCGAAACTCGTTTGTAGCCT,IntRev:CCCTCACCACTTCGATAGTA,ExtFwd:CGTACCCCTCAACTGTCGTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Shin H, Braendle C, Monahan KB, Kaplan REW, Zand TP, Mote FS, Peters EC, Reiner DJ.
Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.
PLoS Genet 2019 15(5) e1008056 
[ PubMed ID = 31086367 ] [ RRC reference ]

Reiner DJ, Lundquist EA.
Small GTPases.
WormBook 2018 2018 1-65 
[ PubMed ID = 27218782 ] [ RRC reference ]

Zand TP, Reiner DJ, Der CJ.
Ras effector switching promotes divergent cell fates in C. elegans vulval patterning.
Dev Cell 2011 20(1) 84-96 
[ PubMed ID = 21238927 ] [ RRC reference ]