Mutants (Isolated)

tm2282

Allele Nametm2282
Allele TypeNormal
Sequence NameF20D1.2
Gene Nametbc-1
Worm BaseAllele Name tm2282
Gene Name tbc-1
Sequence F20D1.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Y. Jin: no specific neuronal phenotype is found.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5563/5564-6079/6080 (516 bp deletion)
ChromosomeX
Putative gene structurejoin(5068..5123, 5174..5249, 5306..5515, 5581..5738, 6000..6123, 6169..6254, 6301..6532, 6735..6836, 6885..7080, 7132..7235, 7539..7772, 8447..8712, 8759..8840)
Map position21.61
Balancer
Map position of balancer
Sequence of primersExtFwd:GGCCGGAATAACGGACTCTC,IntFwd:CGGGACCAACCAATAATACA,ExtRev:CCGATACAATCGTGAAGCTC,IntRev:CTCTTATAGCCTCCCTGAAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Cornwell A, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
bioRxiv 2023   
[ PubMed ID = 38045350 ] [ RRC reference ]

Hannemann M, Sasidharan N, Hegermann J, Kutscher LM, Koenig S, Eimer S.
TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.
PLoS Genet 2012 8(5) e1002722 
[ PubMed ID = 22654674 ] [ RRC reference ]

Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA.
Identification of innate immunity genes and pathways using a comparative genomics approach.
Proc Natl Acad Sci U S A 2008 105(19) 7016-21 
[ PubMed ID = 18463287 ] [ RRC reference ]