Mutants (Isolated)

tm2391

Allele Nametm2391
Allele TypeBalanced
Sequence NameF46A9.5
Gene Nameskr-1
Worm BaseAllele Name tm2391
Gene Name skr-1
Sequence F46A9.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [F46A9]29584/29585-[F30A10]257/258 (435 bp deletion)
ChromosomeI
Putative gene structurejoin([F46A9] 29447..29527, 29712..29867, [F30A10] 106..225, 271..444)
Map position3.77
Balancerunc-3 (e151) X
Map position of balancer
Sequence of primersIntFwd:ATCCGAGGCGGCAAAGGAAC,ExtFwd:CGCATCATACGACACACTCA,IntRev:GGGTAATTTAATCCTCGCAC,ExtRev:AGGACAATGTGTGAAGTGTG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Wu CW, Deonarine A, Przybysz A, Strange K, Choe KP.
The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK.
PLoS Genet 2016 12(10) e1006361 
[ PubMed ID = 27776126 ] [ RRC reference ]

C. elegans Deletion Mutant Consortium.
large-scale screening for targeted knockouts in the Caenorhabditis elegans genome.
G3 (Bethesda) 2012 2(11) 1415-25 
[ PubMed ID = 23173093 ] [ RRC reference ]

Killian DJ, Harvey E, Johnson P, Otori M, Mitani S, Xue D.
SKR-1, a homolog of Skp1 and a member of the SCF(SEL-10) complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans.
Dev Biol 2008 322(2) 322-31 
[ PubMed ID = 18718460 ] [ RRC reference ]